Rate Limiting Steps Flashcards by Sadaf S

Q

Pyrimidine

A

aspartate transcarbamoylase

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Q

Purine

A

glutamine PRPP aminotransferase

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Q

Glycolysis

A

phosphofructokinase 1

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Q

Gluconeogenesis

A

pyruvate carboxylase

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Q

FA synthesis

A

acetyl coA carboxylase

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Q

FA oxidation

A

carnitine acyltransferase 1

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Q

TCA cycle

A

isocitrate dehydrogenase

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Q

Ketogenesis

A

HMGCoA synthase

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Q

Cholesterol Synthesis

A

HMGCoA reductase

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Q

Urea

A

carbamoyl phosphate synthase 1

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Q

Glycogen synthesis

A

glycogen synthase

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Q

Glycogenolysis

A

glycogen phosphorylase

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Q

Heme

A

ALA synthase

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Q

Aspartate transcarbamoylase inhibited by:

A

CTP

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Q

Hexokinase inhibited by:

A

Glucose-6-phosphate

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Q

Phosphofructokinase activated by:

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A

fructose 2,6 diphosphate, AMP, ADP

Q

Phosphofructokinase inhibited by:

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A

ATP, Citrate

Q

Pyruvate kinase activated by:

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A

ATP

Q

Protein kinase activated by:

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A

epinephrine

Q

Phosphorylase b kinase activated by:

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A

glucose-6-phosphate, AMP

Q

Phosphorylase b kinase & phosphorylase phosphatase inhibited by:

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A

Calcium

Q

Pyruvate carboxylase activated by:

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A

acetyl CoA

Q

Pyruvate carboxylase inhibited by:

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A

ADP

Q

AMP inihibits:

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A

fructose-1,6-biphosphatase

AMP activates:

pyruvate dehydrogenase

Pyruvate dehydrogenase inhibited by:

ATP, NADH, Acetyl CoA

ADP activates:

isocitrate dehydrogenase

Fructose-1,6-biphosphatase activated by:

AMP

Glycogen synthetase activated by:

glucose-6-phosphate