Rats/Mice Flashcards

1
Q

What is the suborder of rats and mice?

A

Myomorpha

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2
Q

How many toes are on the hindfoot of a rat or mice? How about the front foot?

A

5 hind, 4 front

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3
Q

(T/F) The external characteristisc of rats/mice is that they have short hair, long naked tails, erect rounded ears, protruding eyes, and pointed snouts.

A

True

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4
Q

(T/F) Rats and mice have one set of incisors which they are born with.

A

False, incisors grow continuously throught their life

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5
Q

What is the name of the gland that is used to generate heat during exposure to cold environment in rats/mice?

A

Hibernating gland or brown fat deposits

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6
Q

What is unique of the brain in rats/mice from the general mammals?

A

They lack gyri and sulci

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7
Q

What do the eyes of rats/mice secrete when they are stressed?

A

Porphyrin – iron containing reddish pigment

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8
Q

How many lung lobes are on the right and how many are on the left?

A

1 left, 3 right

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9
Q

(T/F) Rats have a large gallbladder while the mice lack a gallbladder.

A

False, rats lack a gallbladder and mouse do have gallbladders

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10
Q

(T/F) Rats are like horses because they cannot vomit.

A

True

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11
Q

In rats/mice, the resident microbes in the cecum will aid in the digestion of …

A

Cellulose and other plant materials

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12
Q

What will open in the genital papilla in females in rats/mice? What about the males?

A

Female – Urethra, Male - Penis

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13
Q

Why can the testicles be withdrawn into the abdomen in rats?

A

They have an open inguinal ring

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14
Q

Who has a shorter anogenital distance in rats/mice?

A

Female

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15
Q

How many pairs of nipples do rats have? How about mice?

A

Rats- 6, Mice - 5

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16
Q

(T/F) Males rats/mice are more aggressive than females and that is why you can house multiple females together.

A

True

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17
Q

How can you tell social dominance between rats/mice?

A

By barbering (excessive grooming/nibbling)

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18
Q

How should food be given to rats/mice?

A

Ad libitum

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19
Q

What are the two types of food you can give rats/mice, which one is the better one and why?

A

Pelleted and Powederd. Prefer pelleted so they can grind down their incisor teeth

20
Q

What are the 4 problems that come with an obese rat/mouse?

A

Cardiovascular, diabetes, joint problems, shortened lifespan

21
Q

When does estrus happen in rats/mice?

A

Occurs at night on day 3 of the estrous cycle

22
Q

Which is the prefered type of breeding in a research setting for rats/mice?

A

Harem mating

23
Q

How can you tell if mating has occurred in rats/mice?

A

Check for the presence of a sperm/vaginal plug

24
Q

What is the gestation time for rats and mouse?

A

Rats – 21 days avg, mouse 19 days avg

25
Q

What are the first signs of parturition in rast/mice?

A

Periodic stretching and extnesion of the hindlegs

26
Q

Why do we not want to handle the pups in mice?

A

Increases the interval to 20 min between pups, can cause delay of 4 hours for delivery of entire litter, increases the incidence of stillbirths

27
Q

When can we start measuring anogenital distance in rats/mice pups?

A

10-12 days

28
Q

What time to rats/mice pups do they open their eyes and when are they weaned?

A

Open eyes – 12-13 days, weaned 21-28 days

29
Q

Correctly connect the description to the term.

a) Lee Boot Effect
b) Whitten Effect
c) Bruce effect

  1. If female is exposed to a strange male before ova implants, the pregnancy will spontaneously terminate
  2. Absence of male in the room will lead to estrus suppression and increased psuodopregnancies
  3. Exposure to a strange male will result in induction of estrus
A

a-2
b-3
c-1

30
Q

What can result of handling rats/mice on the tip of the tail?

A

Degloving injury

31
Q

What is the ideal method to restraint a rat?

A

Thoracic encirclement

32
Q

(T/F) In an intraperitoneal injection on a rat/mouse, the needle has to go perpendicular to the body wall.

A

False the intestines could be penetrated

33
Q

Which medication should not be given IM since it can cause muscle necrosis and damage to the nerve in rats/mice?

A

Ketamine

34
Q

Where are the three veins that blood can be collected from in rats/mice?

A

Facial vein, saphenous vein, and lateral tail vein

35
Q

What location site would you poke if you wanted to get blood fromt he facial vein on a rat/mice?

A

Submandibular venipuncture

36
Q

What is the safe amout of blood to collect from a mouse?

A

<0.2mL

37
Q

What are the landmarks for gavage dosing in rats/mice?

A

Corner of the mouth to last rib on left side

38
Q

What are the paramenters to assess anesthetic depth on a rat/mouse?

A

Check reflexes, assess muscle tone, depth and rate of breathing, heart rate, blood pressure

39
Q

What type of bedding should you not use for rats/mice because it masks the ammonia from urine?

A

Cedar chip bedding

40
Q

What big main topics should you ask during a vet visit for rats/mice?

A

General signalment and a lot of questions about environment

41
Q

What are some clinical signs you can see with respiratory problems in rats/mice?

A

Head tilt - infection middle ear
Nasal discharge
Sneezing - do not do it normally
Coughing
Malocclusion

42
Q

What are some clinical signs you can see with eye problems in rats/mice?

A

Discharge
Conjunctivitis
Excess tears
Corneal opacity
Cataracts

43
Q

What kind of signs can you see if rats/mice are sick?

A

Dehydration
Emaciation
Hair loss
Trauma
Not grooming
Scratching
Masses
Joint swelling

44
Q

What are some viral causes for digestive problems in rats/mice?

A

Mouse parvovirus type 1
Mouse rotavirus
Reovirus type 3

45
Q

What are some viral causes for respiratory problems in rats/mice?

A

Pneumonia virus of mice (PVM)
Sendai virus*

46
Q

What does clostridium piliforme cause in rats/mice and what would you see in necropsy?

A

Tyzzer’s disease - see white spots in liver

47
Q

What is the most common mammary tumor in rats/mice?

A

Fibroadenoma