Rats/Mice

Question 1

What is the suborder of rats and mice?

Answer 1

Myomorpha

Question 2

How many toes are on the hindfoot of a rat or mice? How about the front foot?

Answer 2

5 hind, 4 front

Question 3

(T/F) The external characteristisc of rats/mice is that they have short hair, long naked tails, erect rounded ears, protruding eyes, and pointed snouts.

Answer 3

True

Question 4

(T/F) Rats and mice have one set of incisors which they are born with.

Answer 4

False, incisors grow continuously throught their life

Question 5

What is the name of the gland that is used to generate heat during exposure to cold environment in rats/mice?

Answer 5

Hibernating gland or brown fat deposits

Question 6

What is unique of the brain in rats/mice from the general mammals?

Answer 6

They lack gyri and sulci

Question 7

What do the eyes of rats/mice secrete when they are stressed?

Answer 7

Porphyrin – iron containing reddish pigment

Question 8

How many lung lobes are on the right and how many are on the left?

Answer 8

1 left, 3 right

Question 9

(T/F) Rats have a large gallbladder while the mice lack a gallbladder.

Answer 9

False, rats lack a gallbladder and mouse do have gallbladders

Question 10

(T/F) Rats are like horses because they cannot vomit.

Answer 10

True

Question 11

In rats/mice, the resident microbes in the cecum will aid in the digestion of …

Answer 11

Cellulose and other plant materials

Question 12

What will open in the genital papilla in females in rats/mice? What about the males?

Answer 12

Female – Urethra, Male - Penis

Question 13

Why can the testicles be withdrawn into the abdomen in rats?

Answer 13

They have an open inguinal ring

Question 14

Who has a shorter anogenital distance in rats/mice?

Answer 14

Female

Question 15

How many pairs of nipples do rats have? How about mice?

Answer 15

Rats- 6, Mice - 5

Question 16

(T/F) Males rats/mice are more aggressive than females and that is why you can house multiple females together.

Answer 16

True

Question 17

How can you tell social dominance between rats/mice?

Answer 17

By barbering (excessive grooming/nibbling)

Question 18

How should food be given to rats/mice?

Answer 18

Ad libitum

Question 19

What are the two types of food you can give rats/mice, which one is the better one and why?

Answer 19

Pelleted and Powederd. Prefer pelleted so they can grind down their incisor teeth

Question 20

What are the 4 problems that come with an obese rat/mouse?

Answer 20

Cardiovascular, diabetes, joint problems, shortened lifespan

Question 21

When does estrus happen in rats/mice?

Answer 21

Occurs at night on day 3 of the estrous cycle

Question 22

Which is the prefered type of breeding in a research setting for rats/mice?

Answer 22

Harem mating

Question 23

How can you tell if mating has occurred in rats/mice?

Answer 23

Check for the presence of a sperm/vaginal plug

Question 24

What is the gestation time for rats and mouse?

Answer 24

Rats – 21 days avg, mouse 19 days avg

Question 25

What are the first signs of parturition in rast/mice?

Answer 25

Periodic stretching and extnesion of the hindlegs

Question 26

Why do we not want to handle the pups in mice?

Answer 26

Increases the interval to 20 min between pups, can cause delay of 4 hours for delivery of entire litter, increases the incidence of stillbirths

Question 27

When can we start measuring anogenital distance in rats/mice pups?

Answer 27

10-12 days

Question 28

What time to rats/mice pups do they open their eyes and when are they weaned?

Answer 28

Open eyes – 12-13 days, weaned 21-28 days

Question 29

Correctly connect the description to the term. a) Lee Boot Effect b) Whitten Effect c) Bruce effect 1. If female is exposed to a strange male before ova implants, the pregnancy will spontaneously terminate 2. Absence of male in the room will lead to estrus suppression and increased psuodopregnancies 3. Exposure to a strange male will result in induction of estrus

Answer 29

a-2 b-3 c-1

Question 30

What can result of handling rats/mice on the tip of the tail?

Answer 30

Degloving injury

Question 31

What is the ideal method to restraint a rat?

Answer 31

Thoracic encirclement

Question 32

(T/F) In an intraperitoneal injection on a rat/mouse, the needle has to go perpendicular to the body wall.

Answer 32

False the intestines could be penetrated

Question 33

Which medication should not be given IM since it can cause muscle necrosis and damage to the nerve in rats/mice?

Answer 33

Ketamine

Question 34

Where are the three veins that blood can be collected from in rats/mice?

Answer 34

Facial vein, saphenous vein, and lateral tail vein

Question 35

What location site would you poke if you wanted to get blood fromt he facial vein on a rat/mice?

Answer 35

Submandibular venipuncture

Question 36

What is the safe amout of blood to collect from a mouse?

Answer 36

<0.2mL

Question 37

What are the landmarks for gavage dosing in rats/mice?

Answer 37

Corner of the mouth to last rib on left side

Question 38

What are the paramenters to assess anesthetic depth on a rat/mouse?

Answer 38

Check reflexes, assess muscle tone, depth and rate of breathing, heart rate, blood pressure

Question 39

What type of bedding should you not use for rats/mice because it masks the ammonia from urine?

Answer 39

Cedar chip bedding

Question 40

What big main topics should you ask during a vet visit for rats/mice?

Answer 40

General signalment and a lot of questions about environment

Question 41

What are some clinical signs you can see with respiratory problems in rats/mice?

Answer 41

Head tilt - infection middle ear Nasal discharge Sneezing - do not do it normally Coughing Malocclusion

Question 42

What are some clinical signs you can see with eye problems in rats/mice?

Answer 42

Discharge Conjunctivitis Excess tears Corneal opacity Cataracts

Question 43

What kind of signs can you see if rats/mice are sick?

Answer 43

Dehydration Emaciation Hair loss Trauma Not grooming Scratching Masses Joint swelling

Question 44

What are some viral causes for digestive problems in rats/mice?

Answer 44

Mouse parvovirus type 1 Mouse rotavirus Reovirus type 3

Question 45

What are some viral causes for respiratory problems in rats/mice?

Answer 45

Pneumonia virus of mice (PVM) Sendai virus*

Question 46

What does clostridium piliforme cause in rats/mice and what would you see in necropsy?

Answer 46

Tyzzer's disease - see white spots in liver

Question 47

What is the most common mammary tumor in rats/mice?

Answer 47

Fibroadenoma