Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Hematology > RBC ANOMALIES & PATHWAYS > Flashcards

RBC ANOMALIES & PATHWAYS Flashcards

(91 cards)

Start Studying
1
Q

conditions with high rbc count

A 
polycythemia vera
cardiovascular heart disease
lung disease
dehydration
acute poisoning
high altitude
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

erythrocyte count, hg and hematocrit are SLIGHTLY lower in 3 significant situations

A

after age of 50
in recumbency
after meals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

non oxidative that handles 90% utilization of glucose in rbcs

A

embden meyerhof pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

converts methemoglobin to hgb

A

methemoglobin reductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

normal values for female

A

4.5-5.5 million/ cu mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

rbcs with single elongated point/tail

A

teardrop cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

necessary for the production of 2,3-diphosphoglycerate

A

luebering rapoport pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

rbc count for newborn

A

5.7 million/ cu mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

also known as phosphogluconate pathway

A

hexose monophosphate shunt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

end result for EM pathway

A

2 atps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

normal values of rbcs for male (conventional and SI)

A

5.5-6.5 million/cu. mm; x10 12/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

HM shunt depends on what enzyme

A

glucose-6-phosphate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

converts NADP to NADPH

A

glucose-6-phosphate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

inclusion produced when there is a defect in the pathway (g6pd deficiency)

A

heinz bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

variation in shape

A

poikilocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

conditions with lower rbc count

A

anemia
hemorrhage
oligocythemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

enzyme needed for the production of 2,3-DPG

A

phosphofructokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

present in dehydration and azotemia

A

echinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

low 2,3-dpg

high oxgyen affinity

A

deoxyhemoglobin/ tensed form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

pathway which maintains the iron in hb in its reduced state

A

methemoglobin reductase pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

can be seen in pk deficiency, uremia, cancer of the stomach, acute blood loss

A

burr cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

rbs with regularly spiculated surface rounded at the tip

A

echinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

intrinisic abnormality of red cell

A

schistocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

projections of the spicule is more rounded than echinocytes

A

burr cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
in 3D, they are cup-shaped
stomatocytes
30
other name for dacrocytes
teardrop cells
31
have 2 small areas of central pallor separated by a band of hb
knizocyte
32
abnormality which is associated with myelofibrosis and myeloid metaplasia
teardrop cells
33
other name for ovalocytes
elliptocytes
34
results from red cell fragmentation which may be caused by mechanical damge, exposure to heat and toxix substances
microspherocytes
35
seen in MAHA
schistocyte
36
due to polimerization of Abnormal hb-hbs
sickle cells
37
only inclusion bodies which is visible in wet prep
howell jolly bodies
38
elongated rbc with slit-like central pallor
stomatocytes
39
variation in cell size
anisocytosis
40
ellipse, cigar-shaped rbc
elliptocytes
41
can be seen in abetalipoproteinemia, alcoholic cirrhosis, splenectomy, mcleod syndrome
acanthocyte
42
destruction in which rbc lyses in blood vessels due to traumatic causes
intravascular hemolysis
47
low oygen affinity | high 2,3-dpg
oxyhemoglobin/ relaxed form
48
other name for codocytes
target cell
50
feature of megaloblastic anemia
macro ovalocyte
51
resemble a pinched bottle
knizocyte
52
not visible in supravital stains
cabot rings
53
4 peripheral membrane proteins
spectrin ankyrin band 4.1 actin
54
3 problems for patients with sickle cell disease
vasooclusive,hematological and infection crises
55
band 3 contains ____ which gives the (-) charge taht causes distance bet rbcs
sialic acid
56
rings that are probably microtubules remaining from mitotic spindle
cabot rings
57
abnormality in the membrane proteins
spherocytes
59
cells seen in acute, severely hemolytic anemia, g6pd deficiency and hereditary lipoprotein deficiency
pyknocytes
60
may be seen in lead poisoning or with impaired hb synthesisin megaloblastic anemia
coarse stippling
61
stain used for proteins
coomasie blue
62
% for proteins
52%
63
smooth round remnants of dna
howell jolly bodies
64
proteins are extracted by powerful detergents
sodium dodecyl sulphate
65
proteins which is loosely connected with the membrane
peripheral protein
66
what are the supravital stains
new methylen blue | brilliant cresyl blue
67
resemble a stack of coins
rouleaux formation
68
commonly seen when there is increased polychromatophilia
fine stippling
69
% of Lipids
40%
70
positive using feulcen stain
howell jolly bodies
71
2 inclusion bodies which is composed of rna
basophilic stippling | reticulum of reticulocyte
72
angular blue dots and represent ferric ions
howell jolly bodies
73
not visible in wright stain
siderotic granules
74
seen in severe liver disease, alcoholism, rh null disease
stomatocyte
75
horn shaped cell
keratocyte
76
rbc with high MCHC
spherocytes
78
rbc which results from squeezing and fragmentation during splenic passage
teardrop cells
79
2 inclusion bodies which is + in prussian blue
pappenhempimer bodies | siderotic granules
82
protein which penetrates the phospholipd bilayer
integral protein
83
principal integral protein
band 3
84
HE which includes hereditary pyropoikilocytosis with elliptocytes that may be rod shaped
common HE
85
enzyme which controls the esterification of plasma cholesterol
LCAT
86
what does LCAT mean
lecithin cholesterol acyl transferase
87
diagnostic implications for target cells
chronic liver disease thalassemia hemoglobinopathies
88
size of normocyte
7-8 um
89
destruction due to rupture of cell membrane
extravascular destruction
90
other name for crenated cell
echinocytes
91
% of CHO
8%
92
clumping of red cells
agglutination
93
causd by excess of red cell membrane relative to the hgb content of the cell
target cell
94
female have lower lower RBC count than men due to what hormone
estrogen
95
enzyme which maintains the EM pathway
pyruvate kinase
96
seen in hemoglobinopathies
target cell
97
spicules resembling 2 horns, result from a ruptured vacuole
keratocyte
99
other name for drepanocyte
sickle cell
106
mature red blood cells
erythrocytes
111
anaerobic metabolism of glucose
embden meyerhof pathway
125
seen in congenital dyserythropoietic anemia
macro ovalocytes
131
RBCs with irregularly spiculated surface
acanthocyte
143
regularly spiculated surface
burr cells
178
other name for erythrocytes
discocytes

Hematology (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions