RBC Structure & Metabolism Flashcards

1
Q

The word for too few red cells

A

Anemia

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2
Q

The word for too many red cells

A

Polycythemia

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3
Q

What is the production of red cells?

A

Erythropoiesis

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4
Q

Soft bony tissue between bony trabecular

A

Bone marrow

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5
Q

Hematopoietic tissue

A

Red marrow

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6
Q

Fat cells in bone marrow

A

Yellow marrow

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7
Q

Place where hematopoietic tissue meets the vascular area and cells are released into circulation.

A

Sinus area

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8
Q

The sinus area is lined with what kind of cell?

A

Reticuloendothelial cells (histiocytes/macrophages) of the RES (reticuloendothelial system)

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9
Q

Bone marrow cell that is specific to red cell lineage

A

Erythroblastosis

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10
Q

Bone marrow cell specific to white cell lineage.

A

Myeloblast

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11
Q

Platelet precursor cell

A

Megakaryocyte

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12
Q

Normal cells of bone marrow

A

Lymphocyte

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13
Q

6 maturation generalizations

A
  1. Size decreases
  2. N:C ratio decreases
  3. Condensation of DNA
  4. Nucleoli number decreases
  5. Microorganelles decreases
  6. Cytoplasmic components increase
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14
Q

5 RBC Maturation Nomenclature

A
  1. Pronormoblast
  2. Basophilic normoblast
  3. Polychromatophilic normoblast
  4. Orthochromic normoblast
  5. Diffusely basophilic erythrocytes
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15
Q

What is the RBC membrane functions?

A

Separates intracellular contents from the extracellular environment.

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16
Q

Why is it important for the RBC membrane to be flexible?

A

So that it can change shape to pass through capillaries and filtering spleen

17
Q

RBC membrane is made up of what protein complex?

A

Biphospholipid protein complex

18
Q

Integral proteins are responsible for linking what to the external environment?

A

Internal cytoplasm

19
Q

This type of protein supports the membrane.

A

Skeletal proteins

20
Q

The integral protein Glycoprotein A consists of what blood group antigens?

A
  1. ABO
  2. M
  3. N
21
Q

This integral protein contains sialic acid, giving red cells their negative charge.

A

Glycophorin A