Recurrent Miscarriage GTG 2023 Flashcards
(20 cards)
Recurrent miscarriage def
3 or more first trimester
Most common cause of Recurrent miscarriage
Anti phospholipid syndrome
Recurrent Miscarriage intake in AFS when Asprin and Heparin
From + ve test until 34 weeks
Recurrent Miscarriage Progesterone prescription
400mg Micronised vaginal progesterone twice daily at time of bleeding until 16 weeks
Recurrent Miscarriage risk factors
Maternal age
No of previous miscarriages
Advance paternal age >= 40 yr
Advance Maternal age >= 35 y yr
Least risk of miscarriage age group
20 to 24 year = 11%
35 -39 years risk of miscarriage
25%
40 -44 years risk of miscarriage
51%
> = 45 years risk of miscarriage
93%
Increase risk of miscarriage factors
Advance Maternal age
Advance paternal age
Smoking
Alcohol
Caffeine
Black ethnic
Increase risk of Recurrent Miscarriage factor
No of previous miscarriages
Bmi <19 or >25 kg/m2
When to give inherited Thrombophilia Heparin
2nd trimester
% of pregnancy loss after 3 consecutive Miscarriage
40%
Apla % in Recurrent Miscarriage
15%
Arcuate uterus more miscarriage in
2nd trimester
Septate uterus more miscarriage in
1st trimester
Alpa and Recurrent Miscarriage no pharmaceutical intervention % of successful pregnancy
10%
Prevalence of Apla in women with low risk obs hx
<2%
Investigation after 3rd Recurrent Miscarriage
- POCS
- APLA
- USG then Hysteroscopy
Investigation after 4th Recurrent Miscarriage
- APLA
- USG
- POCs > paternal Karyotype