References

Question 1

Beta arrestins

Answer 1

Rajagopal

Question 2

Biased ligands

Answer 2

Dewire

Question 3

Any pharmacology

Answer 3

Rand and Dale Pharmacology 7th edition

Question 4

CV drugs or actions

Answer 4

Klabunde CV Pharmacology

Question 5

Beta 1 Arg389Gly

Answer 5

Maqbool

Question 6

Arg389 diastolic blood

Answer 6

Johnson

Question 7

Remodelling Arg form

Answer 7

Terra

Question 8

del322-325 and Arg 389 - ten fold increase in developing heart failure

Answer 8

Small

Question 9

nAChR structure - M2 helices

Answer 9

Miyazawa

Question 10

Pilocarpine and epilepsy

Answer 10

Scorza

Question 11

Diseases

Answer 11

NHS

Question 12

Dopamine hypothesis

Answer 12

Handbook of behavioural neuroscience

Question 13

Negative feedback on mesolimbic by mesocortical

Answer 13

Pariyadath

Question 14

Schizo and amphetamines

Answer 14

Breier

Question 15

MPP+ - damage by mitochondrial release of ROS and cell apoptosis

Answer 15

Kalivendi

Question 16

Optimisation of L-DOPA

Answer 16

Brooks

Question 17

Serotonin and Noradrenaline

Answer 17

Moret

Question 18

Any drugs on list

Answer 18

Mayo

Question 19

GABAa and other ligand gated ion channel structures

Answer 19

Miller

Question 20

GABAa

Answer 20

Jacob

Question 21

Extrasynaptic GABAa vs synaptic GABAa (tonic vs phasic inhibition)

Answer 21

Belelli

Question 22

GABAb

Answer 22

Frangag

Question 23

Six hallmarks, emerging hallmarks, enabling characteristics, microenvironment

Answer 23

Hannahan and Weinberg

Question 24

Approved RTK drugs

Answer 24

Imai

Question 25

Cancer hallmarks actual details

Answer 25

Molecular biology of cell

Question 26

Hypoxic cell resistance

Answer 26

Rockwell

Question 27

Taxanes and p glycoprotein

Answer 27

Hendrikx

Question 28

Phamacogenetics and cancer

Answer 28

Patel

Question 29

Trastuzumab

Answer 29

Vu

Question 30

CTLA-4

Answer 30

Laurent

Question 31

CYP3a4 inactivates Irinotecan

Answer 31

Sai

Question 32

Oncolytic viruses

Answer 32

Kaufman

Question 33

AML syngeneic vs allogeneic

Answer 33

Gale

Question 34

Alkylating agents crosslinking

Answer 34

Deans

Question 35

Nitrogen mustards e.g. Clorambucil and Oxazophosphorines e.g. Cylcophosphamide

Answer 35

Emadi

Question 36

MGMT/AGT

Answer 36

Gerson

Question 37

Platinums

Answer 37

Wang

Question 38

Topo 2 Inhibitors

Answer 38

Hande

Question 39

PARP inhibitors

Answer 39

Sonnenblick

Question 40

PGE2

Answer 40

Gheun Ho

Question 41

Angiotensin receptors

Answer 41

Fhyrquist

Question 42

MAS receptor

Answer 42

Santos

Question 43

RAAS polymorphisms

Answer 43

Danser

Question 44

PARADIGM study ARNI superior to just ACEi

Answer 44

Mcmurray

Question 45

Calcium channel structure

Answer 45

Catterall

Question 46

T type calcium channels

Answer 46

Chiang

Question 47

CYP2D6 numbers

Answer 47

Bradford