Reflexes Flashcards
(40 cards)
Describe neural regulation of circulation, including various reflexes that influence it.
Nervous regulation of circulation involves
① redistributing blood to different areas of the body.
② increasing the heart’s pumping activity
③ providing rapid BP control
Only the SNS provides ANS circulatory control through the vasomotor center in the medulla (and pons)Which has vasoconstrictor fibers throughout circulation .These fibers secrete NE onto alpha fibers, causing vasoconstriction. The vasodilator area inhibits this mechanism and sensory area regulates both.
Nervous Regulation of Circulation
Local flow control locally
Nervous control for
Redistributing blood flow to different body areas
Increasing heart’s pumping activity
Providing rapid BP control
Regulated by autonomic nervous system (ANS)
Sympathetic
Circulation
Heart function
Parasympathetic
Heart Function
NOT circulation
Sympathetic Innervation
of Blood Vessels
Most tissues: all vessels except capillaries
Some tissues: precapillary sphincters & metarterioles
Innervation of small arteries/arterioles can increase resistance and decrease flow
Innervation of large vessels (veins) can decrease volume/affect heart pumping
Control by the CNS
Vasoconstrictor fibers (throughout circulation)
Especially kidneys, intestines, spleen
Not as much brain, skeletal muscle
Vasomotor Center
Medulla/lower pons
Parasympathetic impulses to heart (through vagus)
Sympathetic through spinal cord/PNS to all arteries, arterioles and veins
Vasoconstrictor area
SNS vasoconstrictor neurons throughout spinal cord
Vasodilator area
Inhibit vasoconstrictor area
Sensory area
Receives signals from vagus & glossopharyngeal nerves
Regultes vasoconstrictor & vasodilator areas
Vasomotor Tone
Continuous signals from vasoconstrictor area – sympathetic tone
Sympathetic (lateral)
Increases heart rate & contractility
Generally increase when vasoconstriction occurs
Generally decrease when vasoconstriction inhibited
Parasympathetic (medial)
Decreases heart rate (vagus nerve)
Higher nervous centers can influence vasomotor center
Pons
Midbrain
Diencephalon
Hypothalamus – powerful regulator
Cerebral cortex
Vasoconstrictor neurotransmitter
NE
Adrenal Medulla Innervation
Causes medulla to release Epi and NE
Generally cause vasoconstriction
In tissues with β2 receptors, cause vasodilation
MAP can be increased by
Constricting most arterioles
Increase TPR and therefore CO
Constricting large vessels
Increase venous return and therefore CO
Increasing HR and contractility
Increase CO
These can occur within seconds
Exercise/fright
Constricting most arterioles
Increase TPR and therefore CO
Constricting large vessels
Increase venous return and therefore CO
Increasing HR and contractility
Increase CO
These can occur within seconds
Exercise/fright
Cardiovascular Reflexes & Responses
Vasovagal syncope
Baroreceptor reflex
Ischemic response
Atrial & pulmonary artery reflexes
Bainbridge reflex
Baroreceptor Reflex
Important in short term BP regulation
Increase in BP stretches baroreceptors
Increases the number of impulses from carotid sinus increases which results in
Inhibition of the vasoconstrictor
Activation of the vagal center
Causes AP through afferent neurons
Hering’s and glossopharyngeal or vagus
Integrating center is vasomotor center in medulla
Baroreceptors respond to changes in arterial pressure
Carotid sinus baroreceptors respond to pressures between 60 and 180 mmHg
Baroreceptors reflex is most sensitive at a pressure of ~100mmHg
Maintains relatively constant pressure despite changes in body posture
Moving from a supine to a standing position results in
an increase in heart rate
an increase in total peripheral resistance
constriction of veins
Baroreceptor Reflex Functions
Oppose changes (increase or decrease) in BP, reducing daily fluctuations
Adapt, so not helpful in long-term regulation of BP
Chemoreceptors
Remember chemoreceptors located in carotid bodies and aorta?
Their activation also activates vasomotor center in medulla to increase sympathetic stimulation