Reg 2 Flashcards
(202 cards)
Local anesthetics
Drugs used to produce reversible conduction blockade of impulses along central and peripheral nerve pathways
Regional anesthesia
insensibility of a part induced by interrupting the sensory nerve conductivity of that region of the body
The result of a conduction blockade of specific peripheral nerves or nerve groups
Esters:
Are less stable (shorter shelf life)
Metabolized in the plasma by pseudocholinesterases
More prone to cause allergic reactions
Amides
More stable
Metabolized by liver
Rare allergies
SPINAL
Small volume
Direct-Sheath
Rapid onset
Total neural block-both sensory and motor
Epidural/PNB
Large volume
Outside-Sheath
Slow onset
Block varies with dose
PERIPHERAL vs. CENTRAL
advantages
Segmental block Slow onset = time to Rx side effects Flexibility in density Flexibility in duration Less side effects
PERIPHERAL vs. CENTRAL
disadvantages
More technical & more failure
More time consuming
Greater LA volume- [>toxicity risk]
Faulty block
Definition spinal
It is the reversible chemical blockade of neuronal transmission produced by injection of a LA into the CSF contained in the subarachnoid space
goal of spinal
Render patient insensitive to surgical stimuli while producing minimal physiologic alteration
Types neuraxial anesthesia
Spinal
Epidural
Caudal: similar to epidural. But in sacrum. Kids only
neuraxial uses
Alternative to general anesthesia
Can be used in conjunction with GA
Post-operative analgesia: may use lower opioid use with and decreases incidence of atelectasis, hypoventilation, and aspiration pneumonia
Management of acute or chronic pain
advantages and system improvements with neuraxial
- Sympathectomy-mediated increases in tissue blood flow
- Improved oxygenation from decreased splinting
- Enhanced peristalsis
- Suppression of the neuroendocrine stress response
advantages spinal anesthesia
- Simple
- Predictable
- Fully conscious patient
- Analgesia into the post-op period
- Ideal for lower abdomen, pelvis/ perineum, and lower extremities
- Reduces risk of DVT
- Use small dose of LA, less toxicity
Disadvantages spinal anesthesia
-Sympathetic blockade 100% of the time =Hypotension -Intense motor blockade =May last for hours post-op -Surgeons complain “It takes too long
Absolute Contraindications
-Patient refusal
-Severe psychiatric disease:
May not cooperate
-Infection at the site
-Septicemia or bacteremia
Absolute Contraindications: cardiovascular
Cardiovascular disease:
-Severe aortic/mitral stenosis and septal hypertrophy
Absolute Contraindications: Fluid status
Severe hypovolemia:
- Can be corrected before the spinal
- Pt in shock
Absolute Contraindications CNS
CNS disease:
- MS or nerve injury
- Herpetic infections
- Increased ICP- brain herniation
Absolute Contraindications: allergies
Allergy to LA:
- Ester LA
- Reaction to the preservatives
Absolute Contraindications: blood
Blood clotting anomalies:
-Anticoagulant therapy
ASRA guidelines
relative Contraindications
-HIV: Associated with neurological manifestations -Surgery of unknown duration -Untreated chronic HTN: *Unstable BP after spinal *Greater drop in BP than normal pt -Procedures above the abdomen -Obesity
relative Contraindications
- Deformities of the spinal column
- Chronic HA or backache
- Bloody tap
- Multiple attempts
relative contraindication : blood clotting
- Minor abnormalities in blood clotting:
- ASA therapy
- Small dose of heparin
- Check coags before spinal insertion and document
- Risk for spinal hematoma
- Platelet count