Regional Anesthesia Flashcards
(168 cards)
The spinal cord extends from the foramen magnum to ___ in the adult and ranges from ____ cm, and to ___ in the newborn.
L1
42-45 cm
L3
The spinal cord terminates at conus medullaris and the ________ extends down and anchors in the lower sacral region.
Filum terminale
How many vertebrae?
How many pairs of spinal nerves?
33 vertebrae (7 cervical, 12 thoracic, 5 lumbar, 5 sacral, 4 coccygeal) 31 pairs of spinal nerves
What is the nerve group in the lower dural sac (L1 to S5)?
Cauda equina
List the structures traversed to arrive at the subarachnoid space.
- Skin
- Subcutaneous
- Supraspinous ligament (C7 to sacrum)
- Interspinous ligament
- Ligamentum flavum
- Epidural space
- Dura
- Arachnoid
- Subarachnoid space
Which ligament binds the epidural space posteriorly? Anteriorly?
Ligamentum flavum
Dura
Where is the ligamentum flavum the widest? Narrowest?
Wides at L2
Narrowest at C5
List the 3 spinal meninges.
- Dura mater
- Arachnoid
- Pia mater
Where is CSF found?
Subarachnoid space
Between the arachnoid and pia mater
What is the principle site of action for neuraxial blockade?
Nerve root
LA act on nerve rootlets, nerve roots, and the spinal cord
Factors with proven effects on distribution of drug include:
- Site of injection
- Anatomical shape of spinal column
- Patient height
- Angulation of needle
- Volume of CSF
- Characteristics of LA (baracity)
- Dose of LA
- Volume of LA
- Position of patient during injection
- Position of patient after injection
Uptake of LA occurs by ____ down a concentration gradient.
Diffusion
Uptake is greatest where the concentration of LA is the greatest
Elimination occurs by ______ via subarachnoid and epidural _______.
Vascular absorption
Blood vessels
The predominant action of sympathetic blockade due to LAs is ________.
Venodilation
Reduces VR, SV, CO, BP
What happens if sympathetic outflow from T1 to T4 is blocked by LAs?
Unopposed vagal stimulation
Bradycardia
Bradycardia following spinal injection is a result of what 2 things?
- Blockade of cardioaccelerator fibers (T1-T4)
2. Bainbridge reflex (decreased VR)
The best means for treating hypotension during spinal anesthesia is ________, not pharmacologic.
Physiologic
- Give IV fluids if not normovolemic (5 mL/kg)
- If normovolemic, give ephedrine or neo
When giving a fluid bolus for hypotension following a spinal injection, why avoid glucose containing solutions?
Glucose can act as a diuretic - worsen the situation
Explain why the patient may feel dyspneic under subarachnoid or epidural block.
As the sensory block reaches the level of T2-T4 - loss of perception of intercostal and abdominal wall movement
Apnea, if it occurs, under subarachnoid or epidural block is due to what?
Hypoperfusion of the respiratory centers in the medulla
Secondary to severe hypotension
Spinal or epidural: ability to control the spread of the anesthetic by controlling the specific gravity of the solution and the position of the patient.
Spinal
With cut-bevel needles (Quinke)…the bevel should face what in the sitting position? Lateral position?
Sitting position - face either R or L
Lateral position - face up or down
(to minimize trauma to the dura)
Anticoagulants and Neuraxial Anesthesia NSAIDS? Aspirin? Herbals? SubQ or minidose Heparin? IV Heparin? Chronic Warfarin? Ticlodipine? Clopidogrel? Abciximab? Eptifibatide and tirofiban? GPIIb/IIIa antagonists?
NSAIDS, Aspirin - OK Herbals - OK if alone SubQ or minidose Heparin - OK IV Heparin - NO, unless a normal PTT Chronic Warfarin - 4 days Ticlodipine - 14 days Clopidogrel - 7 days Abciximab - 24-48 hours Eptifibatide and tirofiban - 4-8 hours GPIIb/IIIa antagonists - 4 weeks
When a central nerve block is used and intra-op anticoagulation is initiated, it is recommended that heparin dosing be held for a least ___ hour after placement of the neuraxial anesthetic.
1 hour