Regulating the Cell Cycle Flashcards

Controlling the cell cycle, apoptosis, and cancer

1
Q

True or False: The controls on cell growth and division can be turned on and off

A

True

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2
Q

True or False: The rate of cell division slows when the healing process nears completion

A

True

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3
Q

What are cyclins?

A

A family of proteins that regulate the timing of the cell cycle in eukaryotic cells

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4
Q

What are internal regulators?

A

Internal regulators are proteins that respond to events inside a cell

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5
Q

What do internal regulators do?

A

They allow the cell to proceed only once certain processes have happened inside the cell

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6
Q

What are external regulators?

A

External regulators are proteins that respond to events outside the cell

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7
Q

What do external regulators do?

A

External regulators direct cells to speed up or slow down the cell cycle

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8
Q

What are growth factors?

A

Growth factors are external regulators that stimulate the growth and division of cells.

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9
Q

When are growth factors useful?

A

Growth factors are useful during embryonic development and wound healing

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10
Q

What is apoptosis?

A

Apoptosis is a process of programmed cell death

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11
Q

When is apoptosis important?

A

Apoptosis is important in the development of organisms by shaping the structure of tissues and organs

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12
Q

What is cancer?

A

Cancer is a disorder in which body cells lose the ability to control cell growth

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13
Q

How is a tumor formed?

A

A tumor is formed when cancer cells divide uncontrollably to form a mass of cells

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14
Q

What is a benign tumor?

A

A benign tumor is noncancerous

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15
Q

What does a benign tumor do?

A

It does NOT spread to surrounding healthy tissue

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16
Q

What is a malignant tumor?

A

A cancerous tumor

17
Q

What does a malignant tumor do?

A

It invades and destroys surrounding healthy tissue and can spread to other parts of the body

18
Q

What is the spread of cancer cells called?

A

Metastasis

19
Q

What do cancer cells do?

A

Cancer cells absorb nutrients needed by other cells, block nerve connections, and prevent organs from functioning

20
Q

How are cancers caused?

A

Defects in genes that regulate cell growth and division

21
Q

What are some of the sources of gene defects?

A

Smoking tobacco, radiation exposure, defective genes, and viral infection

22
Q

What is the most common damaged or defective gene in cancer cells?

A

The p53 gene

23
Q

What happens when there is a damage or defection in the p53 gene?

A

It causes cells to lose the information needed to respond to growth signals

24
Q

True or False: Some localized tumors can be removed by surgery

A

True

25
Q

True or False: many tumors cannot be treated with targeted radiation

A

False: many CAN be treated with targeted radiation

26
Q

What is chemotherapy?

A

The use of compounds that kill or slow the growth of cancer cells