Regulation of Gene Expression

Question 1

Two Types of Gene Regulation

Answer 1

Positive and Negative Regulation

Question 2

This regulation of when Expression is Quantitatively Increased

Answer 2

Positive Regulation

Question 3

It is an Element or Molecule that mediates negative regulation

Answer 3

• Negative Regulator
• Silencer
• Repressor

Question 4

2 types of Positive Regulator

Answer 4

• Mediation of Positive Regulator
• Inhibition of Negative Regulator

Question 5

Type of Gene whose expression Increases in response to an inducer or activator, have relatively low basal rates of transcription

Answer 5

Inducible Gene

Question 6

It results from a Constitutive mutation of a regulated or inducible gene and is expressed constitutively at a reasonably constant rate

Answer 6

Housekeeping Gene

Question 7

If the Regulator is Present the** Negative Regulation is** ______ and Positive Regulation is __________

Answer 7

Decreased, Increased

Question 8

If the Regulator is Absent the** Negative Regulation is** ______ and Positive Regulation is __________

Answer 8

Increased, Decreased

Question 9

• Is Characterized by an Increased extent of gene expression dependent on the inducing signal
• Commonly observed in Prokaryotes in response to sudden changes of intracellular concentration

Answer 9

Type A Response Pattern

Question 10

• Temporary increase in the amount of gene expression even in the continued presence of the regulatory signal
• Occurs during development of an organism

Answer 10

Type B Response Pattern

Question 11

It is the decreasing response to a repeated or continuous stimulus

Answer 11

Desensitization

Question 11

• Refers to the process by which a biological system return to its normal sensitivity after being desensitized

Answer 11

Response desensitization recovery

Question 12

• Is an** Increased extent of gene expression **that persists even after the termination signal
• Occurs during the development of differentiated function of a tissue or organ
• Irreversibel and Inherited alteration

Answer 12

Type C Response Pattern

Question 13

It is the smallest unit of genetic expression

Answer 13

Cistron

Question 14

• A linear array of genes involved in a metabolic pahtway
• Can be regulated by a single promoter or regulatory region

Answer 14

Operon

Question 15

Beta-Galactosidase

Answer 15

LacZ

Question 16

Lactose Permease

Answer 16

LacY

Question 18

Thiogalactoside transacetylase

Answer 18

LacA

Question 19

Lacl Repressor

Answer 19

Lacl

Question 20

Binding Site for the CAMP-binding protein

Answer 20

CRE