Regulation Of Transcription And Translation Flashcards
(3 cards)
1
Q
What stops translation
A
siRNA
miRNA
both break mRNA before it can be transcribed
2
Q
What changes transcription
A
-hypermethylation of DNA
-hypomethylation of histones
-mutation of DNA (changes base sequence) at promoter region
3
Q
What is siRNA
A
small interfering RNA
used for short term switching off of gene
The siRNA binds to a complementary sequence of mRNA. As mRNA is usually single stranded and the cell detects the double stranded form on mRNA and views it as abnormal. mRNA is broken down by enzymes prevent8ng transcription