Relationship Between Neuroanatomy and Neurology Flashcards

(34 cards)

1
Q

what is diagnosting neurology

A

clinicians make decisions based on clinical diagnoses instead of imaging

Determine location of the lesion from physical examination, history and knowledge about nervous system anatomy/function

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2
Q

are cns lesion types mutually exclusive

A

no

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3
Q

anatomic cns lesion def

A

dysfunction due to structural damage (physical disruption) of CNS

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4
Q

anatomic cns lesion examples

A

stroke, trauma, tumors

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5
Q

physiological cns lesion def

A

dysfunction in absence of obvious anatomic issues. Function is disrupted for less obvious reasons (cells aren’t functioning as expected)

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6
Q

physiological cns lesion ex

A

transient ischemia

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7
Q

symptoms def

A

subjective experience of infliction (what patients report to doctor).

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8
Q

signs def

A

objective measured abnormalities detected by physician. An independent observer can observe.

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9
Q

how are signs and symptoms related

A

signs validate symptoms

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10
Q

what is principle of localized function

A

dif parts of NS have dif functions so damage to an area will affect function of that area

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11
Q

how is the principle of localized function used in diagnostic neurology

A

Can relate signs/symptoms to parts of brain and make predictions based on that

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12
Q

what do negative manifestations result from

A

result from loss of NS function

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13
Q

negative manifestation examples

A

weakness, hemiparalysis, paralysis, sensation loss, memory loss

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14
Q

what do positive manifestations result fro m

A

unexpected inappropriate NS excitation

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15
Q

positive manifestation examples

A

seuizue, spasticity

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16
Q

what are seizures

A

unrestrained neural activity in cortex

17
Q

what do grey matter lesions interfere with

A

function of neuron collections and synapses

18
Q

what type of loss does grey matter lesions cause

A

neuronal loss

19
Q

what type of manifestations do grey matter lesions cause

A

positive and negative

20
Q

what do white matter lesions interfere with

A

signals between neurons

21
Q

what type of loss do white matter lesions cause

22
Q

what type of manifestations do white matter lesions cause

A

only negative manifestations

23
Q

what are syndromes

A

cluster disorders that may have multiple reasons for existing. They are a group of signs/symptoms that are related which suggest a common origin

24
Q

what are the 3 conditions that lead to NS dysfunction

A

destruction of neurons/axons, compression of brain/spinal cord, ventricular/vascular compromise/collapse

25
what is special about compression of brain / spinal cord
Can heal with time depending upon whether cell death happens Transient loss of function
26
what is Ventricular or vascular compromise/collapse
Tumors in regions around ventricles can obstruct blood or CSF flow Blockage of arteries that feed into multiple brain sites can cause cell deathc
27
can ventricular/vascular compromise be reversed
yes if no cell death occurs
28
what is focal pathollogy
signs and symptoms based on single, local isolated CNS lesion
29
example of focal pathology
stroke
30
what is multifocal pathology
damage to CNS at multiple sites Areas still make sense as they are numerous related sites
31
ex of multifocal pathology
MS (demyelination across many areas of CNS in white matter)
32
what is diffuse process pathology
diffuse CNS damage in many places due to toxins/metabolic exposure no rhyme/reason as to why its there
33
factor to consider when determining lesion
age, sex, medical context, time course of illness
34
what is differential diagnosis
list of possibilities based upon data due to synthesis of clinical data