Renal Flashcards

(44 cards)

1
Q

what is often the first sign of any type of illness in neonates?

A
  • poor feeding
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2
Q

3 parameters most significant to assess in children with renal conditions:

A
  • weight
  • I & O
  • blood pressure
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3
Q

other components of the physical exam of the renal system

A
  • abnormal rate and depth of respirations
  • HTN
  • fever
  • FTT
  • signs of circulatory congestion
  • abdominal distention
  • early signs of uremic encephalopathy
  • signs of congenital abnormalities
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4
Q

lab studies and diagnostics for the renal system

A
  • urinalysis
  • urine culture and sensitivity
  • ultrasonography
  • voiding cystourethrogram (VCUG): uses constrast to evaluate their voiding
  • intravenous pyelogram (IVP)
  • cystoscopy
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5
Q

when can we use a urine bag to collect urine?

A

for a urinalysis–don’t need sterile

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6
Q

if you want to do a urine culture, how will you collect it?

A

sterile catheterization

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7
Q

how to get a urine sample for a child <1 yo?

A
  • often use a catheter
    • if can’t obtain with a catheter, then do a suprapubic bladder tap
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8
Q

names of UTIs based on where infection is:

A
  • urethra–>urethritis
  • bladder–>cystitis
  • ureters–>ureteritis
  • kidneys–>pyelonephritis
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9
Q

4 goals of tx for UTIs

A
  • eliminate current infection
  • identify controlling factors
  • prevent systemic spread–>urosepsis
  • preserve renal function
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10
Q

what type of organisms cause UTIs?

A
  • most commonly E. coli and gram negative organisms
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11
Q

contributing factors for UTIs

A
  • urinary stasis
  • urinary reflux
  • poor perineal hygiene
  • constipation–may not allow for full emptying of the bladder
  • pregnancy
  • noncircumcision
  • indwelling catheter placement
  • antimicrobial agents that alter flora of urinary tract
  • tight clothes/diapers
  • bubble baths
  • local inflammation–vaginitis
  • sexual intercourse
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12
Q

peak ages for UTIs

A
  • 2-6 yo and sexually active adolescents
    • higher incidence in females
    • only higher incidence in males when they are newborns
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13
Q

clinical manifestations of UTI

A
  • fever
  • weight loss
  • vomiting, diarrhea
  • frequency
  • urgency
  • chills
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14
Q

in a potty trained child, what would be a sign that they may have a UTI?

A
  • daytime incontinence
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15
Q

diagnostic findings with a UTI

A
  • UA: may reveal hematuria, proteinuria, pyuria
    • urine may be foul smelling and is cloudy with possible strands of mucus
  • culture: reveals growth of bacteria
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16
Q

how to avoid UTIs

A
  • wipe front to back
  • good hydration
  • void right before and right after sexual intercourse
  • avoid bladder irritants: caffeine
  • wear cotton underwear that are not tight, should be well fitting
  • get out of wet underwear/swimsuits quickly
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17
Q

drug therapy for UTIs

A
  • uncomplicated cystitis: short term course of abx
  • complicated UTIs: long term tx
    • TMP-SMX
    • cephalexin
    • gentamycin
  • may beed antispasmodics
  • pyridium: analgesic–>turns urine orange
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18
Q

repeated UTIs

A
  • prophylactic or suppressive abx
  • TMP-SMX administered every day to prevent recurrence or single dose before events likely to cause UTI
19
Q

vesicoureteral reflux (VUR)

A
  • congenital anomalies can cause primary reflux - ureters not inserted normally into bladder
  • secondary reflux is caused by infection and ureterovesicular junction incompetency r/t edema
    • may also be r/t neurogenic bladder and NTDs
  • runs in families
  • graded 1-5:
    • 5 is worst
20
Q

clinical manifestations of VUR

A
  • dysuria
  • urinary frequency, urgency, hesitancy
  • urinary retention
  • cloudy, dark, blood tinged urine
  • recurrent UTIs
21
Q

diagnostic findings with VUR

A
  • RBCs or pyuria noted in UA
  • IVP, VCUG, or cystoscopy may reveal structural abnormalities
22
Q

tx for VUR

A
  • nonsurgical:
    • deflux injection - gel used in endoscopic injections
      • gel is injected around the ureter opening to create a valve and to make the backflow of urine into the kidneys more difficult
      • requires anesthesia
  • surgical:
    • detach ureter and reinsert at correct angle
      • use a stent
      • need 24 hr hospital stay
23
Q

nephrotic syndrome

A
  • complex of symptoms characterized by:
    • proteinuria
    • hypoalbuminemia
    • hyperlipidemia
    • altered immunity and edema
  • etiology unknown
    • but minimal change nephrotic syndrome is most common
    • can also be secondary to SLE, DM, sickle cell anemia
24
Q

pathology of nephrotic syndrome

A
  • somehow there is inc permeability to protein usually due to some damage to the glomerulus, so the protein leaks out and albumin comes out in the urine
  • what causes fluid shift from intravascular space to interstitial space?
    • hypoalbuminemia decreases the colloid osmotic pressure in the capillaries, as a result the hydrostatic pressure exceeds the colloid osmotic pressure and fluid accumulates in the interstitial spaces and the body cavities–>3rd spacing occurs
  • what does the change in intravascular vol stimulate?
    • RAAS system and secretion of ADH and aldosterone–>body tries to retain fluid
    • tubular reabsorption of sodium and water inc in an attempt to inc intravascular volume
25
clinical manifestations of nephrotic syndrome
* periorbital, pedal, and scrotal edema that progresses to generalized edema * generalized edema may progress to resp distress * weight inc--\>b/c retaining fluids * dec urine output * possible pleural effusion--\>fluid has to go somewhere * pallor anorexia * fatigue * abdominal pain * diarrhea * _BP may be normal or even slightly dec_--\>b/c intravascular volume is depleted * high urine SG
26
diagnostic findings of nephrotic syndrome
* UA: * marked proteinuria, * hyaline casts, * few RBCs, * inc specific gravity * serum protein level is markedly decreased * esp the albumin level
27
tx for nephrotic syndrome
* during edema phase--child limited to quiet activity * during remission--activity is not restricted * acute and recurrent infections are treated with appropriate abx and efforts are made to minimize the risk of injury * corticosteroid--started as soon as the diagnosis has been established * 2 mg/kg in divided BID doses * 3 mos of therapy * course of therapy: usually not immediate change, but know they are improving when pt starts to diurese * remember to never d/c steroids abruptly * children with nephrotic syndrome often relpase 1-3 times/year
28
diet for nephrotic syndrome
* salt restriction necessary when massive edema and when taking corticosteroids * is water restricted? * seldom but may be necessary when have severe edema * protein? * not necessarily beneficial to inc protein in diet * should restrict protein if have azotemia and renal failure
29
acute glomerulonephritis (GN)
* most are post streptococcal * may be distinct entity or manifestation of SLE, sickle cell
30
clinical manifestations of acute GN
* _HTN_: due to inc ECF * pallor * irritability * fatigue * lethargy * periorbital and generalized edema--not as obvious as nephrotic syndrome * weight gain * electrolyte imbalance * oliguria and hematuria--cola colored urine * CVA tenderness * anorexia
31
diagnostic findings with GN
* UA: RBCs, casts, WBCs, and protein * (inc amt of protein = inc severity of renal dz) * serum chemistry: * elevated BUN, Cr, ESR, and anti streptolysin O titer (ASO--shows if current or post strep infection) * serum complement level (CS) is dec initially but returns to normal 8-10 weeks after onset GN
32
acute post streptococcal GN (APSG)
* noninfectious renal dz (autoimmune) * onset 5-12 days after another infection * often group A beta hemolytic strep * most common in children 6-7 yo * older kids than nephrotic syndrome * uncommon in children under 2
33
nursing mgmt of APSG
* manage edema: daily weights, accurate I/O, daily abdominal girth * nutrition: * low sodium: moderate restriction with HTN or edema * low to moderate protein * potassium containing foods restricted during the period of oliguria * susceptibility to infections * bed rest is not necessary--although most kids will restrict activity b/c of malaise
34
hypospadias
* urethral opening below the glans penis or anywhere along ventral surface of penile shaft * can be assoc with undescended testes and inguinal hernias * pathology results from failure of the urethral folds to fuse completely over the ureteral groove
35
post op care for hypospadias or epispadias
* care of indwelling catheter * no baths until catheter removed * instruct to gently cleanse around tip of penis and catheter * encourage liquids * analgesia as needed
36
acute renal failure (ARF)
* kidneys suddenly unable to regulate the volume and composition of urine * esp if dehydrated * not common in children * principle feature is oliguria * assoc with azotemia, metabolic acidosis, and electrolyte disturbances * most common cause is transient renal failure resulting from severe dehydration * usually reversible * mgmt: aimed at minimizing complications * assess for changes in V/S, U/O
37
complications of ARF
* hyperkalemia: restrict potassium * HTN * anemia * sz * hypovolemia * cardiac failure w/ pulmonary edema
38
chronic renal failure (CRF)
* begins when diseased kidneys cannot maintain normal chemical structure of body fluids * clinical syndrome called uremia
39
potential causes of CRF
* congenital renal and urinary tract malformations * VUR assoc with recurrent UTIs * chronic pyelonephritis * chronic GN
40
what are the 3 types of dialysis?
* hemodialysis * peritoneal dialysis * hemofiltration
41
hemodialysis
* very time consuming * requires creation of a vascular access and special dialysis equipment * best suited for kids who can be brought to facility 3 times per week for 4-6 hrs * achieves rapid correction of fluid and electrolyte abnormalities * assess AV fistual: auscultate for bruit and palpate for thrill
42
peritoneal dialysis
* abdominal cavity acts as semipermeable membrane for filtration * can be managed at home in some cases * warmed solution enters peritoneal cavity by gravity * remains for period of time before removal * weigh client before and after procedure to see how much fluid taken off
43
continuous venovenous hemofiltration
* uses technique for ultrafiltration of blood continuously at a very slow rate * works with the fluid overload in portop period * successful alternative for critically ill children who might not survive rapid volume changes of hemodialysis of PD * best type of dialysis if client is hemodynamically unstable * done in ICU
44
transplantation
* have to match HLA antigens * 7 HLAs--more that match, the better the chance to prevent rejection * cna be from living or cadaver donor * primary goal: long term survival of grafted tissue * will be on immunosuppresant therapy