Renal Flashcards
(44 cards)
what is often the first sign of any type of illness in neonates?
- poor feeding
3 parameters most significant to assess in children with renal conditions:
- weight
- I & O
- blood pressure
other components of the physical exam of the renal system
- abnormal rate and depth of respirations
- HTN
- fever
- FTT
- signs of circulatory congestion
- abdominal distention
- early signs of uremic encephalopathy
- signs of congenital abnormalities
lab studies and diagnostics for the renal system
- urinalysis
- urine culture and sensitivity
- ultrasonography
- voiding cystourethrogram (VCUG): uses constrast to evaluate their voiding
- intravenous pyelogram (IVP)
- cystoscopy
when can we use a urine bag to collect urine?
for a urinalysis–don’t need sterile
if you want to do a urine culture, how will you collect it?
sterile catheterization
how to get a urine sample for a child <1 yo?
- often use a catheter
- if can’t obtain with a catheter, then do a suprapubic bladder tap
names of UTIs based on where infection is:
- urethra–>urethritis
- bladder–>cystitis
- ureters–>ureteritis
- kidneys–>pyelonephritis
4 goals of tx for UTIs
- eliminate current infection
- identify controlling factors
- prevent systemic spread–>urosepsis
- preserve renal function
what type of organisms cause UTIs?
- most commonly E. coli and gram negative organisms
contributing factors for UTIs
- urinary stasis
- urinary reflux
- poor perineal hygiene
- constipation–may not allow for full emptying of the bladder
- pregnancy
- noncircumcision
- indwelling catheter placement
- antimicrobial agents that alter flora of urinary tract
- tight clothes/diapers
- bubble baths
- local inflammation–vaginitis
- sexual intercourse
peak ages for UTIs
- 2-6 yo and sexually active adolescents
- higher incidence in females
- only higher incidence in males when they are newborns
clinical manifestations of UTI
- fever
- weight loss
- vomiting, diarrhea
- frequency
- urgency
- chills
in a potty trained child, what would be a sign that they may have a UTI?
- daytime incontinence
diagnostic findings with a UTI
- UA: may reveal hematuria, proteinuria, pyuria
- urine may be foul smelling and is cloudy with possible strands of mucus
- culture: reveals growth of bacteria
how to avoid UTIs
- wipe front to back
- good hydration
- void right before and right after sexual intercourse
- avoid bladder irritants: caffeine
- wear cotton underwear that are not tight, should be well fitting
- get out of wet underwear/swimsuits quickly
drug therapy for UTIs
- uncomplicated cystitis: short term course of abx
- complicated UTIs: long term tx
- TMP-SMX
- cephalexin
- gentamycin
- may beed antispasmodics
- pyridium: analgesic–>turns urine orange
repeated UTIs
- prophylactic or suppressive abx
- TMP-SMX administered every day to prevent recurrence or single dose before events likely to cause UTI
vesicoureteral reflux (VUR)
- congenital anomalies can cause primary reflux - ureters not inserted normally into bladder
- secondary reflux is caused by infection and ureterovesicular junction incompetency r/t edema
- may also be r/t neurogenic bladder and NTDs
- runs in families
- graded 1-5:
- 5 is worst
clinical manifestations of VUR
- dysuria
- urinary frequency, urgency, hesitancy
- urinary retention
- cloudy, dark, blood tinged urine
- recurrent UTIs
diagnostic findings with VUR
- RBCs or pyuria noted in UA
- IVP, VCUG, or cystoscopy may reveal structural abnormalities
tx for VUR
- nonsurgical:
- deflux injection - gel used in endoscopic injections
- gel is injected around the ureter opening to create a valve and to make the backflow of urine into the kidneys more difficult
- requires anesthesia
- deflux injection - gel used in endoscopic injections
- surgical:
- detach ureter and reinsert at correct angle
- use a stent
- need 24 hr hospital stay
- detach ureter and reinsert at correct angle
nephrotic syndrome
- complex of symptoms characterized by:
- proteinuria
- hypoalbuminemia
- hyperlipidemia
- altered immunity and edema
- etiology unknown
- but minimal change nephrotic syndrome is most common
- can also be secondary to SLE, DM, sickle cell anemia
pathology of nephrotic syndrome
- somehow there is inc permeability to protein usually due to some damage to the glomerulus, so the protein leaks out and albumin comes out in the urine
- what causes fluid shift from intravascular space to interstitial space?
- hypoalbuminemia decreases the colloid osmotic pressure in the capillaries, as a result the hydrostatic pressure exceeds the colloid osmotic pressure and fluid accumulates in the interstitial spaces and the body cavities–>3rd spacing occurs
- what does the change in intravascular vol stimulate?
- RAAS system and secretion of ADH and aldosterone–>body tries to retain fluid
- tubular reabsorption of sodium and water inc in an attempt to inc intravascular volume