Renal Flashcards
1
Q
What is the histology of renal Ca?
A
Clear cell renal cell carcinomas (ccRCC)
Papillary renal cell carcinomas (pRCC)
Chromophobe renal cell carcinomas (crRCC)
2
Q
What are the symptoms of renal Ca?
A
Haematuria Loin pain Abdo mass (rare) Anorexia Malaise Weight loss
3
Q
How should suspected renal Ca be investigated?
A
BP (increased = increased renin)
FBC (polycythaemia = increased EPO)
ESR
U+E
ALP (?bony mets)
Urine cytology
Imaging: US, CT, MRI, CXR (cannon ball mets)
4
Q
Outline the management of renal Ca
A
Radical nephrectomy
RCC generally DXT/chemo resistant
Biologics = angiogenesis-targeted agents (sunitinib)
TCC = nephro-ureterectomy
5
Q
What is the aetiology of RCC?
A
Smoking
Obesity
Dialysis
