Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Renal > Renal Clearance And GFR > Flashcards

Renal Clearance And GFR Flashcards

1
Q

What is clearance

A

Rate at which substances are removed from plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is renal Clearance

A

Volume of plasma completely cleared of a substance by the kidneys per unit time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does high rental clearance means

A

High removal of substances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the equation for renal clearance

A

C = (urine concentratiin of substance * urine flow rate ) / plasma concentration of substance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Is albumin filtered across glomerular capillaries

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the renal clearance of albumin

A

0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Renal clearance of glucose

A

0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why is Renal clearance of glucose zero

A

Glucose is completely reabsorbed back into the bloodstream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What substances clearance measures the GFR Because it is neither a reabsorbed nor secreted after being filtered

A

Inulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the glomerular marker

A

Inulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the clearance ratio formula

A

Clearance of substance / clerance of inulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does a clearance ratio of one means

A

Means that the substance is also a glomerular marker so neither reabsorbed not secreted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does a clearance ratio inferior to one means

A

the substance is either not filtered or it is filtered and then reabsorbed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does the clearance ratio of more than one means

A

It means that the substance is filtered and then secreted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is an ultra filtrate

A

Fluid that is filtered from blood at the Bowman space and is composed of water , small solutes of blood but no proteins and blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What determines the rate of glomerular filtration and characteristics of the glomerular filtrate

A

The physical characteristics of the glomerular capillary walls

17
Q

What do you find in the endothelium of the glomerular capillary

A

Pores 70-100nm in diameter

18
Q

What are the role of pores in the endothelium of the glomerular capillary

A

To allow filtration across this layer of fluids dissolved solute’s in plasma proteins and block blood cells

19
Q

What is the most significant barrier of the glomerular capillary

A

The multilayered basement membrane because does not allow filtration of plasma proteins

20
Q

What specialized so do you find in the epithelium of the glomerular capillary

A

Podocytes

Filtration slits

21
Q

Is inulin endogenous

A

No must be injected iv

22
Q

LWhat is the closest substance to the perfection of inulin As a glomerular marker

A

Creatinine

23
Q

Why is creatinine not so much perfect as in

A

One part of it is secreted so clearance slightly over estimates the GFR

24
Q

What is the positive side of creatinine

A

Endogenous substance so no need for injection

Renal (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions