Renal Disease Flashcards Preview

Clinical Biochemistry > Renal Disease > Flashcards

Flashcards in Renal Disease Deck (12):
1

Function of the kidneys?

Production of blood
Production of urine
Hormone synthesis
Reabsorption of water

2

Blood in the urine?

Damage

3

Dipstick testing

Easy to use

4

Urea

Synthesised in the liver
By product of deamination of amino acids
Diffuse freely through membranes
Urea levels can be affected in a number of situations

5

What is Creatinine?

By product of muscle metabolism

6

The ranges of urea?

2.5-8 mmol/L

7

The functional unit in the kidney?

The Nephron

8

What is the glomerular function?

Fluid maintenance
Electrolyte & pH balance

9

What affects the glomerulus?

Blood pressure
Number and area covered by nephrons

10

Estimation of the glomerular filtration rate?
GFR

Accepted as the best overall measure of kidney function
A decrease in GFR--->renal failure
Used to monitor progression

11

How do you calculate GFR?

GFR x (PS) = (US) x V
Then
GFR= (US)x V/ (PS)

12

Proteineria is an indicator of what?

Glomerular function
They indicate damage to the basement membrane