Renal function Flashcards
(2 cards)
Summary of RF, differentiate between G+T
Kidney function - Maintain homeostasis via regulation of e-, excrete TW, hormones e.g aldosterone
2 sections G+T
GFR, rate of blood filtered through the glomeruli, depends on renal flow + BP, factors affecting: BF, obstruction, retain WP
Used to measure clearance tests which is used to measure creatinine in urine, conc used 2M GFR
EF are: Age, sex weight… RR 60/90ml/min
Elevation suggests kidney DF
Serum urea: elevated = dec GFR, GTI can elevate
Measure plasma b2 microglobulin: inc malig risk of infl disease
Tubular, found in nephron, filters blood and maintains homestasis
Disorders may be inherited or from toxin exposure,
Tests: urinalysis: Studies visual appearance, through DST and exam… can measure glucose, ketones and proteins pH… Normal Col - amber
Cloudy may suggest alkylation or dehydration
Dipstick identifies specific substances, acidic = UTI
Diabetic ketoacidosis could cause low pH, hematuria, proteinuria = kidney or heart failure
Glycosia maybe funconi syndrome
3 causes of ARF
Involves dec in function of hours or days, 3 stages
Prerenal - dec in BF to kidney caused by hypotension or cardiac failure
Intrinsic – Damage to kidneys, caused by B2, septic shock or microvascular disease
Postrenal - Caused by renal obstruction = inc hydrostatic pressure
Identified through biochemical tests
Serum urea - >10:1 , urea plasma osmoalilty >1.5
Main cause: Dec BF, septic shock BL, medical overdose through aspirin or ibuprofen
Symptoms: Tiredness: nausea, vomiting, dec urine, muscle weakness
