Renal Histology Flashcards
(25 cards)
in the glomerulus, there are two layers of epithelium, the _____ and the ______.
parietal epithelium
visceral epithelium
the endothelial cells that make up the capillaries in the glomerulus are what kind of capillary?
fenestrated endothelial cells
the visceral epithelium in the glomerulus is made up of what kind of cells?
podocytes
podocytes have _____ that stretch out and attach to the basement membrane
pedicles
from the capillary lumen to bowman’s space, what are all the layers you have to get through?
first is the endothelial cells, then the lamina rara interna, then the lamina densa, then the lamina rara externa
the lamina densa filters by ____ and the lamina rara filters by ____
size, charge
the distal convoluted tubule comes back around and goes right in between the _______ and _____. The cells that come in contact with this juxtaglomerular area are thickened and are named the _____
afferent and efferent arterioles
macula densa
what is the function of the macula densa cells?
they are osmosensors, sensing NaCl levels
the cells located between the macula densa and afferent arteriole are called ____
mesangial cells
what is the function of mesangial cells?
they are specialized contractile cells that control blood flow
what is the function of juxtaglomerular cells?
they are granular cells that secrete renin
Label
A: distal convoluted tubule
B: macula densa
C: juxtaglomerular cells
D: afferent arteriole
label
A: justaglomerular cells
B: macular densa
C: distal convoluted tubule
how do you tell the difference between distal tubule and proximal tubule?
the proximal tubule will have a thicker cell lining and will have a brush border, while the distal tubule cells are more flat/thin and do not have a brush border. Distal tubules are also associated with the juxtaglomerular apparatus
this is right in the renal papillae area. What kind of epithelium is this?
transitional epithelium, or uroepithelium
it lines the renal pelvis, ureter, and bladder
what is this slide showing?
the collecting ducts which would be found in the medullar of the kidney
what kind of cells line the collecting ducts?
cuboidal/columnar epithelial cells
what are the two kinds of cells that line the collecting ducts? How can you tell them apart?
principal cells and intercalated cells
prinipal cells are more clear and buldgy according to MATYAS
What is the function of principal cells?
what is the function of intercalated cells?
sodium and water regulation thru ADH and aldosterone
acidification of the urine, H+ ions
label from top to bottom
bowmans capsule
masangial cells
macula densa
proximal tubule (thicker and with brush border)
when the bladder is full (not contracted), the transitional epithelial cells appear_____
when the bladder is empty (contracted), the transitional epithelial cells appear ____
squished and stretched
larger, more bulbus
the bladder wall contains____ which allows it to contract
smooth muscle
the ureter has 4 layers just like the GI tract which are:
tunica adventitia, tunica muscularis, submucosa, and mucousa
