Renal Osteodystrophy Flashcards
(6 cards)
1
Q
Lab characteristic of this begins with:
A
Hyperphosphatemia
2
Q
Hyperphosphatemia does what do calcium levels
A
drops it, as the nephron attempts to reduce phosphate load
3
Q
how does PTH respond to hypocalcemia
A
Hyper-PTH
- can cause parathyroid hyperplasia and adenomas if untreated
4
Q
Renal disease affects vitamin D activity by:
A
deficient activity of 1-alpha-hydroxylase, which prevents activation of 25-hydroxy vitamin D to 1,25-dihydroxy-D
5
Q
Clinical manifestations of hypocalcemia
A
- muscle cramps
- seizures
- abdominal pain
- dyspnea
- mental status changes
- Trousseu’s sign
- Chvostek’s sign
6
Q
Brown Tumor
A
resembles a giant cell tumor of bone which occurs in the setting of hyperparathyroidism
