Renal Pathology part 1 Flashcards Preview

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Flashcards in Renal Pathology part 1 Deck (64)
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In glomerulopathy, sub-epithelial complexes with resultant host responses can result in

a thickened basement membrane apearance by LM--membranous nephropathy


In humans, primary membranous nephropathy is

an autoimmune disease caused by Abs to endogenous tissue componenets


Secondary forms of membranous nephropathy can be experimentally induced by

drugs (mercuric chloride) and graft vs host disease


In some situations of membranous nephropathy

there may be uncontrolled B cell activation leading to the production of autoantibodies that react with renal Ags