Renal Shit I Dont Know Flashcards Preview

CPR > Renal Shit I Dont Know > Flashcards

Flashcards in Renal Shit I Dont Know Deck (15)
Loading flashcards...
1
Q

What is B cell lymphoma associated with?

A

Membranoproliferative GN

2
Q

What does type I MPGN occur exclusively in?

A

Adults

3
Q

What else is MPGN I seen in?

A

Hep C, SLE, and malignancies

4
Q

What pattern does MPGN tend to be?

A

Nephritic and nephrotic

5
Q

What 3 things is MPGN I associated with?

A
  1. ) SLE
  2. ) Malignancies
  3. ) Hep C
6
Q

What does type II MPGN activate?

A

alternative complement

7
Q

Describe the histo findings of MPGN

A

Mesangial proliferation with involvement of the BM

8
Q

LM of MPGN

A

Hypercellularity of the mesangium with a double contour and tram track appearance

9
Q

EM of MPGN

A

Subendothelial dense deposits

10
Q

IF of MPGN

A

Granular pattern with IgG, IgM, and C3

11
Q

What is secondary MPGN almost always?

A

Type I MPGN

12
Q

What is type II MPGN associated with?

A

C3NeF

13
Q

What is the morphology of type II MPGN?

A

mesangial proliferative pattern

14
Q

What is the EM of T2 MPGN?

A

electron dense ribbon of material

15
Q

What is the IF of T2 MPGN?

A

C3 present in irregular granular or linear foci