Renal, Urology, Gynae, Breast Flashcards
(121 cards)
Which testosterone blood test should be done for ED?
Free testosterone
Testosterone bound to SHBG which increases with age so poor correlation with total testone and symptoms
What is the definition of recurrent UTI?
Two or more UTI’s within 6 months
Name 3 possible reasons to consider a referral for bladder ca?
Unexplained haematuria over age 45 (no UTI or persisting after UTI)
NVH over 60 WITH dysuria or raised WCC
(Both 2ww)
Non-urgent referral for anyone over 60 with recurrent or persistent UTI’s (2 or more in 6 months)
How is interstital cystitis managed? (Name 3 steps)
Simple (paracetamol + nsaid)
2) + Oxybutynin
3) + Amitriptyline (off label, with specialist)
Name 4 groups of drugs which can cause ED?
Antidepressant
Antihypertensive
Diuretics
Ranitidine
Cardiac drugs
Recreational drugs
What are the PSA cut offs for prostate cancer?
40-49- > 2.5
50-59 - > 3.5
60-69 - > 4.5
70-79 - > 6.5
If above this refer on 2ww for cancer
Who should PSA be offered to and what should not be done before testing?
Suspected prostate Ca/ anyone over 50 who requests one
No UTI or urology intervention in last 6 weeks
No vigorous exercise or ejactualation in last 48hrs
Acute prostatitis:
a) Classic presentation
b) Management
a) Fever, dysuria, low back and perineal pain
b) Ciprofloxacin or ofloxacin for 14 days (send MSU also)
How may radiation induced enteropathy present? How is it investigated?
Common complication of prostate cancer treated with radiotherapy.
Presents diarrhoea, urgency, steatorrhoea, bloating, rectal pain
Investigate with sigmoidoscopy
A 28-year-old lady has a positive leucocyte esterase and nitrites on a routine urine dipstick test. She is asymptomatic.
What is the SINGLE MOST appropriate management option?
Send urine MCS
- Delay starting antibiotics til results available
(If symptomatic and either leuk or nitrates then treat straight away - here not treated as asymptomatic)
How should symptomatic, partially retractile phimosis be managed?
1st: Mod to potent steroid with regular gentle retraction in the bath or shower
2nd - Circumcision if this fails
What is the biggest cancer risk following external beam radiotherapy for prostate ca?
New primary rectal Ca
Also radiation induced enteropathy
What tumour markers are associated with non-seminomatous germ cell tumour?
AFP
hCG
What tumour markers are associated with testicular seminoma’s?
None
(AFP and hCG are associated with non-seminomatous)
What potential risk should you be aware of for patients on metformin when considering contrast requiring investigation?
Lactic acidosis
What is the gold standard test to confirm nephrotic syndrome?
24 hour urine collection for protein: creatinine ratio
A spot test for protein:creatinine ratio provides a reasonable level of confirmation and is practical to request in primary care. However, a 24-hour urine collection for protein:creatinine ratio remains the gold standard.
In the context of UTI’s in children, name 3 indications for renal tract USS?
- When should the USS be performed
Typical infection in under 6 month olds (to be performed within 6 weeks)
All children over 6m with recurrent UTI’s (performed within 6 weeks)
All children with atypical infection (performed during current illness)
- Raised creatanine/ sepsis/ poor flow
- Any non e.coli infection
- Any doesn’t respond within 48 hours
What is the definition of recurrent UTI in children?
3 or more UTI’s during childhood
2 or more UTI’s if one or more of them were upper/ pyelonephritis
What are the indications for a DMSA in children with UTI’s?
All children aged under 3 years with atypical or recurrent UTI.
All children aged 3 years or over with recurrent UTI.
(Usually after USS renal tract and only done in secondary care)
Alkalinising agents (such as potassium citrate) can reduce the effectiveness of which SINGLE antibiotic?
Nitrofurantoin
(Advise women to avoid)
What is the blood pressure target for patients with polycystic kidney disease? When may this be lower?
Which agent is used first line?
130/80 mm Hg
- Lower if proteinuria (>1g/day)
ACEI are first line
Given two examples of anticholinergics which may be used to control urinary symptoms?
Oxybutanin
Tolterodine
Intersistial cystitis:
a) 3 presenting symptoms
b) Classic cystoscopy finding?
a) Abdominal pain + urgency + frequency
b) Hunner lesions
A patient is being started on goserelin (GnRH antagonist) - what is the most concerning initial side effect and what is done to prevent this?
Tumour flare up (initial 1-2 week lack of testosterone can make the tumour swell - concern RE spinal cord compression etc)
Anti-androgen treatment (cyproterone) is started 3 days before until 3 weeks after to mitigate this