Renin release Flashcards Preview

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Flashcards in Renin release Deck (6):
1

What 3 factors trigger release of renin?

1) sympathetic stimulation
2) renal hypoperfusion
3) decreased sodium delivery to distal tubule (macula densa)

2

What are 3 factors that cause renal hypo-perfusion?

a) decreased circulating volume
b) low cardiac output (usually high volume state)
c) renal artery stenosis

3

What is the effect of diuretics on renin?

increase renin release - "because of decreased renal blood flow"......

4

What is the effect of clonidine on renin release?

inhibits it because less sympathetic stimulation of B1 receptors on juxtoglomerular cells

5

What is the effect of arteriolar vasodilators on renin release?

slightly increased because arteriolar dilation reduced total peripheral resistance which causes slight hypoperfusion of kidneys....

6

ACE inhibtors and ATII receptor blockers do what do renin release?

slight increase due to vasodilation and slight renal hypopersion