Repiratory Patho Flashcards

(39 cards)

1
Q

Infectious diseases
Upper

A

Upper Respiratory Infection (URI)

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2
Q

Infectious diseases
Lower

A

Bronchiolitis (RSV)
Pneumonia
SARS/MERS
TB
Fungal diseases

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3
Q

Obstructive lung diseases

A

Cystic fibrosis
Cancer
Aspiration pneumonia
Asthma
Emphysema
Chronic bronchitis

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4
Q

Obstructive lung diseases means

A

Cannot get the air out of the lungs

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5
Q

Restrictive lung diseases

A

Chest wall abnormalities
Connective tissue abnormalities

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6
Q

Restrictive lung diseases means

A

Cannot get the air into the lungs

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7
Q

Vascular disorders

A

Pulmonary edema
Pulmonary embolism

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8
Q

Expansion disorders

A

Atelectasis
Pleural effusion
Pneumothorax

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9
Q

UPPER RESPIRATORY INFECTION

A

Acute inflammatory process that affects mucus membrane of the upper respiratory
tract

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10
Q

ex of UPPER RESPIRATORY INFECTION

A

Includes one or more of the following problems
Rhinitis
Pharyngitis
Laryngitis
Sinusitis

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11
Q

UPPER RESPIRATORY INFECTION Symptoms

A

Low-grade fever, malaise, sore throat, discharge

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12
Q

UPPER RESPIRATORY INFECTION Etiology

A

> 200 different viruses have been implicated
Can get secondary bacterial infection

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13
Q

LOWER RESPIRATORY INFECTIONS

A

Pneumonia
6th leading cause of death in US; incidence
highest in elderly
Etiology
Common bacteria: pneumococcus
Viral most common in children
Community acquired:
Pneumococcus
Nosocomial
Pseudomonas, MRSA
Fungi – Coccidiomycosis (Valley Fever)
Trauma to lungs
Foreign body aspiration

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14
Q

TUBERCULOSIS (TB)

A

TB incidence began increasing in the late 1980’s
HIV population → opportunistic infections
Increase in low socio-economic and homeless population
Doctor complacency
Drug company complacency
Patient non-compliance
Led to bacterial resistance
Mycobacterium tuberculosis is quite resistant to eradication and can live in an inactive
form for long times
Example = dried sputum
Very contagious via air droplets

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15
Q

TB Signs and symptoms

A

fever, chills,
night sweats, productive cough, loss of appetite,
weight loss, and fatigue.

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16
Q

LUNG CANCER

A

Broadly classified into two types
Non-small cell
Small cell
Based upon the microscopic appearance of the tumor

17
Q

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

A

Irreversible progressive obstruction of air flow in lungs
Includes
Chronic Bronchitis
Bronchiectasis
Emphysema
Air goes into lungs easily but unable to come out; air trapped in distal alveoli,
causing hyperinflation & over-distension

18
Q

Chronic Bronchitis (COPD)

A

Chronic inflammation of mucus membrane
Defined as a chronic mucus producing cough
most days of the month, three months of the
year for two successive years without other
underlying disease to explain the cough
Hyperplasia of mucosa & destruction of cilia
Results in a chronic, deep, productive cough
Long term smoking, certain environmental
factors such as textile dust fibers

19
Q

Chronic Bronchitis (COPD) symptoms

A

Productive cough, SOB, wheezing

20
Q

Bronchiectasis (COPD)

A

Permanent, irreversible dilation & distortion of
bronchi
Complication of cystic fibrosis
TB
Takes years to develop
Primarily in the lower lobes

21
Q

Bronchiectasis (COPD) symptoms

A

Chronic productive cough

22
Q

COPD Emphysema

A

Destructive disease of alveolar septa
Permanent & irreversible
Non-functioning alveoli
Chest x-ray shows: translucent appearing
lungs, flattened diaphragm, &
cardiomegaly
Clubbed fingers
Increased lung compliance
Decreased lung elasticity

23
Q

ASTHMA

A

Chronic inflammatory disorder
associated with airway hyper-
responsiveness leading to recurrent
episodes
Often reversible airflow limitation
Prevalence increasing in many
countries, especially in children

24
Q

ASTHMA triggers

A

Triggers
Allergens
Exercise (EIA)
Especially in cold weather
Air pollutants
Occupational factors
Respiratory infections
viral
Chronic sinus and nose problems
Drugs and food additives
NSAIDs, ß-blockers, ACEi, dye, sulfites
Gastro-esophageal reflux disease (GERD)
Psychological factors
stress

25
RESTRICTIVE LUNG DISEASES
Characterized by decreased airway compliance Two groups of diseases Abnormalities of chest wall which limits lung expansion Includes: Kyphosis Scoliosis Polio ALS Muscular dystrophy Burn scar Disease affecting lung tissue that provides supporting framework Includes: Occupational diseases (pneumoconiosis) Idiopathic pulmonary fibrosis (autoimmune disease) Pulmonary edema Acute respiratory distress syndrome (ARDS)
26
Pulmonary edema
Fluid collection (edema) in all lung tissues Affects gas exchange Affects lung expansion Key = pulmonary capillary pressure increases & fluid moves into alveoli Capillaries rupture & get bloody sputum (hemoptysis) True medical emergency
27
Pulmonary edema Etiology
Left sided heart failure Inhalation of toxic gases Lymphatic blockage (e.g. from tumor)
28
VASCULAR DISORDERS
Pulmonary Emboli Clot of foreign matter that occludes artery in pulmonary system Size of embolus & general health of patient determine degree of damage and amount of symptoms Thrombus (most common) Air, fat, bacteria, tissue Large bone fractures can result in fat emboli Risk increased by CHF, lung disease, stasis with varicosities 90% originate from deep veins (primarily in leg)
29
EXPANSION DISORDER
Atelectasis Collapsed pulmonary tissue Results in degrees of hypoxia Causes: Pleural effusion Obstruction of the bronchial tree Obstruction leads to absorption atelectasis Compression atelectasis
30
PLEURAL EFFUSION
Pathophysiology = fluid separates the two pleural membranes Lungs do not expand properly during inspiration since there is no cohesion between ---- lung/visceral pleura/ parietal pleura Types: Transudates = hydrothorax Blood = hemothorax Pus = empyema
31
PNEUMOTHORAX
Collection of air or gas in pleural cavity resulting in collapse (either partial or full) of lung Spontaneous pneumothorax Open pneumothorax --- usually secondary to trauma Tension pneumothorax
32
COR PULMONALE
Pulmonary heart disease Disease of the RIGHT side of the heart from pulmonary hypertension Does not include pulmonary hypertension as a result of LEFT sided heart failure Causes COPD Pulmonary fibrosis Persistent atelectasis PE Pulmonary vascular sclerosis The right ventricle develops hypertrophy and over time the right ventricle is unable to maintain cardiac output
33
Obstructive lung diseases: cycstic fibrosis
a genetic disease that causes thick, sticky mucus to build up in the body, leading to breathing and digestion problems
34
Obstructive lung diseases: Cancer
Broadly classified into two types Non-small cell Small cell Based upon the microscopic appearance of the tumor, i.e. Chronic obstructive pulmonary disease (COPD) is a significant risk factor for lung cancer
35
Obstructive lung diseases: Aspiration pneumonia
occurs when oral or gastric contents are aspirated into the lungs, leading to infection. It often results from impaired swallowing or protective airway reflexes
36
Obstructive lung diseases: Asthma
Chronic inflammatory disorder associated with airway hyper- responsiveness leading to recurrent episodes Often reversible airflow limitation Prevalence increasing in many countries, especially in children
37
Obstructive lung diseases: COPD Emphysema
Destructive disease of alveolar septa Permanent & irreversible Non-functioning alveoli Chest x-ray shows: translucent appearing lungs, flattened diaphragm, & cardiomegaly Clubbed fingers Increased lung compliance Decreased lung elasticity
38
Obstructive lung diseases: Chronic Bronchitis (COPD
Chronic inflammation of mucus membrane Defined as a chronic mucus producing cough most days of the month, three months of the year for two successive years without other underlying disease to explain the cough Hyperplasia of mucosa & destruction of cilia Results in a chronic, deep, productive cough Long term smoking, certain environmental factors such as textile dust fibers
39
What is SARS/MERS
SARS (severe acute respiratory syndrome) and MERS (Middle East respiratory syndrome) are serious infectious respiratory diseases that are caused by members of a class of viruses known as coronaviruses