Reproductive Flashcards
(133 cards)
What is acute bacterial prostatitis?
A severe infection involving the prostate that may cause significant systemic upset.
What are the risk factors for acute bacterial prostatitis?
- Age → Most common in men over 50 years old
- STI
- UTI
- Indwelling catheter
- Post-biopsy
What are the signs of acute bacterial prostatitis?
- Tender, hot, swollen prostate(on digital rectal exam)
- Palpable bladder(if urinary retention)
- Tachycardia
- Pyrexia
What are the symptoms of acute bacterial prostatitis?
- Dysuria
- Urinary frequency
- Urinary retention
- Hesitancy
- Post-micturition dribbling
- Straining
- Perineal, rectal or pelvic pain
- Back pain
- Fevers
- Myalgia
- Malaise
What are the investigations of acute bacterial prostatitis?
- Digital rectal exam
- Urine dipstick
- FBC
- U&Es
- CRP
- Cultures (urine, semen, blood)
- STI testing
- Imaging - MRI, TRUSS (trans-rectal ultrasound scan)
What is the management for acute bacterial prostatitis?
- Antibiotics: courses typically 14 days
- First line:Oral ciprofloxacin or ofloxacin
- Second line:Oral levofloxacin or co-trimoxazole
- IV antibiotics: for patients with significant infection under microbiology guidance.
What are the complications of acute bacterial prostatitis?
- Acute urinary retention
- Epididymitis
- Chronic prostatitis
- Prostatic abscess
What is chronic prostatitis?
Chronic prostatitis is characterised by > 3 months of urogenital pain, often associated with LUTS or sexual dysfunction.
What are the two types of chronic prostatitis?
- Chronic prostatitis/chronic pelvic pain syndrome:clinical features of chronic prostatitis in the absence of an identifiable bacterial infection.
- Chronic bacterial prostatitis:relatively uncommon, accounting for around 10% of patients with chronic prostatitis.
What are the risk factors for chronic prostatitis?
- Those with underlying urinary tract abnormalities are at greater risk.
- Men with HIV are at risk of a greater breadth of infection.
- Rarely STI’s are the infective agent.
What are the clinical manifestations of chronic prostatitis?
- Urogenital pain
- Urinary symptoms
- Hesitancy
- Dysuria
- Frequency
- Sexual dysfunction
- Pain on ejaculation
- Erectile dysfunction
- Premature ejaculation
What are the investigations for chronic prostatitis?
- Urine dipstick and MSU
- Expressed prostatic secretions
- Consider Semen MCS
- STI screen(including blood borne viruses)
- Consider PSA(may be elevated in prostatitis or malignancy)
- Consider need for urological investigation to identify potential underlying structural abnormalities.
What is the management for chronic prostatitis/chronic pelvic pain syndrome?
- Analgesia
- Paracetamol
- NSAIDs with PPI cover
- Stool softeners
- Referral to pain team specialist may be needed, particularly if neuropathic pain is considered.
- Alpha-blockers (e.g. Tamsulosin) may be trialled if significant LUTS are present.
- Referral to urology if symptoms are severe or persistent, or diagnosis is uncertain
What is the management for chronic bacterial prostatitis?
- Referral to urology
- Antibiotic course may be given dependent on the suspected organism.
- Length of antibiotics courses vary, discussion with microbiology can help guide management.
- Analgesia
- Stool softeners
- Surgical intervention may be indicated e.g. transurethral resection of the prostate (TURP)
Define benign prostate hyperplasia?
Increase in the size of the prostate without malignancy. This causes bladder outlet obstruction and lower urinary tract symptoms.
What are the risk factors for benign prostate hyperplasia?
- Increasing age:particularly >50 years old
- Family history
- Ethnicity:more common in Afro-Caribbean men; black > white > Asian
- Diabetes
- Obesity:due to increased circulating oestrogens
What are the signs of benign prostate hyperplasia?
- Digital rectal examination
- Lower abdominal tenderness and palpable bladder
- Indicates acute urinary retention
- Perform bladder scan
- Requires urgent catheterisation
What are the symptoms of benign prostate hyperplasia?
- Lower urinary tract symptoms (LUTS)
- Voiding: hesitancy, weak stream, straining and dysuria, incomplete emptying, terminal dribbling
- Storage: urgency, frequency, nocturia (due to feeling of incomplete emptying), urgency incontinence
- Oliguria: if complete obstruction
- Lower abdominal pain and inability to urinate
What are the primary investigations for benign prostate hyperplasia?
- Urinalysis
- Prostate-specific antigen (PSA)
- U&Es
- International Prostate Symptom Score (I-PSS)
What is PSA?
Prostate-specific antigen (PSA):predicts prostate volume, progression and may suggest cancer if significantly raised; BPH can also raise PSA
What is I-PSS?
International Prostate Symptom Score (I-PSS):a 7-symptom questionnaire with an additional bother score to predict progression and outcome of benign prostate hyperplasia.
What are some complications of benign prostate hyperplasia?
- Acute urinary retention
- Urinary tract infections
- Renal dysfunction: due to obstructive uropathy
- Haematuria
- Bladder stones:secondary to urinary stasis
- Retrograde ejaculation
- Erectile dysfunction
- Strictures
- Incontinence
- TURP syndrome:
What is the management for a patient with benign prostate hyperplasia with non-bothersome symptoms?
- Reassurance and watchful waiting
- Conservative management: reduce caffeine and fluid intake, healthy diet regimens, exercise, medication review, bladder retraining
- In certain circumstances a long-term catheter, with changes every 3 months, may be used.
What is the management for a patient with benign prostate hyperplasia with bothersome symptoms (not surgical)?
- α-1 antagonists e.g. Tamsulosin. Considered first-line forsymptomatic relief
- 5-α reductase inhibitors e.g. finasteride
- Combination therapy: second-line management is a combination of the above