Reproductive Emergencies Flashcards

(30 cards)

1
Q

What can cause stump pyometra?

A

incomplete ovariectomy

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2
Q

When is hemorrhagic vaginal discharge normal in the bitch?

A

during proestrus phase

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3
Q

What are the 4 phases of the repro cycle in the dog?

A
  • proestrus
  • estrus
  • diestrus
  • anestrus
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4
Q

List 3 differentials for purulent vaginal discharge

A

metritis - usually postpartum animal
vaginitis
pyometra

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5
Q

When does pyometra occur?

A

Diestrus - when progesterone levels are high
typically within 1-4 months after estrus

preceded by cystic endometrial hyperplasia

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6
Q

What are the most common bacteria causing mastitis?

A

E. coli
Staph
Strep

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7
Q

What kind of uterus do bitches and queens have?

A

bicornuate uterus

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8
Q

Explain the initiation of parturition

A

initiated by fetuses

fetal adrenal gland maturation -> release cortisol
-> causes increased estrogen secretion by ovaries (45-60 days)
-> estrogen promotes prostaglandin E2 secretion
-> PGE2 is luteolytic -> corpus luteum regression
-> reduction in circulating progesterone
-> falling progesterone -> increase prolactin -> lactation
-> parturition within 24-48 hours of rapid progesterone decline
-> pressure on cervix -> oxytocin secretion -> myometrial contractility

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9
Q

Where is oxytocin secreted?

A

posterior pituitary

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10
Q

What are the stages of parturition and their duration?

A

stage 1
- 6-12 hours
- nesting, subclinical contractions

stage 2
- 2-12 hours (up to 24 hours in queens)
- overt contractions
- fetal expulsion

stage 3
- variable time
- placental expulsion
- uterine involution

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11
Q

What is the normal fetal heart rate?

A

200-220

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12
Q

List 5 indications for intervention in dystocia.

A
  • obstruction (apparent on xrays, US, or vaginal exam)
  • Fetal distress (HR <160-180)
  • Dam is systemically ill
  • uterine rupture or torsion suspected
  • Dam has not entered labor and progesterone is < 2 ng/mL
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13
Q

What should be administered together with oxytocin?

A

Ca-gluconate

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14
Q

What are prerequisites for medical management for dystocia (i.e., oxytocin) ?

A
  • labor has not been prolonged
  • no obstruction
  • fetusus deemed not too big for vaginal canl
  • cervix is dilated
  • electrolyte and acid-base abnormalities resolved/corrected
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15
Q

Describe how to perform a cesarian section

A
  1. ventral midline approach - incision from slightly cranial to umbilicus to just cranial to pubic bone
  2. visualize linea alba - lift linea alba before incising!
  3. identify uterus
  4. lift uterine horns and exteriorize them from the abdomen - laid on soaked/moistened laparotomy sponges
  5. make a small single uterine incision over the base with scalpel
  6. extend uterine incision with Metzenbaum scissors - extend just large enough to allow passage of fetus
  7. manipulate each fetus towards the same opening
  8. break the chorioallantois bluntly with hemostats to allow delivery of neonate from uterus
  9. rupture amnion and clamp and tie the umbilicus
  10. close uterus with inverting single layer (e.g., Cushings or Lemberts) - absorbable (e.g., 2-0 or 3-0 PDS or Monocryl)
  11. Administer SQ dose oxytocin AFTER uterus closure
  12. lavage abdomen
  13. close abdominal wall - make sure closing layer (external rectus fascia) is included in all bites (simple continuous or simple interrutped, PDS, 0 large dog, 2-0 otherwise)
  14. close subcutaneous space (Monocryl 2-0 or 3-0, simple continuous)
  15. skin closure (either simple interrupted or intradermal - puppies will nurse and higher risk of dehiscence if continuous with extern suture parts (Monocryl or PDS, 2-0 or 3-0)
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16
Q

What is the expected weight gain of neonatal puppies?

A

2-3 g per day per kg of expected adult weight

exception first 24 hours: may decrease slightly

17
Q

What is the most common time for eclampsia to develop?

A

2-4 weeks post-partum (peak lactation time)

18
Q

How does excessive prenatal Ca supplementation increase risk of eclampsia?

A

inhibits parathyroid hormone release and can promote parathyroid gland atrophy

stimulates thyroid calcitonin secretion

19
Q

How does hypocalcemia cause muscle contractions?

A

increases nerve cell permeability to sodium ions&raquo_space; excitatory effect&raquo_space; spontaneous discharge of nerve fibers&raquo_space; muscle contractions

20
Q

why should Ca-chloride be avoided to treat eclampsia?

A

very corrosive perivascular effect if extravasated

21
Q

What changes on the ECG indicate a too fast Calcium infusion?

A
  • bradycardia
  • QT shortening
  • arrhythmias
22
Q

How should the offsprings of a dam with eclampsia be managed (weaning etc.)?

A
  • hand-feed with milk supplement for 24-36 weeks before reintroducing
  • if > 4 weeks&raquo_space; wean puppies
23
Q

If persistent hypocalcemia/eclampsia is expected, how can this be treated?

A

Calcitriol administration - monitor iCa to identify iatrogenic hypercalcemia early

24
Q

What medication can be given to help stop lactation after eclampsia episode?

A

Cabergoline (antiprolactinic drug)

25
What type of virulence factor is often seen in E.coli strains causing pyometra and what does this enhance?
Uropathogenic virulence factor (UVF) enhances endometrial adherence
26
What are the most common chemistry abnormalities in dogs with pyometra?
* azotemia * increased liver enzymes * elevated tbili * hypercholesterolemia * hyperglobulinemia * hypoalbuminemia * hyperproteinemia
27
What is the recommended antibiotic therapy for pyometra?
fluoroquinolone + extended-spectrum penicillin e.g., unasyn + enro other appropriate choices: * TMS * 3rd gen cephalosporin
28
What is the recommendation on antibiotic therapy post surgery for pyometra?
2 weeks
29
What are the treatment options for medical management of pyometra?
* PGF2-alpha * dopamine agonists * progesterone receptor antagonist (antiprogestins) either alone or in combination, GOAL: open cervix for purulent discharge to be expelled + antibiotic coverage + allow endometrial regeneration by prolonging anestrus period (androgen receptor agonists, mibolerone)
30
If medical management for pyometra is pursued, what is the recommendation for future breeding?
pregnancy is protective against pyometra recommended to breed the next cycle