Reproductive Health Flashcards

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1
Q

PTEN Gene (phosphate and tension homolog) is inactivated in what disease. What does this predispose one too?

A

Cowden’s Disease ( multiple hamartoma syndrome) and it can cause endometrial hyperplasia and Ca.

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2
Q

What imaging is best for epididymitis?

A

U/S

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3
Q

What is the treatment of Endometriosis?

A

Combined BC pills

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4
Q

What non oral modification should be considered in children with cleft palate?

A

Ear tubes due to the risk of otitis media

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5
Q

Drug that can cause adenocarcinoma of the vagina with in utero exposure?

A

Diethylstilbestrol

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6
Q

What complication might a Linguine sign suggest?

A

Ruptured breast implant

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7
Q

What are physiological risks of Breast ca. (4)

A

Female, nulliparis, early menarche, late menopause

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8
Q

Adenocarcinoma of the nipple

A

Paget’s Disease

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9
Q

Solid lesions in the duct that present with clear or bloody nipple discharge

A

Intra-ductal papillomas

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10
Q

Treatment for ______ could possibly cause self limiting hypotonia in an infant?

A

Pre-eclampsia.

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11
Q

3 cancers that commonly metastasize to the leptomeninges of the brain

A

Breast, Lung, Melanoma

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12
Q

TRX for ectopic pregnancy

A

methotrexate

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13
Q

Septic abortion trx??

A

IV ABx + cervical dilation and curettage

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14
Q

Pregnancy what happens hormonally?

A

Syncytiotrophoblast produces human chorionic gonadotropin (hCG), which stimulates progesterone production by the corpus luteum.

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15
Q

Mullerian agenesis

A

Failure to develop upper vagina and uterus. Blind pouch

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16
Q

Dx for Hirschsprung retention

A

rectal biopsy showing lack of ganglionic cells

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17
Q

What infection can increase risks of ectopic pregnancy

A

chlamydia or any Pelvic inflammatory disease that damages fallopian tubes.

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18
Q

first line treatment for nonclassical adrenal hyperplasia

A

glucocorticoids

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19
Q

vaginismus and trx:

A

pain with penetration, due to pelvic floor spasm. Desensitization theory

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20
Q

Aplasia cutis congenita?

A

congenital focal absence of skin. Assoc with trisomy 13

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21
Q

btw what layers does an epidermal go

A

Ligmentum Flavum and Dura mater

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22
Q

Breastfeeding vs Breastmilk jaundice?

A

3-5 day onset compared to 1-6weeks

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23
Q

when to screen for gestational DM?

A

late 2nd trimester (24-28wks)

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24
Q

imperforate hymen in a newborn description?

A

Imperforate hymen presents in neonates as a bulging blue domed, translucent membrane at the level of the vaginal introitus

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25
placental abruption symptoms and risks?
Acutely Painful abdomen. Bleeding. low amplitude but rapid contractions. risks: Trauma, cocaine
26
Staghorn calculi composition and associations?
struvite. Appears as calcifications surrounding the kidney after Proteus, Klebsiella, Pseudomonas, and Enterobacter UTI's
27
Trichomoniasis infection in women symp?
vaginal and vulvar erythema, vaginal burning and pruritus, and foul, thin, yellow-green discharge. sometimes strawberry cervix.
28
Lichen plantus vs lichen sclerosis
Plantus in the vagina sclerosis in general vulvula region
29
at what time is penicillin given to a . GBS positive woman?
onset of labor
30
imperforate hymen diagnosis?
U/S
31
caudal regression syndrome is associated with what maternal risk factor?
Diabetes
32
class of medications given to delay labor?
beta 2 agonists
33
Asherman syndrome
Scarred uterus from gynecological surgeries leading to possible secondary amenorrhea
34
What drugs are given to help pass a inevitable abortion
misoprostol and oxytocin
35
Lynch syndrome and associated cancers
Hereditary nonpolyposis colorectal cancer | ASSOC with: colon, ovarian, endometrial, and breast cancers
36
common palsy from shoulder dystocia
Erb Duchenne palsy C5 and C6 nerve roots
37
What tumor marker to track progress of cancer trx on ovarian dysgerminoma?
LDH
38
What tumor marker to track progress of cancer trx on ovarian epithelial tumor?
Ca-125
39
Treating Gonorrhea and chlamydia
Gonorrhea- ceftriaxone Chlamydia= doxycycline or azithromycin
40
Squamous cell carcinoma in an area where semen goes is caused by what infection??
HPV
41
Tubo ovarian abscess trx?
Occurs after PID. IV Cefoxitin and PO or IV doxycycline and if no improvement in 48hrs drain the abscess
42
Drug for woman trying to conceive with PCOS
clomiphene.
43
Blind Pouch, no tubes or uterus, normal hormones 46XX
Mullerian agenesis
44
asymmetrical uterus and chronic pain + bleeding classis for
fibroids
45
Hot flashes trx
venlafaxine
46
Postpartum blood loss
500cc for vaginal or 1000cc for C-section
47
Bethanechol vs Oxybutynin
Oxybutynin for spastic bladder | Bethanechol for flacid
48
Bladder cancer diagnosis
cystoscopy
49
hyperemesis gravidarum what you do
Correct electrolyte abnormalities and screen for moles with Beta HCG then do U/S to double check
50
vaginismus trx
kegels and dilators to relax pelvic floor
51
danger of pregnancy over 41 wks?
oligohydramnios
52
epigastric pain in pregnancy think...
Gerd of Capsular stretch from eclampsia
53
During labor uterus becomes boggy and soft? What do | you do?
Crash C section
54
Best initial test for fetal anemia
middle cerebral artery doppler
55
hx of fetal loss during 2nd trimester increases risk for what?
cervical insufficiency
56
Hypothyroidism during pregnancy counseling
Levothyroxine dose will need to increase (as estrogen increases so does Thyroid binding globulin effectively decreasing active dose.)
57
Ferning on the slide and thin stringy vaginal mucus. What stage of Menstrual cycle
Ovulation
58
What do you do if baby needs more time and no ROM?
Tocolytics+ steroids
59
tachysystole?
5+ contractions every 10 min
60
tachysystole trx
terbutaline 1st line tocolytic (beta 2 agonist) side effect is pulmonary edema
61
adequate accelerations
15 up in 15 seconds and 2 in 20 min
62
Prom?
18 hours since water broken. treat with amp and gent
63
Clomiphene?
induces ovulation
64
Kleihauer Berke test
used to look for compatibility issues and dose rhogam
65
Proteinuria
Pr/Cr greater than 0.3 or 300mg/day
66
School of fish on histology
chancroid
67
Derm manifestations of pregnancy
1. Intrahepatic cholestasis- Itching at night palms and soles 2. pruritic urticarial plaques and papules 3. Herpes stations
68
Acute fatty liver of P
n/ v, LFT's, caused by mitochondria dysfunction
69
Magnesium toxicity sign
hyporeflexia
70
prematurity supplements
<32wks: Mg, tocolytics, steroids 32-34: tocolytics + steroids 34-37: steroids
71
Vaginal delivery for HIV mom
viral load under 1000/ml
72
ureteral diverticulum vs vesicovaginal connection
diverticulum is intermittent leaking while a connection is constant
73
Short cervix no history of preterm?
projesterone to prevent rupture
74
Contraindicated med in Myasthenia Gravis
Magnesium
75
treatment for lichen sclerosis
clobetasol
76
Lichen Planus
50-60y/o | Itchy. May be either erosive with white borders or papulosquamous with a purple hue
77
Pre eclampsia and crackles
pulmonary edema due to vasospasm causing high resistance of peripheral vessels so fluid backs up in the lungs
78
ovulation induction treatments, ascites, distention and bilateral enlarged ovaries?
Ovarian hyperstimulation syndrome
79
Diethylstilbestrol in utero exposure?
clear cell vaginal adenocarcinoma
80
Tamoxifen adverse effects
VTE Increased endometrial cancer risk Hot flashes
81
postmenopausal bleeding =
bx or u/s
82
Pylo in pregnancy treatment
IV abx
83
Preeclampsia feared complication
CVA
84
Methyergonovine contra indication
HTN disorders due to vasoconstrictor
85
Amino infusion use
Variable decelerations to take pressure off umbilical cord
86
In rapid virilization what does high T and normal DHEAS tell you
Some type of ovarian source likely sertoli leydig tumor
87
Treatment for high risk of pre eclampsia ?
Asa at 16 weeks until delivery