Reproductive Physiology I Flashcards

(59 cards)

1
Q

Male and female gametes have __(#) chromosomes

A

23

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2
Q

What process occurs between male and female gametes to form an egg ?

A

Fertilization

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3
Q

Fertilization of male and female gametes cells fuse to form a fertilized ____

A

Egg

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4
Q

After fertilization of male and female gametes, the fertilized egg now have ___(#) chromosomes

A

46

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5
Q

The ___ are reproductive organs that generate gametes

A

Gonads

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6
Q

Gonads are primary reproductive organs that generate ____

A

Gametes

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7
Q

Determination of genetic sex of an embryo is dictated by which chromosomes the ___ delivers

A

Sperm

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8
Q

Embryonic window for sex specification starts at ___ weeks of gestation

A

6

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9
Q

Ovum with X sex chromosome Is fertilized by sperm with ___ sex chromosome to yield an embryo with ___ sex chromosomes = male

A

Y
XY

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10
Q

Ovum with X sex chromosome Is fertilized by sperm with ___ sex chromosome to yield an embryo with ___ sex chromosomes = FEMALE

A

X
XX

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11
Q

From conception to week 6 of embryonic development a male or female embryo is internally and externally _______in terms of reproductive system

A

Identical

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12
Q

Müllerian duct refers to the female or male reproductive tract ?

A

Female

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13
Q

Wilffian duct refers to the female or male reproductive tract ?

A

Male

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14
Q

___ duct refers to the female reproductive tract

A

Mullerian

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15
Q

__ duct refers to the male reproductive tract

A

Wolffian

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16
Q

Starting at what week of embryonic development can we determine the sex of an embryo ?

A

7

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17
Q

The SRY transcription factor is the sex-determining gene of the ___ chromosome

A

Y

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18
Q

___ sex depends on combination of sex chromosomes

A

Genetic

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19
Q

____ sex is determined by presence or absence of SRY gene

A

Gonadal

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20
Q

What is the sex if SRY and TDF are absent

A

Female

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21
Q

With no TDF , undifferentiated gonads develop into ____

A

Ovaries

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22
Q

TDF directs differentiation of gonads into ___

A

Testes

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23
Q

TDF is short for ____

A

Testes determining factor

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24
Q

Are reproductive tracts differentiated before or after gonads ?

25
_____+ ____ from the testes signal wolffian duct development in the male embryo
Androgens + MIF
26
Androgens + MIF from testes signal ___ duct development in the male embryo
Wolffian
27
Androgens +MIF from tests signal wolffian duct development in the ____ embryo
Male
28
Absence of androgens + MIF permits Müllerian duct development in ___ embryo
Female
29
Absence of androgens + MIF permits_____ duct development in female embryo
Müllerian
30
Absence of _____ + ____ permit Müllerian duct development in the female embryo
Androgens + MIF
31
Testes secret ____ and _____
Testosterone and mullerian -inhibiting factor
32
Degeneration of Müllerian ducts is done by means of ________
Mullerian inhibiting factor
33
Testes secrete testosterone which is converted to _____
Dihydrotestosterone
34
_______ promotes development of undifferentiated external genitalia along male lines
Dihydrotestosterone
35
Testosterone, MIF and dihydrotestosterone are ____ steroids
Androgenic
36
MIF= a ___ hormone
Protein
37
MIF stands for
Mullerian inhibiting factor
38
____ sex determined by presence or absence of masculinizing hormones
Phenotypic
39
Absence of testosterone promotes the degeneration of ___ ducts
Wolffian
40
Absence of MIF promotes development of _____ ducts into female reproductive tract
Mullerian
41
Absence of_____ promotes development of undifferentiated external genitalia along female lines
testosterone
42
Gonadal sex specification of embryo can be determined at ___-___ weeks
6-7
43
Sex specific hormones profiles of embryo can be determined at __-___ weeks
7-9 weeks
44
Genetic sex of embryo can be determined at what stage of development ?
Conception
45
Phenotypic sex (differentiation of external genitalia) of embryo can be determined at __-___ weeks
10 -12
46
______ is essential for development of male external genitalia
Dihydrotestosterone
47
Ovaries remain in the abdominal cavity Testes descend into the scrotum under the influence of _____
Androgens
48
______ % of male newborns have descended testes, remainder within 3 months post birth
97%
49
Absent ___ or ___ signalling in a male embryo leads to female development
SRY or TDF
50
Absent SRY or TDF signalling in a Male embryo results in _______
Female development
51
Absent ___ in a male embryo = male testes and female physical appearance with breast development
Androgen receptor
52
Absent androgen receptor in a male embryo = male testes and ___ physical appearance with ______ development
Female Breast
53
Insufficient _____ to DHT conversion in a male embryo = male testes and reproductive tract ; female external genitalia
Testosterone
54
Insufficient testosterone to ____ conversion in a male embryo = male testes and reproductive tract ; female external genitalia
DHT
55
Insufficient testosterone to DHT conversion in a male embryo = male testes and reproductive tract ; ______external genitalia
Female
56
Excessive ___ production in a female embryo = female ovary; male - differentiation of the reproductive tract and genitalia
Androgen
57
Excessive androgen production in a female embryo = female ______; male - differentiation of the reproductive tract and _____
Ovary Genitalia
58
DSD stands for
Difference in sexual differentiation
59
Explain the difference between genetic sex, gonadal sex and phenotypic sex
Genetic- inheritance of Chr XX or Chr XY combination Gonadal - presence/absence of SRY gene Phenotypic - presence/absence of masculinizing hormones