Reproductive System Flashcards
(49 cards)
Acrosin
Enzyme that activates the sperm
Neuraminidase and Hyaluronidase
Enzymes that help sperm penetrate the corona radiata and zona pellucida of ovum
Where are sperm produced?
Sperm are produced by germ cells in the seminiferous tubules
What 2 functions do the Interstitial Cells of Leydig have?
- Secrete testosterone used to develop secondary sex characteristics
- Work with FSH to stimulate sperm
Sertoli Cells
Support cells joined tightly together to form the blood-testis barrier
How does the blood-testis barrier protect sperm from the immune system?
It prevents an immune response towards the surface antigens on sperm
Anti-Mullerian Hormone (AMH)
-Secreted by Sertoli cells during the early stages of fetal life
Result: The male reproductive duct develops; thus if mullerian duct developed, the women’s reproductive duct would develop
Inhibins and Activins
- Secreted by Sertoli cells after puberty
- They work together tp regulate FSH secretion
Androgen Binding Protein
- AKA Testerone binding globulin
- Increases testosterone concentration in the seminiferous tubules to stimulate spermatogenesis
Estradiol
Aromatase from Sertoli cells convert testosterone to 17 beta estradiol to DIRECT spermatogenesis
Glial cell line-derived neurotrophic factor (GDNF)
- Secreted by Sertoli cells
- Functions in promoting undifferentiating spermatogonia, which ensures stem cell self-renewal during the perinatal (after birth) period
ETS Related Molecule
- Secreted by Sertoli cells
- AKA ERM transcription factor
- Needed for maintenance of the spermatogonial stem cell in the adult testis
Transferrin
- Secreted by Sertoli cells
- A blood plasma protein for iron ion delivery
Travel of Sperm
Leave the Seminiferous Tubules via efferent ducts-> epididymis to mature for 2 weeks consuming fructose-> vas deferens
The Dartos Muscle
- Lines the scrotum
- Responsible for contraction of the scrotum when cold and relaxation when hot; also forms a septum in the scrotum
Vasectomy
Tying and cutting the vas deferens for contraceptive purposes; ONLY SPERM AND FRUCTOSE are being cut off (not the 3 glands)
Vasovasostomy
Reversal of a vasectomy
The Cremaster Muscle
- Within the scrotum
- AKA the ductus deferens or the spermatic duct
- It leaves the epididymis carrying sperm and fructose during ejaculation
What is semen made of?
Sperm, secretions from the seminal vesicle, prostate, and cowper’s/bulbourethral gland
Seminal Vesicle Secretions
An alkaline, viscous fluid high in fructose, prostaglandins, and fibrinogen
What does fibrinogen do?
It coagulates and thus thickens the semen
Prostate Secretions
A milky secretion containing citric acid (used by sperm make ATP), enzymes that work with fibrinogen to coagulate semen and seminal plasmin
*Makes the semen white
Seminal plasmin
Antibiotic that destroys certain bacteria; Keeps the bacteria in the vagina under control to protect the entering sperm and ensure fertilization
Cowper’s/ Bulbourethral Gland
An alkaline liquid used to lubricate the urethra for smooth passage of semen and to neutralize vaginal and residual urethral acidity