Reproductive System (Male Histo) Flashcards

(29 cards)

1
Q

State the type of cells in scrotal skin.
What type of glands can be found in scrotal skin?

A

SCROTAL SKIN - KSSE (keratinised simple squamous epithelium)
- Sebaceous glands
- Apocrine glands

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2
Q

SCROTUM
- Outpouching of lower part of ____ abdominal wall
- ____ cutaneous sac in perineum contains ____, ____ and ____
- 2 muscles in the scrotum =

A

SCROTUM
- Outpouching of lower part of ANTERIOR abdominal wall
- FIBROMUSCULAR cutaneous sac in perineum contains EPIDIDYMIS, TESTIS and SPERMATIC CORD
- 2 muscles in the scrotum = DARTOS MUSCLE + CREMASTER MUSCLE

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3
Q

State the homologous structures of the scrotal muscles in the anterior abdomianl wall.
State the innervation of the muscles.

A

DARTOS MUSCLE - continuation of CAMPER’S FASCIA (sheet of smooth muscle)
- innervated by sympathetic fibres from genital branch of genitofemoral nerve (L1-L2)

CREMASTER MUSCLE - continuation of IOM (sheet of skeletal muscle)
- innervated by genital branch of genitofemoral nerve (L1-L2) and branch of lumbar plexus

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4
Q

CREMASTERIC RELFEX
- ____ reflex elicited by gentle stroking of inner thigh
- Afferent = sensory input of reflex mediated by ____ nerve and ____ branch of ____ nerve which innervate skin of upper thigh and groin
- Efferent = motor response mediated by ____ branch of ____ nerve which innervates cremaster muscles
- Spinal cord = reflex arc involves spinal cord segments ____ - ____ where motor signals stimulate cremaster muscle –> contraction and ____ of testis

A

CREMASTERIC RELFEX
- SUPERFICIAL reflex elicited by gentle stroking of inner thigh
- Afferent = sensory input of reflex mediated by ILIOINGUINAL nerve and FEMORAL branch of GENITOFEMORAL nerve which innervate skin of upper thigh and groin
- Efferent = motor response mediated by GENITAL branch of GENITOFEMORAL nerve which innervates cremaster muscles
- Spinal cord = reflex arc involves spinal cord segments L1 - L2 where motor signals stimulate cremaster muscle –> contraction and ELEVATION of testis

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5
Q

Explain how the 2 scrotal muscles act to maintain scrotal temperature

A
  1. when scrotum is exposed to cold temperature –> dartos and cremaster muscles contract to bring testes closer to body –> reduce SA of scrotal skin exposed to cold environment
  2. when scrotum exposed to hot temperatures, dartos and cremaster muscles relax to allow testes to hang further from body –> increase distance from body’s core heat –> increase SA of scrotal skin to facilitate heat dissipation
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6
Q

State the homologous structure of scrotum in females.

A

labia majora

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7
Q

State the lymph nodes to be palpated during infections of the scrotal area.

A

superficial inguinal nodes

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8
Q

Label the testes

A
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9
Q

TESTES
- Average size:
- Oval shape
- Homologous to ____ in females
- One testis is bogger than the other
- ____ testis usually hangs lower
- Function:

A

TESTES
- Average size: 4-5cm
- Oval shape
- Homologous to OVARIES in females
- One testis is bigger than the other
- LEFT testis usually hangs lower
- Function: Seminiferous tubules produce in sperm and collect in rete testis + Contains endocrine cells (leydig) to produce testosterone

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10
Q

State the blood supply and blood drainage of TESTES

A

BLOOD SUPPLY - testicular A <– abdominal A

BLOOD DRAINAGE
- Left testis = Left renal vein –> IVC
- Right testis = IVC directly
- Venous drainage is achieved by paired testicular veins forming pampiniform plexus in scrotum –> network of veins wrapped around testicular A

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11
Q

State the nodes that testes drain into

A

para-aortic nodes (palpate during testicular cancer)

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12
Q

TUNICA ALBUGINEA - dense ____ tissue covering the testis
- Consists of ____, ____ and few ____ muscle cells
- Tunica ____ = inner part containing ____ tissue with ____ and blood vessels

A

TUNICA ALBUGINEA - dense CONNECTIVE tissue covering the testis
- Consists of FIBROBLASTS, MYOFIBROBLASTS and few SMOOTH muscle cells
- Tunica VASCULOSA = inner part containing CONNECTIVE tissue with LYMPHATICS and blood vessels

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13
Q

LEYDIG CELLS
- Cells located in ____ supporting tissues between the seminiferous tubules
- Occurs singly or in ____ embedded in rich plexus of blood and lymph capillaries
- Abundant ____ as it is site for steroid hormone synthesis
- Functions =

A

LEYDIG CELLS
- Cells located in INTERSTITIAL supporting tissues between the seminiferous tubules
- Occurs singly or in CLUMPS embedded in rich plexus of blood and lymph capillaries
- Abundant SER as it is site for steroid hormone synthesis
- Functions = Testosterone synthesis + Hormonal regulation (produce testosterone in presence of LH)

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14
Q

SEMINIFEROUS TUBULES
- Structure where ____ occurs
- Formation of ____ occurs only during reproductive period which begins at puberty ( ____ - ____ years old)
- Sertoli cells = ____ cells with extensive ____ and ____ processes that surround the adjacent spermatogenic cells
- Functions of sertoli cells =

A

SEMINIFEROUS TUBULES
- Structure where SPERMATOGENESIS occurs
- Formation of SPERMATOZOA occurs only during reproductive period which begins at puberty ( 12 - 16 years old)
- Sertoli cells = COLUMNAR cells with extensive APICAL and LATERAL processes that surround the adjacent spermatogenic cells
- Functions of sertoli cells = Provides BTB (blood-testis barrier) to prevent toxins from entering the seminiferous tubules + Secretes inhibin B, ABP and anti-mullerian hormone + Phagocytic functions to clean up cellular debris

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15
Q

SPERMATIC CORD
- Arises at ____
- Passes through ____ canal
- Exits at superficial ____ ring into ____ before terminating at ____ border of testes

A

SPERMATIC CORD
- Arises at DEEP INGUINAL RING
- Passes through INGUINAL canal
- Exits at superficial INGUINAL ring into SCROTUM before terminating at POSTEROMEDIAL border of testes

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16
Q

VAS DEFERENS
- Long, thick-walled muscular tube with relatively ____ lumen that transports sperm cells from ____
- Leaves the ____ and continues towards the ____ urethra where it empties
- Function =

A

VAS DEFERENS
- Long, thick-walled muscular tube with relatively SMALL lumen that transports sperm cells from EPIDIDYMIS
- Leaves the SCROTUM and continues towards the PROSTATIC urethra where it empties
- Function = Produces strong peristaltic contraction to expel spermatozoa into prostatic urethra within a very short period during ejaculation

17
Q

State what occurs in a vasectomy.

A

Vasectomy = incision is made in the scrotum and vas deferens on either side is cut and tied for male sterilisation

18
Q

State the epithelium cell type in vas deferens.

A

pseudostratified columnar epithelium

19
Q

VAS DEFERENS
- Epithelial lining and lamina propria are thrown into multiple folds to allow for ____
- Tall ____ cells have few ____
- Inner and outer ____ layer
- Thick middle ____ layer

A

VAS DEFERENS
- Epithelial lining and lamina propria are thrown into multiple folds to allow for EXPANSION
- Tall COLUMNAR cells have few STEREOCILIA
- Inner and outer LONGITUDINAL layer
- Thick middle CIRCULAR layer

20
Q

State the contents of the spermatic cord (5)

A
  1. vas deferens
  2. testicular A
  3. pampiniform plexus of veins
  4. genital branch of the genitofemoral N
  5. lymphatics and sympathetic and parasympathetic nerve fibres
21
Q

EPIDIDYMIS
- Long ____ tube that transports sperm from ____ to ____
- Tightly coiled
- Lies in ____ along ____ and ____ side of each testis
- Functions =

A

EPIDIDYMIS
- Long COILED tube that transports sperm from TESTES to VAS DEFERENS
- Tightly coiled
- Lies in SCROTUM along POSTEROLATERAL and SUPERIOR side of each testis
- Functions = Head receives spermatozoa from testis via efferent ductules + Body facilitates functional maturation of spermatozoa to develop motility + Tail for storage of sperm until ejaculation

22
Q

EPIDIDYMIS
- Duct of epididymis is lined by ____ epithelium
- 3 types of cells =

A

EPIDIDYMIS
- Duct of epididymis is lined by PSEUDOSTRATIFIED COLUMNAR epithelium
- 3 types of cells = Principal cell + Basal cell + Smooth muscle layer

23
Q

EPIDIDYMIS
- Principal cell = tall ____ with long ____ that project into lumen to facilitate ____ and ____
- Basal cell = small, ____ cells near the basement membrane responsible for producing new cells
- Smooth muscular layer = increases from a single layer at the proximal end to ____ layers at the distal end

A

EPIDIDYMIS
- Principal cell = tall COLUMNAR with long STEROCILIA that project into lumen to facilitate ABSORPTION and EXCRETION
- Basal cell = small, ROUND cells near the basement membrane responsible for producing new cells
- Smooth muscular layer = increases from a single layer at the proximal end to 3 layers at the distal end

24
Q

SEMINAL VESICLES
- Pair of highly ____ positioned below the posterior wall of urinary bladder
- Contributes ____ - ____ % of seminal fluid containing ____, ____, ____ and ____

A

SEMINAL VESICLES
- Pair of highly COILED positioned below the posterior wall of urinary bladder
- Contributes 70 - 80 % of seminal fluid containing PROTEIN, MUCOUS, FRUCTOSE and PROSTAGLANDINS

25
State the type of cells that line the SEMINAL VESICLES
seminal vesicles - pseudostratified columnar epithelium
26
**PROSTATE GLAND** - Produces prostatic fluid that makes up around ____ % of seminal fluid - Located directly ____ to neck of urinary bladder - Serum marker for prostatic cancer =
**PROSTATE GLAND** - Produces prostatic fluid that makes up around **30** % of seminal fluid - Located directly **POSTERIOR** to neck of urinary bladder - Serum marker for prostatic cancer = **PSA**
27
**PROSTATE GLAND** - Composed of ____ glands and stroma - Prostatic stroma is ____ with abundant ____ muscle cells mixed with ____, blood vessels and nerves - Glands are lined by ____ epithelium - Corpora ____ = concretions of prostatic fluid in lumen of some glands (especially seen in ____ men) + contains ____ and keratin sulfate + has concentric ____ appearance - No ____ tisue is present in prostate - Basal cells = small, round stem cells resting on basement membrane
**PROSTATE GLAND** - Composed of **TUBULOALVEOLAR/TUBOLOACINI** glands and stroma - Prostatic stroma is **FIBROMUSCULAR** with abundant **SMOOTH** muscle cells mixed with **FIRBOBLASTS**, blood vessels and nerves - Glands are lined by **PSEUDOSTRATIFIED COLUMNAR** epithelium - Corpora **AMYLACEA** = concretions of prostatic fluid in lumen of some glands (especially seen in **OLDER** men) + contains **GLYCOPROTEIN** and keratin sulfate + has concentric **LAMELLAR** appearance - No **ADIPOSE** tisue is present in prostate - Basal cells = small, round stem cells resting on basement membrane
28
**PENIS** (1) ***Corpus cavernosa*** = surrounding by tough fibrous sheath called ____ - Composed of numerous blood-filled spaces (____) lined by enthelial cells which fill with blood during erection when smooth muscle fibres relax and sinusoids dilate - Spaces separated by ____ containing ____ muscle fibres and connective tissue (2) ***Corpus spongiosum*** = surrounds the urethra - Contains ____ and ____ sinusoids compared to corpora cavernosa - Tissue is more ____ to prevent urethral compression during erection
**PENIS** (1) ***Corpus cavernosa*** = surrounding by tough fibrous sheath called **TUNICA ALBUGINEA** - Composed of numerous blood-filled spaces (**SINUSOIDS**) lined by enthelial cells which fill with blood during erection when smooth muscle fibres relax and sinusoids dilate - Spaces separated by **TRABECULAE** containing **SMOOTH** muscle fibres and connective tissue (2) ***Corpus spongiosum*** = surrounds the urethra - Contains **FEWER** and **SMALLER** sinusoids compared to corpora cavernosa - Tissue is more **ELASTIC** to prevent urethral compression during erection
29
State the types of epithelium in 1. pre-prostatic urethra 2. prostatic urethra 3. membranous urethra 4. spongy urethra
pre-prostatic urethra - **transitional epithelium** prostatic urethra - **transitional epithelium** membranous urethra - **pseudostratified columnar epithelium** spongy urethra - p**seudostratified columnar epihtelium** except for **terminal** protion whcih is by **stratified squamous epithelium**