Rescue Asthma Drugs in Asthma and COPD

Question 1

Drug Class: Albuterol HFA

Answer 1

Inhaled SABA

Question 2

Brand Name: Albuterol HFA

Answer 2

ProAir
Ventolin
Proventil
ProAir-Respiclick
ProAir Digihaler

Question 3

Dosage Form: Albuterol HFA

Answer 3

Metered Dose Inhaler (MDI)
Aerosol Powser Inhaler (Respiclick and Digihaler)

Question 4

Age Group Dosing: Albuterol HFA

Answer 4

all ages

Question 5

Drug Class: Albuterol

Answer 5

Inhaled SABA

Question 6

Brand Name: Albuterol

Answer 6

there isn’t one :(

Question 7

Dosage Form: Albuterol

Answer 7

Nebulizer Solution

Question 8

Age Group Dosing: Albuterol

Answer 8

all ages

Question 9

Adverse Effects: Albuterol

Answer 9

tachycardia
tremor
hypokalemia
irritability

Question 10

Clinical Pears: Albuterol

Answer 10

chronic use (>2x/day) indicates poor asthma control

may mix nebulizer solution with cromolyn solution, busesonide inhalent suspension, or ipratropium solution

in mild to moderate exacerbations, MDI plus valved holding chamber is as effective as nebulized therapy with appropriate administration technique and coaching by trained personally

Question 11

Drug Class: Levalbuterol HFA

Answer 11

Inhaled SABA

Question 12

Brand Name: Levalbuterol HFA

Answer 12

Xopenex

Question 13

Dosage Form: Levalbuterol HFA

Answer 13

MDI

Question 14

Age Group Dosing: Levalbuterol HFA

Answer 14

All Ages

Question 15

Drug Class: Levalbuterol

Answer 15

Inhaled SABA

Question 16

Brand Name: Levalbuterol

Answer 16

Xopenex

Question 17

Dosage Form: Levalbuterol

Answer 17

Nebulizer Solution

Question 18

Age Group Dosing: Levalbuterol

Answer 18

All Ages

Question 19

Adverse Effects: Levalbuterol

Answer 19

tachycardia
tremor
hypokalemia
irritability

Question 20

Clinical Pearls: Levalbuterol

Answer 20

reserved for patients who do not respond to albuterol for quick relief

nebulizer solution compatible with budesonide inhalent suspension

levalbuterol administration in 1/2 the mg dose of albuterol provides comparable efficacy and safety

has not been evaluated by continuous nebulization

Question 21

Drug Class: Ipratropium HFA

Answer 21

SAMA

Question 22

Brand Name: Ipratropium HFA

Answer 22

Atrovent

Question 23

Dosage Form: Ipratropium HFA

Answer 23

MDI

Question 24

Age Group Dosing: Ipratropium

Answer 24

all ages

Question 25

Dosage Form: Ipratropium

Answer 25

Nebulizer solution

Question 26

Age Group Dosing: Ipratropium

Answer 26

all ages

Question 27

Adverse Effects: Ipratropium

Answer 27

dry mouth urinary retention infection sinusitis bronchitis

Question 28

Clinical Pearls: Ipratropium

Answer 28

used in combo with albuterol for asthma exacerbation treatment may mix in same nebulizer with albuterol should not be used as first-line therapy; should be added to SABA therapy for severe exacerbations

Question 29

Drug Class: Ipratropium/Albuterol

Answer 29

SAMA

Question 30

Brand Name: Ipratropium/Albuterol

Answer 30

Combivent Respimat DuoNeb

Question 31

Dosage Form: Ipratropium/Albuterol

Answer 31

MDI (Respimat) Nebulizer Solution (DuoNeb)

Question 32

Age Group Dosing: Ipratropium/Albuterol

Answer 32

all ages

Question 33

Adverse Effects: Ipratropium/Albuterol

Answer 33

see individual products

Question 34

Clinical Pearls: Ipratropium/Albuterol

Answer 34

may be used for up to 3 hours in initial management of severe exacerbations (nebulizer)

Question 35

Drug Class: Methylprednisolone

Answer 35

Systemic Corticosteroids

Question 36

Dosage Form: Methylprednisolone

Answer 36

Tablets Oral Liquid

Question 37

Age Group Dosing: Methylprednisolone

Answer 37

all ages

Question 38

Drug Class: Prednisolone

Answer 38

Systemic Corticosteroids

Question 39

Dosage From: Predisolone

Answer 39

Tablets Oral Liquid

Question 40

Age Group Dosing: Prednisolone

Answer 40

All ages

Question 41

Drug Class: Prednisone

Answer 41

Systemic Corticosteroids

Question 42

Dosage Form: Prednisone

Answer 42

Tablets Oral Liquids

Question 43

Age Group Dosing: Prednisone

Answer 43

all ages

Question 44

Drug Class: Dexamethasone

Answer 44

Systemic Corticosteroids

Question 45

Dosage Form: Dexamethasone

Answer 45

Oral Liquid Tablets Injection

Question 46

Age Group Dosing: Dexamethasone

Answer 46

0-4 yo

Question 47

Drug Class: Methylprednisolone Acetate

Answer 47

Systemic Corticosteroids

Question 48

Dosage Form: Methylprednisolone Acetate

Answer 48

Repository Injection

Question 49

Age Group Dosing: Methylprednisolone Acetate

Answer 49

all ages

Question 50

Adverse Effects: Systemic Corticosteroids

Answer 50

hyperglycemia increased appetite fluid retention demargination of WBCs psychiatric disturbances

Question 51

Clinical Pearls: Systemic Corticosteroids

Answer 51

CI: systemic fungal infections, administration of live vaccine if immunocompromised DI: Warfarin INR increase, decreased efficacy of inactivated vaccines may be used with ICS if patient is already taking ICS before hospitalization may also be used for chronic therapy in both asthma and COPD only in severe stages bursts effective for establishing control when intiating therapy or during period of gradual deterioration injection may be used in place of burst if adherence is an issue or patient is vomiting

Question 52

Epinephrine Injection

Answer 52

no proven advantage of systemic therapy over aerosol indicated in addition to standard therapy for acute asthma associated with anaphylaxis and/or angioedema

Question 53

Terbutaline Injection

Answer 53

no proven advantage of systemic therapy over aerosol

Question 54

Magnesium sulfate IV

Answer 54

AE: flushing, hypotension, vasodilation CI: heart block, caution in renal dysfunction Consider if patient remains in life-threatening exacerbation after 1 hour of therapy