Respiratory Flashcards

(35 cards)

1
Q

What are some clinical features on exam for COPD?

A
  • Hyperinflated chest, reduced chest expansion
  • Increased resonance on percussion
  • Decreased breath sounds with end exp wheeze
  • Signs of RV failure in end stage
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2
Q

What Ix do you see in COPD?

A

FBE - Polycythaemia
ABG - hypoxaemia, hypercapnia
CXR - hyper expanded lungs, bullae
RFTs- Decreased FEV1/FVC ratio, normal/increased TLC, Decreased DLCO
ECG - Right heart strain, RVH, P pulmonale (large P wave in V1)

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3
Q

What criteria is used to assess severity of COPD?

A

GOLD
A, B E = Symptoms (CAT or mMRC) + Exacerbation history (>2 moderate or 1 hospital admission = E)

Stages (all have FEV1/FVC <0.7)
1 = mild, FEV1 >80%
2 = moderate, FEV1 = 50-80%
3 = Severe, FEV1 = 30 - 50%
4 = very severe, FEV1 <30%

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4
Q

What is the medical mx of COPD?

A
  • Smoking cessation
  • Bronchodilators (b2, anticholinergics)
  • Inhaled + systemic corticosteroids
  • Vaccinations
  • Oxygen therapy (aiming PaO2 60-80mmHg)
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5
Q

What is the surgical options for Mx of COPD?

A
  • Bullectomy
  • Lung volume reduction surgery (no survival benefit)
  • Lung Tx
  • Endobronchial valves
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6
Q

What are the anaesthetic goals in COPD?

A

-Optomise resp function preop
- Pro-expiratory ventilation and monitoring for gas trapping
- Optomisition for extubation

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7
Q

What are the diagnostic criteria for RVH on ECG?

A
  • RAD
  • QRS <0.12secs
  • Dominant R wave in V1 >7mm
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8
Q

What is bronchiectasis?

A

Chronic suppurative disease of the airways that can cause expiratory airflow obstruction

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9
Q

What are the causes of bronchiectasis?

A

o Congenital – cystic fibrosis
o Acquired – lung infections, localised airway obstruction, inflammation

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10
Q

What are clinical features on history of bronchiectasis?

A
  • Fever
  • Cachexia
  • Clubbing
  • Sputum
  • Pan inspiratory crackles over affected lobe
  • Signs of right heart failure
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11
Q

What is kartagener syndrome?

A

inherited ciliary dyskinesia = triad of bronchiectasis, sinusitis + situs inversus

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12
Q

What are the Ix findings in bronchiectasis?

A

FBC - anaemia of chronic disease, leukocytosis
CXR - hyperinflation, collapse in segments
PFTs - obstructive pattern followed by mixed pattern as disease progresses

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13
Q

What is the medical mx of bronchiectasis?

A
  • Smoking cessation
  • Antibiotics to prevent and treat infections
  • Mucolytic agents
  • Inhaled bronchodilators
  • Vaccinations
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14
Q

What are some anaesthetic goals in bronchiectasis?

A
  • Optomise preop - may need preop antibiotics, steroids or physio
  • Intubation required for secretion management if GA
  • Can consider DLT if unilateral bronchiectasis
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15
Q

What is asthma?

A

chronic airway inflammation, reversible expiratory airflow obstruction in response to various stimuli & bronchial hyperreactivity

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16
Q

What some exam findings in asthma?

A
  • Wheeze
  • Tachypnoea
  • Dry/productive cough
  • Prolonged forced expiratory time
  • Hyperinflated lungs
17
Q

What are some Ix findings in asthma?

A
  • ABG - either normal or if asthma attack then decreased CO2 and resp alkalosis
  • PFTs - Obstructive pattern with bronchodilator responsiveness
  • CXR - hyperinflation
  • ECG - tachycardia
18
Q

How do you classify severity of asthma?

A

Two ways:
Amount of treatment required for good control:
- Daytime symptoms <2 days/week
- Need for reliverer <2 days/week
- No Limitation of acitivity
- No Symptoms during night or waking

Good control is all of the above
Partial control is 1-2
Poor control is >2

FEV1 % predicted measurements is other way
Mild = 65-80
Moderate = 50-65
Severe = 35-50
Very severe = <35

19
Q

What are some anaesthetic goals with asthma?

A
  • Aim to suppress bronchospasm:
    Avoid histamine releasing drugs
    LMA better than ETT
    Preop ventolin
    Smooth extubation
    Use volatile
  • Pro expiratory ventilation
    Long I:E ratio
    TV 8mls/kg
    RR 6-8
    avoid PEEP
    Permissive hypercapnia
20
Q

What are the types of restrictive lung disease?

A

Acute intrinsic - pulm oedema, ARDS, aspiration
Chronic intrinsic - Sarcoidosis, pulm Fibrosis
Chronic extrinsic - deformities of skeletal system, mediastinal mass, neuromuscular disorders

21
Q

What are exam findings in restrictive lung disease?

A
  • Chest wall deformity (depending on cause)
  • Fine crackles if intersitial lung disease
  • Cor pulmonale - RV heave, Loud P2
22
Q

What are some Ix findings in restrictive lung disease?

A

FBE - polycythaemia
ABG - hypoxaemia
PFT - decrease in all lung volumes, normal FEV1/FVC
DLCO - decreased in intrinsic disease, normal in extrinsic disease

23
Q

What scoring system is used in pneumonia?

A

CURB -65

Confusion
Urea > 7
Resp rate >30
BP <90 sys

Age >65

Score >1 = inpatient treatment

24
Q

What is apnoea defined as?

A

cessation of breathing for longer than 10 seconds

25
What is a hypopnoea defined as?
No agreed definition. reduction in size or number of breaths compared with normal ventilation >30% airflow reduction with associated 4% desat is one definition
26
What Ix do can you see in OSA?
FBE - polycythemia ABG - hypercapnia, raised bicarb (OHS if >30) ECG - Right heart strain, RVH, Right atrial enlargement (P wave large in V1) Sleep study - AHI >5 = mild, >15 = moderate, >30 = severe
27
What are some anaesthetic goals with OSA?
- Continue CPAP throughout admission - Avoid sedating drugs preop - Avoid long acting opioids, use regional - Anticipate difficult BMV - Post op monitoring (HDU or 24hr continous pulse ox)
28
What is Obestity hyperventilation syndrome?
nocturnal episodes of central apnoea (apnoea without respiratory efforts) reflecting progressive desensitization of the respiratory centre to nocturnal hypercarbia
29
What is cystic fibrosis?
Autosomal recessive genetic disorder with variable expression
30
What are the clinical features of cystic fibrosis?
- Pulmonary obstructive disease - Non pulmonary disease - diabetes, pancreatic insufficency, liver disease
31
What Ix do you see in cystic fibrosis?
- Bloods - anaemia of chronic disease, BSL for diabetes, LFTs - ABG - hypoxia and hypercapnia - ECG - RAD, RBBB - TTE - evidence of cor pulmonale - PFTs - obstructive pattern with decrease in both FEV1 and FEV1/FVC
32
What are some anaethetic goals with cystic fibrosis?
- Optomise prior to surgery - Regional preferred to avoid airway management - LMA may be beneficial although cannot suction secretions - Avoid nasal intubations - Ventilate with pro-expiratory settings but also avoid high pressures
33
What is pancoast syndrome?
neoplasm of superior lung with involvement of brachial plexus (arm/hand wasting + pain), cervical sympathetic nerves (Horner’s Syndrome), compression of blood vessels + oedema
34
What is the preop assessment of lung function in lung ca?
3 legged stool: 1. Respiratory mechanics – PPO FEV1 >40% - minimal risk; <30% high mortality risk 2. Cardiopulmonary testing – VO2 max >15mls/kg/min acceptable = 600m on 6MWT = ~4METS. VO2max <10mls/kg/min absolute contraindication 3. Lung parenchymal function – PPO DLCO >40% good outcome; <30% non-survival BTS guidelines - if both ppofev1 and dlco <40 % = high risk. Both >40% then average risk. In between then needs exercise testing
35
How do you decide on post thoracotomy anaesthetic extubation?
ppoFEV1% >40% = extubate 30-40% = depends on exercise tolerance, DLCO, comorbidities <30% = staged weaning in ICU