respiratory Flashcards
(27 cards)
1
Q
parts of conductive system
A
nasal cavity, pharynx, larynx, trachea, bronchi
2
Q
parts of transitional system
A
terminal bronchioles
3
Q
parts of gas exchange system
A
respiratory bronchioles and alveoli
4
Q
non-specific immune response
A
- mucous trapping
- mucociliary clearance
- phagocytosis
- air turbulence- generated by coughing and sneezing
5
Q
specific immune response
A
- antibody production
- antibody-mediated phagocytosis
- cell- mediated immunity
6
Q
- respiratory region of nasal cavity (largest part)
A
- respiratory portion lined by psuedostratified columnar epithelium with goblet cells
- lamina-propria contains tubulo-alveolar glands- mainly serous with lesser numbers of mucous and mixed glands
- conchae turbinates
7
Q
- vestibular region of nasal cavity
A
- initial, external part of nasal cavity
- lined by haired skin and glands
- stratified squamous keratinized epithelium
8
Q
- olfactory region of nasal cavity
A
- lined with olfactory epithelium, lacks goblet cells
- has neurons, supporting cells. basal cells
- along with respiratory region contain venous plexus with swell bodies
9
Q
mucociliary apparatus
A
- pseudostratified ciliated columnar epithelium
- goblet cells– produce mucinogen granules
- movement of cilia removes mucus with trapped airborne inhaled particles such as dust and microorganisms
- cleaning apparatus of upper respiratory passages
10
Q
larynx
A
- includes cartilage, vocal folds, skeletal muscle
- initial part of larynx=stratified squamous epithelium
- after vocal cords changes to pseudostratified ciliated columnar epithelium
11
Q
trachea
A
- lined by ciliated psuedostratified columnar epithelium
- lamina propria and submucosa are clearly not demarcated
- serous glands in lamina propria/submucosa
- cartilagenous rings
- connective tissue adventitia
12
Q
bronchus
A
- ciliated pseudostratified columnar epithelium
- smooth muscle, lamina propria, mixed bronchiole glands
- plates of hyaline cartilage
13
Q
bronchioles
A
- lack cartilage and glands
- terminal
- respiratory
14
Q
terminal bronchioles
A
- lined by ciliated cuboidal cells- few to no goblet cells
- muscularis mucosae
15
Q
club “Clara” cells
A
- in terminal and respiratory bronchioles
- bulge at surface
- secrete surfactant-like substance which aids in maintaining patency of airway
- may have immune function
16
Q
respiratory bronchioles
A
- ciliated cuboidal epithelium
- incomplete muscularis mucosae
- subdivide into alveolar ducts
17
Q
alveolar ducts
A
- exchange system
- empty into alveolar sacs and alveoli
- walls are lined with simple squamous epithelial cells
- opening surrounded by smooth muscle
- empty into alveolar sacs and alveoli
18
Q
alveolar sacs
A
- branch from alveolar sacs, lack smooth muscle
- lined by epithelial cells: Pneumocytes type I and pneumocytes type II
19
Q
alveolar pores of Kohn
A
- neighboring alveoli connect via pores, equalization of pressure and collateral ventilation
- pores allow macrophage passage from one alveolus to another
20
Q
alveolar septum and interstitium
A
- fibroblasts and capillaries
- collagen type 3
- collagen type 1 always present in conducting airways
- elastic fibers
21
Q
pneumocyte type 1- squamous alveolar type 1 cell
A
- form walls of alveoli
- 95% alveolar surface area
- thin with occluding junctions to prevent fluid passage
- not mitotic
22
Q
pneumocyte type II- granular alveolar type II cell
A
- 5% alveolar surface area
- secretory cell
- lamellar bodies produce surfactant
- can be mitotic and produces type 1 and 2 cells
23
Q
surfactant
A
- phospholipoprotien
- reduces surface tension
- produced by type II cells
- cortisol stimulates production of surfactant in fetus
24
Q
Air-Blood barrier
A
- cytoplasm of pneumocyte type I covered by surfactant
- two fused basal laminae of alveolar epithelium and endothelium of capillary
- endothelium
25
interalveolar septum
1. granular pneumocyte= great alveolar cell pneumocyte type II
- granules of surfactant
- surfactant on surface of alveolar lining
- cytoplasm of pneumocyte type I
- pneumocyte type 1
26
pulmonary macrophages
- alveolar macrophages (PAMS)
| - intervascular macrophages (PIMS)
27
pleura
- thoracic wall, diaphragm and mediastinum lined by parietal pleura, continuous with mediastinal and visceral pleura covering surfaces of lungs
- pleura is composed of simple squamous epithelial cells- mesothelial cells