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Anesthesia: Basic > Respiratory > Flashcards

Flashcards in Respiratory Deck (13):
1

What is oxygen consumption in an adult?

3 mL/kg/min

2

What causes R shift of CO2 response curve

narcotics
chronic obstruction
metabolic alkalosis
volatile agents

3

What are peripheral vs central chemoreceptors?

peripheral = O2 triggered
1) carotid body (CN9), ventillatory effects, pick up PaO2 60-65
2) aortic arch/bodies (CN10), circulatory effects

central = medulla = CO2, triggered by CSF and respiratory acidosis

inhibited by volatile anesthetics

4

What causes L shift of CO2 response curve?

metabolic acidosis
doxapram / dopram = respiratory stimulant
hypoxemia

5

What decrease the slope of the CO2 response curve?

benzodiazepines
propofol
volatiles (decrease slope and R-shift)

6

how do you calculate anion gap?

(Na + K) - (Cl + HCO3)
normal 8-12

7

What are the direct inhibitors of HPV?

hypocarbia
infection
vasodilators (nitroglycerin, nicardapine, nitroprusside)
metabolic alkalosis
volatile anesthetics MAC > 1

8

what is the alveolar gas equation?

PAO2 = PiO2 - PaCO2/R

PiO2 = FiO2*(Pbar - PH2O)

9

What is the rise in bicarb for acute vs chronic respiratory acidsosis

acute = 0.2 mmol/L for each 1mmHg rise in CO2 above 40
chronic = 0.4 mmol/L

10

how does the effect of PEEP change in a normal patient vs patient w/ CV

peep increased intra-thoracic pressure and RV afterload

normal patient = decreased pre-load and CO
CHF patient = volume overloaded, decreased pre-load is good, reduced LVEDP, decreased afterload

11

When does FRC drop the most?

from upright 60deg to flat 0deg

from flat 0deg to -30deg T-berg

12

what decreases closing capacity?

ACLSS
Age
Chronic Bronchitis
LV failure
Smoking
Surgery

13

smoking cessation effects

- 24-48hrs: R shift carboxyhemoglobin curve
- 2 weeks: worsens ciliary function and sputum production
- 2 to 3 months: improved cilia, less secretions, improved closing volume, increased FEF25-75%