Flashcards in Respiratory Deck (13):
What is oxygen consumption in an adult?
What causes R shift of CO2 response curve
What are peripheral vs central chemoreceptors?
peripheral = O2 triggered
1) carotid body (CN9), ventillatory effects, pick up PaO2 60-65
2) aortic arch/bodies (CN10), circulatory effects
central = medulla = CO2, triggered by CSF and respiratory acidosis
inhibited by volatile anesthetics
What causes L shift of CO2 response curve?
doxapram / dopram = respiratory stimulant
What decrease the slope of the CO2 response curve?
volatiles (decrease slope and R-shift)
how do you calculate anion gap?
(Na + K) - (Cl + HCO3)
What are the direct inhibitors of HPV?
vasodilators (nitroglycerin, nicardapine, nitroprusside)
volatile anesthetics MAC > 1
what is the alveolar gas equation?
PAO2 = PiO2 - PaCO2/R
PiO2 = FiO2*(Pbar - PH2O)
What is the rise in bicarb for acute vs chronic respiratory acidsosis
acute = 0.2 mmol/L for each 1mmHg rise in CO2 above 40
chronic = 0.4 mmol/L
how does the effect of PEEP change in a normal patient vs patient w/ CV
peep increased intra-thoracic pressure and RV afterload
normal patient = decreased pre-load and CO
CHF patient = volume overloaded, decreased pre-load is good, reduced LVEDP, decreased afterload
When does FRC drop the most?
from upright 60deg to flat 0deg
from flat 0deg to -30deg T-berg
what decreases closing capacity?