respiratory emergencies Flashcards

1
Q

what immunological response causes anaphylaxis?

A

IgE -> antigen -> mast cells and basophils -> histamine increases -> body response

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2
Q

what are the symptoms of anaphylaxis?

A
  • pruritus
  • urticaria and angioedema
  • hoarseness, progressing to stridor and bronchial obstruction
  • wheeze and chest tightness from bronchospasm
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3
Q

how do you treat anaphylaxis?

A
  • remove trigger, maintain airway, 100% o2
  • intramuscular adrenaline 0.5mg, repeat every 5 mins as needed to support CBS
  • IV hydrocortisone 200mg
  • IV chlorpheniramine 10mg
  • hypotensive, lie flat and fluid resuscitate
  • treat bronchospasm with NEB salbutamol
  • treat laryngeal oedema with NEB adrenaline
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4
Q

what are the signs of a life threatening asthma attack?

A
  • peak expiratory flow less than 33% of best
  • Sats <92% or ABG pO2 < 8 kPa
  • cyanosis poor respiratory effort, near or fully silent chest
  • normal pCO2
  • exhaustion, confusion, hypotension or arrhythmias
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5
Q

how would you manage an acute asthma attack?

A

ABCDE approach

aim for sp02 94-98%, ABG if sats <92%

5mg nebuliser salbutamol, can repeat after 15 minutes

40mg oral prednisolone STAT (IV hydrocortisone if PO not possible)

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6
Q

how would you treat a severe asthma attack?

A
  • Nebulised ipratropium bromide 500mg

- consider back to back salbutamol

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7
Q

how would you manage a life threatening/near fatal asthma attack?

A
  • urgent ITU or anaesthetic assessment
  • urgent portable CXR
  • IV Aminophylline
  • consider IV salbutamol if nebuliser route ineffective
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8
Q

what are the types of COPD exacerbations?

A
  • infective = change in sputum volume/colour, fever, raised WCC +/- CRP
  • non infective
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9
Q

how would you approach a patient with a COPD exacerbation?

A

ABCDE approach

  • oxygen via fixed performance mask due to risk of CO2 retention
  • aim for SaO2 88-92% being guided by ABGs
  • NEBs = salbutamol and ipatropium bromide
  • steroids - prednisolone 30mg STAT and OD for 7 days
  • antibiotics if raised CRP/WCC or purulent sputum CXR
  • consider IV aminophylline
  • consider NIV if type 2 res failure and pH 7.25-7.35
  • If pH <7.25 consider ITU referal
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10
Q

what would indicate pneumonia in a patient?

A

consolidation on CXR with fever +/- purulent sputum, +/ raised WCC and/or CRP

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11
Q

how would approach a patient with suspected pneumonia?

A

ABCDE

  • any features of sepsis, immediately treat using sepsis pathway
  • otherwise treat with antibiotics as per CURB-65 score, local pneumonia guidelines and patient allergies
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12
Q

what is the CURB-65 score?

A

helps treat pneumonia by scoring the patients symptoms

C = confusion, MMT 2 or more points worse

U = Urea >7.0

R = >/= 30/min

B = <90 mmHg systolic or <60 mm Hg diastolic

65 = above 65 years old

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13
Q

what is massive haemoptysis?

A

> 240mls in 24hrs

OR

> 100mls/day over consecutive days

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14
Q

how do you manage a massive haemotypsis?

A
  • ABCDE
  • lie patient on side of suspected lesion
  • Oral tranexamic acid for 5 days or IV
  • stop NSAIDs/Asprin/Anti-coagulants
  • antibiotics if any evidence of respiratory tract infection
  • consider vitamin K
  • CT aortogram - interventional radiologist may be able to undertake bronchial artery embolism
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15
Q

what are the signs of tension pneumothorax?

A
  • hypotension
  • tachycardia

on CXR

  • deviation of trachea away from the side of the pneumothorax
  • mediastinal shift away from pneumothorax
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16
Q

how do you treat a tension pneumothorax?

A
  • large bore intravenous cannula into 2nd ICS MCL

- chest drain into affected side

17
Q

what are the symptoms of a PE?

A
  • pleuritic chest pain
  • SOB
  • haemoptysis
  • low CO followed by collapse (if massive PE)
18
Q

what are the risk factors for getting a PE?

A
  • post surgically, e.g abdominal/pelvic, knee/hip replacement
  • obstetric e.g late pregnancy or c section
  • lower limb e.g fracture or varicose veins
  • malignancy e.g abdominal/pelvic/advanced/metastatic
  • reduced mobility
  • VTE
19
Q

What is the management of a PE?

A

ABCDE

  • oxygen if hypoxic
  • fluid resuscitation if hypotensive
  • thrombosis if a massive PE is confirmed on echo or CT scan
  • patient should be fully anti coagulated
20
Q

how would you treat a massive PE?

A
  • suspect if hypotensive/imminent cardiac arrest
  • signs of right heart strain on CT/Echo
  • consider thrombosis with IV alteplase
21
Q

what are the contraindications of thrombolysis, both absolute and relative?

A

Absolute

  • haemorrhage or ischaemic stroke less than 6 months ago
  • CNS neoplasia
  • recent trauma or surgery
  • GI bleed <1 month
  • bleeding disorder
  • aortic dissection

relative

  • warfarin
  • pregnancy
  • advanced liver disease
  • infective endocarditis
22
Q

what are the complications of thrombolysis?

A
  • bleeding
  • hypotension
  • intracranial haemorrhage/stroke-
  • repercussion arrhythmias
  • systemic embolisation of thrombus
  • allergic reaction