Respiratory Foundations 1 Flashcards

1
Q

Upper Respiratory System

A

Nasal Cavity -> Pharynx -> Larynx

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2
Q

Lower Respiratory System

A

Trachea -> Primary Bronchi -> Smaller Bronchi -> Bronchioles -> Alveoli

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3
Q

Respiratory System Function

A
  1. Gas exchange
  2. Homeostatic regulation of body pH (CO2)
  3. Conditioning Inspired Air
  4. Protection (filtering/clearing foreign particles)
  5. Vocalization
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4
Q

pH affect Equation

A

H2O + CO2 = H2CO3 = H+ + HCO3-

H2CO3 = carbonic anhydrase (weak acid that dissociates)

  • increased carbon dioxide leads to an increased internal acidity
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5
Q

External Respiration Steps

A
  1. Atmosphere to lung
  2. Lung to blood
  3. Transport of gases in blood
  4. blood to cells (cellular respiration occurs here)
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6
Q

Thoracic Cavity Pressure Gradient

A

expansion/contraction of the thoracic cavity creates a pressure gradient for air to move accordingly

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7
Q

Ventilation Muscles at rest

A
  1. External Intercostals
  2. Diaphragm
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8
Q

Forced Inspiration Muscles

A
  1. Sternocledio mastoids
  2. scalenes
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9
Q

Forced Expiration Muscles

A
  1. Internal intercostals
  2. abdominal muscles
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10
Q

Pleural Membranes

A
  • fluid filled balloon that wraps around the lungs, sticks to the lungs and the thoracic cage
  • made up of secretory epithelial cells
  1. Visceral = against the lung
  2. Parietal = against the thoracic cage
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11
Q

Airways Role

A
  1. filter our foregin substances
  2. warm air to body temperature
  3. add water vapour
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12
Q

Cartilage effect on airways

A
  • trachia/bronchi have cartilage and are unable to change diameter
  • bronchioles have no cartilage and are able to change diameter due to neural/hormonal/paracrine effects
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13
Q

Site of Gas exchange

A

Alveoli

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14
Q

ANS effect on bronchiole radius

A

SNS - bronchodilate
PSNS - bronchoconstrict

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15
Q

Ciliated Epithelium of the respiratory tract

A
  • cilia move the mucus layer towards the pharynx, removing pathogens
  • Mucus layer traps particles
  • watery saline allows cilia to push towards the pharynx
  • Goblet cells secrete mucus
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16
Q

X-Sectional Area affect on resistance

A

trachea has smallest x-sectional area, therefor largest resistance
bronchioles has largest x-sectional area, therefor smallest resistance

17
Q

Modulation of Bronchiolar Radius: increased CO2

A
  • paracrine response that causes broncodilation
18
Q

Modulation of Bronchiolar Radius: SNS

A

NE & E bind to Beta2 adrenergic receptors
- increased blood to skeletal muscles
- decreased blood to GI Tract
- causes the relaxation of bronchiole smooth muscle
-Gs pathway

19
Q

Modulation of Bronchiolar Radius: Histamine

A

paracrine response causing bronchoconstriction

20
Q

Modulation of Bronchiolar Radius: PSNS

A

ACh binds to M3 muscarinic receptors causing the constriction of bronchiole smooth muscle
-Gq pathway

21
Q

Alveoli Cell Type

A

secretory epithelial cells

22
Q

Type 1 Alveolar Cells

A
  • gas exchange
  • 95% of SA
23
Q

Type 2 Alveolar Cells

A
  • make and secrete surfactant