Respiratory Pharmacology Flashcards

1
Q

indicated for treatment of acute episodes of bronchospasm

A

short-acting beta agonist

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2
Q

what are the short acting beta agonist?

A

albuterol

levalbuterol

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3
Q

indicated for long term control of bronchospasm in the patients asthma and COPD

A

long acting beta agonist

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4
Q

what are the long acting beta agonist?

A

salmeterol
formoterol
arformoterol

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5
Q

what are the side effects of beta-adrenergic bronchodilators?

A
tremors
tachycardia
palpations
hypertension
headache
paradoxical hypoxemia
tachyphylaxis
nausea
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6
Q

drugs that work against the bronchoconstriction caused by the parasympathetic nervous system (decreases cGMP)

A

anticholinergic (parasympatholytics)

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7
Q

act by blocking cholinergic parasympathetic receptors

A

anticholinergics

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8
Q

what are the anticholinergic drugs?

A

ipratropium

tiotropium

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9
Q

what can be delivered with the anticholinergics bronchodialators?

A

SABA

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10
Q

this inhibitor drug increases the amount of cAMP within the smooth muscle. increases the level of cAMP that causes bronchodialation

A

methylxanthines

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11
Q

what are the methylxanthine drugs?

A

theophylline
caffine
theo-dur

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12
Q

what are the side effects of theophylline?

A
tachycardia
palpations
jutters
irritability
diuresis
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13
Q

anti-inflammatory agents with direct and indirect bronchodilation effects

A

corticosteroids

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14
Q

what are some of the corticosteroid drugs?

A

fluticasone
beclomethasone
budesonide
prednisone

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15
Q

recommended when secretions are thick and tenacious and cannot be easily removed

A

mucolytics

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16
Q

what is the mucolytic for CF?

A

pulmozyme

17
Q

specifically dilate the pulmonary blood vessels

A

pulmonary vasodilators

18
Q

what are the indications for pulmonary vasodilators?

A

PHTN
ARDS
R ventricular failure/ cor pulmonale

19
Q

non steroid drugs that have been approved for patients with mild to moderate persistent asthma

A

leukotriene

20
Q

what are the leukotriene medications?

A

montelukast
zafirlukast
zileuton

21
Q

will help prevent an asthma attack by inhibiting the degranulation of mast cells and preventing the release of histamine and leukotrienes

A

mast cell satbilizers

22
Q

what are some mast cell stabilizers?

A

cromolyn sodium

nedocromil sodium

23
Q

beta 2 does what?

A

bronchodialation

24
Q

beta one does what?

A

increase heart rate (vasoconstriction)

25
Q

alpha one does what

A

vasoconstriction

26
Q

the autonomic nervous system includes the ?

A

sympathetic

parasympathetic

27
Q

what are the sympathetic ns receptors?

A

beta 1
beta 1
alpha 1

28
Q

what are the parasympathetic ns receptors?

A

muscinaric

nicotinic

29
Q

the (sympathetic) controls which hormones ??

A

epinephrine

norepinephrine

30
Q

the cholinergic (parasympathetic) controls which hormones?

A

muscinaric

nicotinic

31
Q

what is the formula for clarks rule?

A

(lbs/150) x adult dose

32
Q

what is the formula for youngs rule?

A

(age/age+12) x adult dose

33
Q

what is formula for frieds rule?

A

(age in months/150) x adult dose