Respiratory Physiology Flashcards

(51 cards)

1
Q

state the primary functions of the respiratory system

A

-gaseous exchange between air and blood
-regulates blood pH
-regulates blood pressure (by producing angiotensin converting enzyme)

-vocalisation (speech)
-olfaction (smell)
-protection of respiratory surface from dehydration, temperature changes and pathogens.

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2
Q

name the anatomical structures/divisions of the respiratory system

A

-upper respiratory tract (nasal cavity, pharynx (conducts air and food)
-lower respiratory tract (larync to lungs (air only)

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3
Q

name the physiological divisions of respiritaory and their function

A

CONDUCTING ZONE
-conducts air towards lung (nose, pharynx, larynx, trachea, bronchi, bronchioles, terminal bronchioles)
RESPIRATORY ZONE
-functional zone involves in respiration (respiratory bronchioles, alveolar ducts, alveolar sacs, alveoli)

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4
Q

what are the histological features adapted to conducting zone

A

respiratory epithelium with mucous cells and the muco-ciliary escalator lines nasal cavity and superior portion of the pharynx. (mainly lined by respiratory epithelium)

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5
Q

what are the histological features of the respiratory zone/finer bronchiols.

A

epithelium becoes cuboidal

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6
Q

what are the histological features of gas exchange surfaces.

A

delicate simple squamous epithelium-the distance between the air and the blood in adjacent capillaries is generally less than 1 micrometre.

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7
Q

describe “pseudostratified” epithelium

A

describes closely packed cells which appear to be in multiple layers (stratified) but are, in fact, all attatched at basement memmbrane

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8
Q

describe “ciliated” epithelium

A

cilia are tiny hairs on surface of epithelium cells which sweep mucous/debris

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9
Q

describe “columnar epithelium”

A

epithelial cells appear like tall columns

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10
Q

describe goblet cells

A

produce mucous which trap particles

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11
Q

define the functions of the external nose and nasal cavity structure

A

Air Conditioning
-the air outside is dry and cold and so must be moistured and heated
Filtration
-the vestibule of the nose is lined with skin which hairs to trap pollen, pathogens dust ect (contains respiratory epithelium)
Olfaction
-directs air upwards towards the olfactory nerve speech
Vocalisation
-modifies speech vibrations, adds resonance

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12
Q

state the properties of the trachea

A

-windpipe (15cm long, 2.5cm wide)
-anterior to oesophagus
-distally it bifucrates into left and right primary bronchi
-c-shaped cartilages to keep trachea patent
lined by respiratory epithelium

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13
Q

describe the bifucration of the trachea

A

-left and right primary bronchi are seperated by CARNIA, the last tracheal cartilage
-carnia is sensitive to mechanical stimuli and stimulates power cough reflex
-right main bronchus is wider and more vertical than left

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14
Q

describe the structure of the bronchial tree

A

PRIMARY BRONCHI
-left and right
-cartilage rings
SECONDARY BRONCHI
-lobar branch
-2 left, 3 right (mirror lobes of lungs)
-cartilage plates (incomplete rings)
TERTIARY BRONCHI
-segmental
-one to eaxh segment of lung
-cartilage segments
BRONCHIOLS
-no cartilage
-smooth muscle in walls
TERMINAL BRONCHIOLS
-end of conducting zone
-simple cuboidal epithelium
RESPIRATORY BRONCHIOLS
-start of respiratary zone

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15
Q

describe the structure of alveolar sacks

A

-respiratory bronchiols connect to alveolar ducts
-alveolar sacks are the “bunch of grape-like” structures at distal ends of alveolar sacks
-have very large surface area (500million alveioli in adult lungs)
-surrounded by vast capilary netwrok

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16
Q

describe the alveoli

A

-the end point of respiaratory system
-ballon shaped structure
-site of gaseous exchange by diffusion across alveolar and capillary wall.

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17
Q

describe the structure of the lungs

A

-lungs occupy most of thoracic cavity
-extend into root of neck
-LEFT lung has 2 loes (superior/inferior) and one fissure (oblique) due to cardiac notch (space for the heart)
-RIGHT lung has three lobes (superior/inferior/middle) and two fissures (oblique and horizontal)

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18
Q

define the “hilium” of the lungs

A

the “root of lung” point of which a collection of structures enter and leave the lungs.
bronchi/pulmonary artery/pulmonary veins/lymphatics/nerves

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19
Q

what structures line/surround round the lung

A

-surrounded pleural membrane
-a continuous membrane with potential space between
-categorised as parietal pleura/visceral pleura.

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20
Q

what is the thoracic cage comprised of

A

-ribs
-sternum,manubrium and costal cartilage
-thoracic vertebrae T1-T12

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21
Q

what is the function of thoracic cage

A

-protects viscera
-attatchment site of muscles of respiration
-facilitates respiration

22
Q

describe the “mechanism of respiration”

A

-diaphragm contracts, increasing the volume of thoracic cage
-air is then drawn into the lungs when pressure inside lungs (alveolar pressure) is less than atmospheric pressure (high-low)

23
Q

describe the INSPIRATION stage in respiration

A

thoracic cavity expands—lungs expands–interpulmonary pressure decreases=draws air in

24
Q

what sort of transport does inspiration require

A

active: requires energy for muscle contraction

25
describe the EXPIRATION stage of respiration
thoracic cavity volume decreases---lungs contract---interpulmonary pressure increases=air explelled
26
what type of transport does expiration require
passive-elastic recoil
27
describe the strcture/function of the diaphragm
-large dome-shaped musculotendinous sheet -seperated thorax from abdomen -main muscle of respiration
28
describe the action of the diaphragm
contraction-descends, flattens to increase size of thoracic cavity during inspiration relaxation-ascends into dome-shape to decrease size of thoracic cavity upon expiration(passive)
29
describe the structure of intercostal muscle
-lie between the ribs (in the intercostal spaces) -external intercostal muscles elevate ribs during inspiration
30
discuss the accessory muscles of respiration
they do not play a primary role in breathing, may be used in laboured/deep breathing. if used at rest a sign of respiratory distress
31
what is the primary function of the lungs and how does it occur
gas exchange occuring by diffusion
32
what does the rate of transfer in gas exchange depend on
-the area -the distance -the concentration difference (driving force) the area should be as large as possible, diffusion distance should be as small as possible
33
Discuss oxygen transport in the body
Once oxygen is exchanged in the lungs it is carried in blood in 2 forms -by red blood cell bound to haemoglobin (97-98%) -dissolve in plasma
34
how many haemoglobin molecules are in the body
280million
35
why is binding dissociation of O2 with Hb so fast
facilitate transport-necessary because red blood cells are in capillaries for 1 second
36
how many O2 atoms can Hb bond to
bind upto four O2 atoms
37
what does O2 saturation (SaO2) refer too
amount of O2 bounf to Hb relative to maximal amount that can bind
38
what does it mean if a person has 100% saturation
all heme groups of Hb molecules full saturated with O2
39
what is a pule oximeter used for
-continuous monitoring critical care, anaesthesia -screening for apnoea -detecting hypoxia in pilots
40
discuss CO2 production
in normal healthy conditions -200ml CO2/min produced -80 molecules CO2 expired by lung for every 100 molecules of O2 entering
41
describe carbon dioxide transport
CO2 diffuses into blood stream (diffusion) -7% dissolves in the plasma -23% bound to haemoglobin -70% converted to biocarbinate
42
what is a spirometer used for
measuring function -when the subject inhales air moves into lungs -volume of bell decreases, pen rises on training
43
describe the respiratory condition asthma and the symptoms
a chronic inflammatory disease that causes breathing problems, when airways become narrowed by inflamation or blocked by mucous symptoms -wheezing -coughing -tightness of chest -shortness of breathe
44
what is a treatment for astma
salbutamol inhaler
45
describe the respiratory disease chronic obstruction pulmonary disease (COPD)
an umberella term used to describe two primary types of obstructive lung disease 1.emphysema 2.bronchitis
46
name the symptoms of (COPD)
frequent coughing wheezing cough produces lots of mucous shortness of breathe tightness of chest weakness weight loss swelling of legs amd feet
47
describe some of the treatment for COPD
cessation of smoking stayong up to date in important vaccines combination therapy bronchodilater anti-inflammatory therapy
48
describe the respiratory condition cystic fibrosis
-a genetic condition that can cause both digestive and breathing problems because the disease makes mucous in the body thick -the disease can cause specific problems in the lungs such as blockages from thick mucous, trapping harmful bacteria leading disease
49
what are symptoms of cystic fibrosis
a cough that does not go away wheezing shortness of breathe coughing thick mucous blood constipation
50
what are treatment for cystic fibrosis
-medication-antibiotics, steroids, bronchodilaters -excersise -airway clearence techniques -active cycle breathing techniques diet and nutrition- high calorie lung transplant
51
describe sleep apnoea
normal airway-airway is open and air moves through obstructive sleep apnoe-airway is blocked and air does not move through