Respiratory physiology 3 Flashcards

1
Q

What is tidal breathing?

A

Normal relaxed breathing. 500 mL.

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2
Q

What is inspiratory reserve volume IRV ?

A

Volume that we can breath in on the top on tidal volume. It is 3000 mL.

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3
Q

What is expiratory reserve volume ERV?

A

Volume that we can breath out on the top of normal expiration. It is 1100 mL.

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4
Q

What is vital capacity VC?

A

Maximum amount of air that can be shifted in one breath, tidal breathing + IRV + ERV. It is equal to 4600 mL.

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5
Q

What is residual volume RV?

A

The amount of air that can’t be exhaled from lungs. It is equal to 1200 mL.

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6
Q

What is functional residual capacity FRC?

A

The amount of air left in the lungs after normal tidal breathing. RV +ERV It is equal to 2300 mL.

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7
Q

What is total lung capacity?

A

The amount of air that can be in the lungs, VC + RV. It is equal to 5800 mL

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8
Q

What is the role of residual volume?

A

Prevents alveoli from collapsing and enables gas exchange to occur all the time.

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9
Q

On which lung values has anaesthetic impact?

A

On functional residual capacity. It also prevents bronchioles from collapsing.

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10
Q

Why does lung function with age deteriorate?

A

As we age our muscles get weaker and the lungs become less elastic.

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11
Q

Why is the first breath the hardest one?

A

Because babies need to inflate the alveoli and fill the residual volume.

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12
Q

What is anatomical dead space?

A

The air in conducting airways, it is usually 150 mL.

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13
Q

How much of fresh air reaches the alveoli?

A

Only 350 mL, 150 mL stays in the conducting airway. Therefore only 70% is available for gas exchange.

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14
Q

What is stale air?

A

The alveolar air that fills the anatomical dead space on expiration.

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15
Q

What is ventilation?

A

Movement of air in and out of lungs.

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16
Q

What is pulmonary ventilation?

A

The total amount of air moved, it is product of tidal volume and respiratory frequency.

17
Q

What is alveolar ventilation?

A

Fresh air that reaches the alveoli, tidal volume - anatomical dead space x respiratory frequency.

18
Q

What has bigger impact in the alveolar ventilation, rate or depth of breathing?

A

Depth of breathing.

19
Q

What happens in hypoventilation?

A

Rapid and shallow breathing, PO2 falls to about 30 mm Hg, and PCO2 raises to about 100 mmHg.

20
Q

What happens in hyperventilation?

A

Rapid and deep breathing, PO2 raises to about 120 mm Hg, PCO2 falls to about 20 mmHg

21
Q

Why is alveolar partial pressure of O2 different from atmospheric?

A

This is due to the residual volume and dead space that dilute the oxygen, also as we breath in the air gets humidified and this changes O2 solubility. In addition there is content gas exchange and so the alveolar PO2 is in equilibrium with arterial PO2.

22
Q

What is the partial pressure of O2 and CO2 in alveoli ?

A

PO2 = 100 mm Hg, PCO2 = 40 mmHG