Respiratory tract infection Flashcards

(44 cards)

1
Q

Give 4 conditions of the upper tact

A

Common cold - coryza
Sore throat - pharyngitis
Sinusitis
Epiglottitis

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2
Q

Give 4 conditions that can affect the lower respiratory tract

A

Acute bronchitis
Acute exacerbations of chronic bronchitis
Pneumonia
Influenza

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3
Q

What is the coryza

A

Common cold
Acute viral infection of the nasal passages
Spread by droplets and fomites
It is self-limiting

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4
Q

What is acute sinusitis?

A

Preceded by a common cold
Purulent nasal discharge
Usually self-limiting, some need antibiotics

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5
Q

What is acute bronchitis?

A

Cold ‘that goes to the chest’
Inflammation of mucus membrane of bronchial tubes
Preceeded by the common cold

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6
Q

What are clinical features of acute bronchitis?

A
Productive cough
May have a fever (minority)
Normal chest examination
Normal CXR
May have a transient wheeze
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7
Q

What is the treatment for acute bronchitis?

A

Usually self-limiting

Antibiotics only given if the patient has underlying lung disease

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8
Q

What are the clinical features of acute exacerbation of chronic bronchitis?

A

Follows upper respiratory tract infection
Worsening of sputum production which is now purulent
More wheezy
Breathless

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9
Q

What would be seen on examination of a patient with an acute exacerbation of chronic bronchitis?

A
Breathless
Wheeze
Coarse crackles
May be cyanosed
In advanced disease - ankle oedema
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10
Q

What management would a patient with an acute exacerbation of chronic bronchitis receive in primary care?

A

Antibiotic e.g. doxycycline or amoxicillin
Bronchodilator inhaler
In some cases, a short course of steroids

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11
Q

What additional management would a patient with an acute exacerbation of chronic bronchitis receive in hospital?

A

Measure arterial blood gases
CXR to check for additional diseases
Give oxygen if there is respiratory failure

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12
Q

What are the symptoms of pneumonia? (15)

A

Malaise, anorexia, sweats, rigors, arthralgia, headaches, confusion, cough, haemoptysis, dyspnoea, preceeding URT, abdominal pain and diarrhoea

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13
Q

What are the signs of pneumonia? (8)

A

Fever, rigors, herpes labialis, tachypnoea, crackles, rub, cyanosis and hypotension

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14
Q

What investigations would be carried out for pneumonia?

A

Blood culture, serology, arterial blood gases, full blood count, urea, liver function and CXR

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15
Q

What is the CURB 65 score for pneumonia?

A
C - new onset of confusion
U - urea >7
R - respiratory rate >30/min
B - blood pressure systolic <61 
65 - age 65 or older 
Score 1 point for each of the above 
Mortality increases as CURB65 increases
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16
Q

What is the most common bacteria to cause pneumonia?

A

Streptococcus pneumoniae (pneumococcus)

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17
Q

What treatment would be given for community acquired pneumonia?

A
Antibiotics - doxycycline or amoxicillin
Oxygen - SaO2 94-98%
Fluids
Bed rest
No smoking
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18
Q

What are 3 special cases of pneumonia?

A

Hospital acquired
Aspiration pneumonia
Legionella

19
Q

What can be done to prevent pneumonia?

A

Influenza and pneumococcal vaccinations

20
Q

Who is entitled to influenza and pneumococcal vaccinations?

A
Over 65yo
Chronic chest or cardiac disease
Diabetes
Immunocompromised 
Health care workers (just influenza)
21
Q

What is the clinical presentation for influenza?

A
Fever - high and abrupt onset
Malaise
Myalgia
Headache
Cough
Prostration (weak)
22
Q

What is the cause of classical ‘flu?

A

Influenza A virus and influenza B virus

23
Q

How is ‘flu transmitted?

A

Droplets or direct contact with respiratory secretions from an infected individual

24
Q

What is an epidemic?

A

A widespread occurrence of an infectious disease in a community at a particular time

25
What is a pandemic?
A multi-continent epidemic
26
What is the therapy for 'flu?
Symptomatic therapy - bed rest, fluids, paracetamol | Antivirals - Oseltamivir and Zanamivir - given uncer NICE guidelines
27
How do labs confirm influenza?
Direct detection of the virus using PCR (virus from swabs of respiratory samples) Or antibody detection
28
What types of vaccine are used to prevent 'flu and who receives them?
Killed vaccine given annually to adults at risk of complications, healthcare workers and children between 6months - 2yrs at risk of complications Or live attenuated vaccine given to children aged 2-17yrs, administered intra-nasally
29
What is mycoplasma pneumoniae a common cause of?
Community acquired pneumonia
30
What is the clinical presentation of bronchiolitis?
``` First or second year of life Fever Coryza Cough Wheeze Severe cases - grunting, decreases PaO2 an intercostal/sternal indrawing ```
31
What are 4 infections of the trachea and bronchi?
Acute epiglottitis Acute exacerbations of COPD Cystic fibrosis Pertussis (whooping cough)
32
What virus causes acute epiglottitis?
Haemophilus influenzae
33
If there is an increase in sputum purulence what treatment would be given for an acute exacerbation of COPD?
1st line - amoxicillin 1g three times a day for 5 days | 2nd line - doxycycline 200mg day 1 then 100mg daily for 4 days
34
What is cystic fibrosis?
Inherited defect | Leads to abnormally viscid mucus which blocks tubular structures in many different organs, including the lungs
35
What is the clinical presentation of pertussus?
Acute tracheobronchitis Cold like symptoms for 2 weeks Paroxysmal coughing Residual cough for month or more
36
Name 6 infections of the lungs
``` Community acquired pneumonia Nosocomial pnuemonia (aka hospital acquired) Legionnaires disease Pneumocysitis carinii pneumonia (PCP) Fungal chest injection Tuberculosis ```
37
What percentage of community acquired pneumonia is accounted for by 'atypical' bacteria?
20%
38
Amoxicillin does not cover the atypical bacteria. What antibiotic is given to cover the atypicals?
Clarithromythen
39
What are 5 predisposing factors to nosocomial pneumonia?
``` Intubation Intensive Care Unit Antibiotics Immunosuppression Surgery ```
40
Are the majority of nosocomial pneumonia caused be gram positive or negative bacteria?
Gram negative
41
What is legionnaires disease?
Flu like illness May progress to severe pneumonia, with mental confusion, acute renal failure and GI symptoms Associated with travel and usually water
42
What is a cause of pneumonia in patients with AIDS
Pneumocysitis carinii pneumonia (PCP)
43
What causes TB?
Mycobacterium tuberculosis
44
What are the causative organisms in community acquired pneumonia?
``` Streptococcus pneumonia (70%) Atypicals/viruses (20%) Staphylococcus aureus (4%) Other bacteria (1%) Haemophilus influenzae (5%) ```