Resting Cell Membrane Flashcards
(31 cards)
What is the resting membrane potential?
The resting membrane potential is the difference in electric charge across the cell membrane when the cell is not actively sending signals.
True or False: The resting membrane potential is typically negative.
True
What is the typical value of resting membrane potential in neurons?
-70 mV
Fill in the blank: The resting membrane potential is primarily determined by the distribution of ______ across the cell membrane.
ions
Which ion has the highest permeability at rest?
Potassium (K+)
What role do sodium-potassium pumps play in maintaining resting membrane potential?
They help maintain the concentration gradients of Na+ and K+ across the membrane.
True or False: At resting membrane potential, the inside of the cell is more positively charged than the outside.
False
What are the main ions involved in establishing resting membrane potential?
Sodium (Na+), Potassium (K+), Chloride (Cl-)
Multiple choice: Which of the following ions is more concentrated inside the cell at resting potential? A) Na+ B) K+ C) Cl- D) Ca2+
B) K+
What is the Nernst equation used for?
To calculate the equilibrium potential for a specific ion.
Fill in the blank: The Goldman equation accounts for the permeability of ______ to calculate membrane potential.
multiple ions
True or False: Resting membrane potential can change in response to external stimuli.
True
What is hyperpolarization?
An increase in the membrane potential, making the inside of the cell more negative.
What is depolarization?
A decrease in the membrane potential, making the inside of the cell less negative or more positive.
Which channel is primarily responsible for the influx of sodium ions during depolarization?
Voltage-gated sodium channels
Multiple choice: Which of the following factors does NOT affect resting membrane potential? A) Ion concentrations B) Membrane permeability C) Temperature D) Cell size
D) Cell size
What happens to the resting membrane potential if potassium permeability increases?
The resting membrane potential becomes more negative (hyperpolarizes).
Fill in the blank: The term ‘polarized’ refers to the ______ of the cell membrane at rest.
charge difference
What is the significance of the resting membrane potential in neurons?
It sets the stage for action potentials and signal transmission.
True or False: The resting membrane potential is the same in all cell types.
False
What is the primary reason for the negative charge inside a resting cell?
The higher concentration of negatively charged proteins and other anions inside the cell.
What does the term ‘electrochemical gradient’ refer to?
The combined effect of the concentration gradient and the electrical gradient for an ion.
Multiple choice: Which of the following contributes to the resting membrane potential? A) Active transport B) Passive diffusion C) Both A and B D) None of the above
C) Both A and B
What is the effect of a drug that inhibits sodium-potassium pumps on resting membrane potential?
It would disrupt the maintenance of resting membrane potential, leading to depolarization.
