Resus Flashcards

(80 cards)

1
Q

What is CVP waveform

A

CVP is the measured pressure in Right Atrium- represent right sided filling.
a=atrial contraction
c=closure tricuspid valve
X=atrial relaxation
V=passive filling atrium
y= open tricuspid valve
Normal =5-12cm <5 hypovol >12 RVF
Analysis
Dominant a wave- TS/PS or pulm HTN
Dominant V wave- TR
Absent x descent- cardiac tamponade
Increased CVP- RvF - PE/ tamponade/ TV incompetence.

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2
Q

What is atrial waveform

A

1- systolic upstroke ventricular ejection - increased slope =increased contractility
2- systolic decline - rapid decline atrial pressure when ventricle stop contracting
3- diacritic notch- closure aortic valve pressure- measured at aorta
4- diastolic delay- pressure decrease as ventricle stops contracting

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3
Q

What is targeted temp management

A

Target <37.5
Principle- thought to improve outcomes AlS to protect against cerebral oedema
Avoid hypothermia
Duration 24 hrs
Prevent fever
No good evidence to actively cool
Not pre hospital

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4
Q

Causes PEA arrest

A

B-road complex QRS- us- LV hypokinesis- if hyper K- ca gluconate 10%60ml cacl-10%30ml
Na channel blocker- sodibic 100ml 8.4%
Or
Narrow complex QRS- RV collapse or tampon are or PTx pneumothorax
RV full- PE

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5
Q

Indications stopping CPR

A

Injuries not compatible with life-100% TBSA burn
NFR order
k>12 ph <6.5
No sign life Temp >32 degrees or 2hrs CPR <15 degrees
20-30 mins CPR- no ROSC (if rosc restart timer)
Underlying Rhythm- PEA or Asystole
Traumatic arrest- give blood
Or newborn- no HR after 10min CPR

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6
Q

HYPOTHERMIA - CPR

A

Reward pt- passive- remove wet clothes/dry/blanket
Active-external 28-32 degrees bair hugger
-internal- severe + CPR- thoracic/abdo lavage. Haemofiltratiin
<20 deg- intermittent CPR 5 min on 10 min off
<28 deg intermittent CPR 5 min on 5 min off
<30 no drugs trial 3 stacked shocks (defib not good till > 30 deg)
30-34 deg- double normal AlS drug intervals
Prolonged CPR till at least 30 degrees
Greater survival if rapid onset hypothermia
Child accidental etoh or drugs

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7
Q

CPR with toxins

A

CO- supplemental O2
Lignocaine Tox- intralipid- 20% 1-5mg/kg bolus
Cyanide- hydroxycobalamin 5mg IV
Digoxin- digibind in CPR 20 amps
TCA- sodibic 2mmol/kg 2-3 min post rosc
Opioids- Bali one 100mcg pre arrest IV 30-60 sec

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8
Q

CPR in pregnancy

A

Get help- OBGYN peads
L- lateral position
IV mgSO4- 4g Eclampsia
Causes- Cardiac/ PE/ haemorrhage-txt MTP
Sepsis/ ivabx/ IVF/ inotropes
HTN- eclampsia HELLP
Toxins
Amniotic fluid embolism
Prepare perimortem ceaser

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9
Q

CPR- in Trauma

A

Compression not routine
1-stop bleed
2-airway ETT
3- decompress chest- 2 finger thoracotomy
4- open chest decompresspercarditis
5- plug ventricular lacs
6- compress aorta
7- twist hi Lyn
8- MTP
9- crush injury manage hyper K

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10
Q

CPR and pulmonary Embolism

A

If lysis- ateplase <60kh 10mg bolus and 1.5mg/kg 2-4 hrs
Ateplase- >60mg 10mg IV bolus 90mg 2 hours
Heparin infusion
Prolonged CPR- 2 hrs post thrombopysis

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11
Q

CPR and asthma

A

Disconnect - BVM cpr forced exp
Seek and treat PTX
Prolong CPR and IVF
Severe bronchospasm/ mucus plug- CPR can dislodge and early tube suction and take over ventilation
Bronchodilators if ROSC

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12
Q

Anaphylaxis - CPR

A

Adrenaline- IM 500mcg IV- push 1mg +++
Prolonged CPR
Urgent intubation - vent
Fluid 20ml/kg
Adrenaline adrenaline Aim Map>65

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13
Q

ALS drugs dose and indication

A

Sodibic- 1mmol/kg 2-3 mins indicated hyper K TCA OD or metabolic acidosis
Calcium- cacl- 10% 5-10ml 3x more Ca or ca gluconate- 15-30ml 10%- indicated ca channel OD/ high K and low Ca
Mag- 5-10months bolus 20ml 4 hr infusion or mg torsades- hypo K low mg and dig toxicity
Potassium- 10-40 mail k<2.5

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14
Q

ALS drug- lignocaine dose/ indication

A

Anti arrhythmic- class 1b
Dose- 1-1.5 mg/kg after 10 mins 0.5 mg/kg
Indicated- refractory VF or pulseless VT or VT storm
Adverse effect- hypotension/ bradycardia and heart block/ asystole or CNS toxicity

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15
Q

Resus drugs- ALS - Amiodarone dose/MOA or induction

A

Dose- arrest 300mg bolus with further 150mg IV if req
Indication- refactory or pulseless VF/VT - 3rd loop/ shock
Class 3 anti arrhythmic
Adverse effects- hypotension/ bradycardia/ heart block/ prolonged QT

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16
Q

ALS drugs- Adrenaline- dose/routes/ MOA

A

ALS- 1mg every 2nd Loop -VT/VF 2nd shock
- PEA/asystole- after 1st rhythm check
Stridor- nebulised 1mg in 10ml
IV/IO- cpr 10mcg/kg or pressor 10mcg
ACEM- 5mcg/min titrate up or down
Adverse effect- tachycardia/ severe HTN with ROSC
Tissue necrosis if extravate
MOA- alpha/ beta receptors - inotrope/ chronotrope raised SVR. Increased cerebral and coronary blood flow
Decreased splanchnic and peripheral
Tachycardia

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17
Q

What are the steps post ROCS

A

A- ETT/ LMA secure airway- NGT/ CXr
B- aim SaO2 >94% max rib # or PTx and lung protective vent
C- target- SBO>100 MAp>80 12 lead ECG - cath lab if ischarmia
Inotrop- adrenaline 6mg in 100ml5-20 ml/hr amiodarone 0.6mg/kg/ hr
D- cerebral protection- head 30 degrees map>80 normo- glycaemia/ thermia/ normal Na. My seizure
Sedate P and F or M and M
Update Fsmily
ICU- organ donation?
Document and debrief

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18
Q

4Hs and 4Ts management

A

Hypoxia- Fio2-100%
Hypovolemia- ivf 20ml\kg blood TEG
Hypo K- kcl 20min l peripheral 40 mmol CVC
Hyper K- cagluconate 10% 30ml. Insulin/ dextrose 10 units 50ml 50% dextrose and sodibic- 100ml 8.4%
Hypo/ hyperthermia- <35 >40 rewarm or cool.
Tension PTx- finger thoractomy ICC mid axillary line 4 ICS
Toxins- antidote/ charcoal/ dialysis
Tamponade- percardiocentesis/clam shell
Thrombosis/ thrombus- cardiac PCI or PE- thrombolysis

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19
Q

What are causes of polymorphic VT

A

Torsades long QT
AMI
Short QT syndrome
Bi directional VT- dig toxcicity
Catecholamnergic polymorphic VT

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20
Q

Cardiac arrest- when can you use 3 stacked shocks

A

In witnessed monitored arrest where defib attached

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21
Q

What is coached algorithm

A

C- compression continued
O- oxygen away if BVM
All others clear
Charging
Hands off
Evaluate rhythm
Defib or disarm

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22
Q

Cardiac arrest - when can u use precordial thump

A

Witnessed VT-VF arrest with no pulse and no defibrillator on sight

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23
Q

Cardiac arrest- what is the chain of survival

A

Early recognition of CA
Early continuous CPR
Early defib
Minimise interruptions to cx compressiins
Aim nor other is
Avoid hyper or hypo O2

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24
Q

Peadiatric intubation differences

A

Straight blade- anatomy large tongue/ loose teeth short upper airway/ floppy glottis/ soft collapsible and big head
ETT= age/4 + 4 depth ETTx3
Pre oxygenate rapid desat has low FRC
ROC/ fent and Midas
Ketamine 2-4mg/kg
Roc 1.2mg/kg
Ensure IV access or IO
Adrenaline 10mcg/ kg
Famil- consideration and communication

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25
Airway- what changes need to be thought about for intubation obese pt
Buy time- NIV/ delayed SI Indications- do in DEM or OT Get help- ent/ anos Ramp- tragus to eternal notch Aponeic O2- 15L/Min Minimal drugs- ketamine or ROC Pre O2- PEEP/ BVM/ NIV Plan for difficulty Post- intubated care
26
What changes need to be thought about in septic pt intubation
Optimise the pt- pressors or IVF Drug choice- ketamine 0.5mg/kg ROC 1.6mg/kg Reduce induction drug dose Increased muscle relaxant dose Maintain resp comp increased RR
27
Complications when intubating asthmatic patient
Pneumothorax Dynamic hyperinflation Hypotension- decreased venous return and increased auto prep Think- D- dislodged tube O- obstructed tube P- pneumothorax E- quipment failure S- stacking
28
What considerations need to be made in intubating asthmatic
Become hypotensive- give IVF prior DelayedSI- NIV/ BVM/ PEEP Drugs- ketamine 1-2 mg/kg - b agonist and bronchodilator ROC- 1.2 mg/kg IV Larger ETT size to reduce breath stacking ++ bronchodilators prior or post- IV salbutamol or IV adrenaline
29
What are ideal ventilator settings in asthma
Vent- VC and SIMV TV 6ml/kg RR 6-8 Prolonged I:E ratio 1:4 reduce breath stacking
30
What is different when intubate pregnant person
Similar concept difficulties for obese pt Similar size ETT size Intubate- in L lateral posturing wedge right hip Laringoscope short handle Kessel blade
31
Muscle relaxant reversal agents- non depolarising
Neostigmine adult 2.5mg + atropine 1.2mg Child 0.08mg/kg Suggamedex- normal 16mg/kg
32
Muscle relaxants vecuronium dose and duration
Vec- non depolarising 10mg powder dilute 10mg in 10ml saline-1mg/ml Dose 0.1mg/kg adult 10mg Induction- 0.3mg/kg RSI Duration 30 mins
33
Muscle relaxant- Rocuronium dose/ onset/ metabolised/ adverse event
Non depolarising ROC- 50mg in 5ml dilute 10mg/ml Induction 1-1.2 mg/kg adult 100mg Maintence 0.6mg/kg Onset duration 45-60 secs Duration 20-35 mins Metabolised liver Adverse effects- hypersensitivity/ tachycardia/ pain on injection/ if anticonvulsant- increased dose ROSC
34
Suxamethonium- cI and side effects
Depolarising CI- congenital myopathy Neurology condition in last 6 months Burns to 20% TBSA Infection Hyper K and Hypo k Adverse K- hyper K in burn pt Muscle fasiculations Bradycardia esp in child Decreased LOS tone- GORD/asp Malignant hypothermia Aponea Increased intraoccular pressure
35
Suxamethonium- dose/ phases/ duration/ onset
Presentation 100mg in 2ml as 50mg/ml Dose- 1.5mg-2mg/kg adult 1-2.5 ml adult 100-150mg Duration- 10mins Rapid onset- fasicukations 30secs relax 45-60sec 2 phases 1- depolarising fasiculations flaccid paralysis 2- de- sensitising membrane desensitised early depolarised again
36
Head injury- what do need to consider intubating pt
Minimise changed in BP- reduced induction dose- ketamine 1mgkg fentanyl 2-3mcg/kg ROC 1.2mg/kg Anticipate difficult if collar- inline stabilisation or BURP Neuroprotective- head 30 degrees/ neck clear/ saO2 >90 PCO2 35-45 MAP>80 normothermia/ normoglycaemia Na 135-145
37
Suxamethonium order of sensitivity of neuromuscular blockade
Large limbs—> diaphragm —> small trunk —> Larangeal—> eye muscles
38
Surgical airway approach
Steps 1- stabilise thyroid cartridge 2- palpate cricoid membrane 3- 4cm vertical incision into CTM 4- wide horizontal incision CTM 5- dilate finger- confirm location 6- bougie—> size 6 ETT 7- connect and confirm
39
Target for management of shock
SVR 800-100 MAP >65 C.O- 4-8L/min HR 60-100 SV 60-100ml per beat SBP 100-140 mmHg DBP 60-90 mmHg
40
Management of hypovolaemia
Stop fluid losses IVF 20ml/kg 0.9% Haemorrhage- stop/ blood/ OT Vasopressors NA- 5mcg/kg/min or 5ml/hr titrate Metaraminol 0.5mg blouses infusion 5-10mcg/hr Dopamine 1-5mcg/hr Inotropes Adrenaline 10mcg bolus 5ml/hr or 5mcg/min/hr- titrate Isoprenaline 5mcg/hr Dobutamine no peripheral effect-1-40mcg/hr titrate Adrenal insufficiency- hydrocortisone 200mg
41
Classification of hypovolaemia
Class 1- normal vitals/ <15% loss Class 2- tachycardia 15-30% loss Class 3- hypotension 30-30% loss Class 4- ALOC > 40% losses (>2L) Volume assess- US- IVC collapse Pulse pressure CVP changes Passive leg raise- like giving 300ml bolus
42
Hypovolaemia shock
Reduced SV or reduced CO Intravascular losses- Blood losses - external= trauma - Internal= Haemothorax/ Haemoperitoneium/ retroperitoneal and pelvis Plasma losses - burns/ sweat or dehydration/ pancreatitis/ ascites/ peritonitis/ liver disease/ erythroderma/ phemphihoid Extravascular GIT- D and Vs or bowel obstruction Renal- Adrenal insufficiency/ DM Diabetes insipidus Diuretics Polymeric intrinsic renal disease
43
What is cardiogenic shock
Myocardial inability to supply adequate O2 for tissue perfusion 1- reduced contractility- SV low - AMI - myocarditis - myocardial contusion - cardiomyopathy - etoh/ infection - Toxin- B blocker or Ca ch blocker 2. Inadequate filling- diastolic dysfunction I. E Right ventricular infarct 3. Arrhythmia - AF/VT/ Bradycardia 4. failure forward flow- LVOT obstruction-HOCM/ Ruptured free walk or papillary muscle Stenosis AS or MS Thrombus
44
How to assess fluid responsiveness
1. Clinical end pt- HR/ BP/CRT/ U.O/ CVP/ lactate 2. Dynamic tests - passive leg raise assess BP or pulse pressure on artline Advantage- repeatable and non invasive Disadvantage- not reliable severe hypovol 3- US assess SV on echo Lung- b lines signs of APO iVC collapsible
45
Management of cardiogenic shock
AMI- PCI or thrombolysis NSTEMI - aspirin300mg ticagrelor 180mg load/ heparin 5000IU/ O2 Analgesia- fentanyl 25mcg +\- NA/ adrenaline or dopamine Dobutamine - 1st inotrope choice in cardiogenic shock Non meds Insta aortic balloon pump ECMO for reversible causes of cardiogenic shock
46
What is distributive shock
Shock secondary to altered venous capacitance or tone - anaphylaxis/ neurogenic/ septic shock - adrenal insufficiency - thyrotoxicosis - liver failure - SIRS- burns/ pancreatitis Things that decrease SVR Mx- IVF Adrenaline- anaphylaxis NA others
47
What is spinal shock
Spinal shock refers to temporary loss of all neuroglogic activity below level of injury - motor/ sensory and autonomic - paralysis/ loss sensation - does not cause hypotension or bradycardia
48
What is neurogenic shock
Altered venous capcitence +\- vascular tone Secondary to autonomic dysfunction caused by spinal injury above level of T6 Characterised by- Flaccid paralysis/ hypotension and bradycardia Urinary retention- below the level and resp compromise c3/4/5
49
What is shock and what targets do we monitor
Shock= a state of circulatory failure resulting in inadequate perfusion and oxygenation. Targets MAP- 65mmHg HR <100 SBP >90 Caprefill <4 seconds CVP>10 U.O >0.5 ml/kg/hr adult or >1-2 ml/kg/hr peads Lactate <2
50
Which bloods correlate on IO or venous blood
Good correlation VBG/ glucose/ urea/ CRT/ Hb/ Hct/ albumin and chloride Bad correlation WCC/ PLTS/ Na/ K/ Ca/ venous O2
51
Complications of IO
Extravasation Infection- OM Fracture Necrosis of bone Compartment syndrome Failure Injury surrounding structure- vessel/ nerve Damage in child to ephyseal growth plate
52
Sites for Interosseous line
Proximal Tibia- @ tibial tuberosity 1-2cm medial and 1-2 cm down Proximal humerus- @ greater tubercle with adducted shoulder Distal femur - anterolateral surface 3cm above lateral console Distal Tibia - 2cm above medial malleolus
53
Contraindications IO
Overlying infection to site Bone fracture at site- risk compartment syndrome Bone disorder I.e osteogenesis imperfecta Ipsilateral vascular injury
54
Neonatal- decisions to withdraw care
CPR + vent > 10mins of effective ALS with no ROSC Individual case decision/ team decision DO NOT initiate Resus gestation <23/40 or BW <400g as 1% chance of survival Or if anencephaly or trisomy 13 or 18
55
Causes for unwell neonate
Trauma- accident or NAI- hx/exam odd story Heart disease- cyanosis/ pre and post distal sats/ sob/sweaty/ murmur/ FTT Endocrine or electrolytes- CAH ambiguous genital high K and low Na. Txt 25mg hydrocortisone Metabolic - BSL high or low. Inborn error of metabolism- urea cycle- raised ammonia. Organic acids- hAGMA Sepsis- TORCH infections/ dex- 0.15mg/kg cefoaxaime 50mg/kg ampicillin 50mg/kg and aciclovir 10mg/kg Formula or feeding- too strong or too weak- BSL- hyper/hypo Na Intestinal catastrophe- intussception/ pyloric stenosis/ NEC or Hirshsprungs Toxin- nai opiate/ TCA Seizure or CNS abnormalities - midaz / phenobarbitone 20mg/kg or Keppra 20-60mg/kg
56
TORCH infections in neonates
Toxoplasmosis Other - syphilus/ parvovirus Rubella CMV Herpes/ HIV
57
Management of unwell neonate
1- get help- PICU/ Peads 2- warm/ stimulate/ 360 degree access/ ABCD and APGAR 3- A + B- head neutral- neopuff/ t piece - PPV 30cm H2O and Fio2 21% but HR <60 Fio2 100% persistent tachyponea intubate 4- c- 1-2 IV attempts IO or scalp/ umbilical access- bloods/ vbg/ culture and BSL- metabolic and hypoglycaemic screen and ammonia level IVF 0.9% nacl 10-20mg/kg rpt 10mg/kg if needed. DEFG- 5ml/kg 10% dextrose if BSL< 2.8 maintenance at 5mg/kg/min Seizure- midaz 0.1mg/kg Phenobarbital 10-20mg/kg
58
What is APGAR score
Baby born start APGAR taken at 1min/5 min and 10 mins 0 1 2 Appearance Blue/pale bluish. Pink Pulse rate. Absent. <100. >100 Grimace Absent. Yes. cough Activity. Limp. Flex. Active RR Absent. Irreg. cry
59
Neonatal post CPR/ Resus cares
1- secure airway- ETT 2- maintain vent pao2 60-90 PCO2 35-40 mmHg 3- secure IV avoid hypotension 4- close monitor- SCN or PICU ? Sedation 5- seek complications of end organ injury 6- communicate/ debris and family counsel
60
61
Compare restrictive and lung protective ventilation
Protective SIMV 6-8ml\kg RR- 16-18 Pmax <40 cmH2O Plateau pressure- <30 FiO2- 88-95% I:E 1:1.5 Restrictive asthma/copd SIMV 4-6ml/kg RR6-8 Pmax <45 Plateau pressure <30 fIO2 88-95% I:E 1:4 or 1:5 Sedation and paralysis Permissive hypercapneia if PH>7.1
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63
Indications and contraindications for NIV
Indications- bipap mx increase airway resistance cpap- all else Awake and point breathing pt Co operative Free of excess secretions Increased WOB T1RF- hypoxia- apo/ post extubation stridor/ hypoxia pneumonia T2RF- copd/ asthma- high CO2- tired pt- neuromuscular weak- M.gravis/ dmd/SMA/ upper spinal cord injury Contraindications Claustrophobia Uncooperative ALOC Obtunded Facial anomalies or trauma Vomiting Haemoptysis or haematemsis Airway- can’t protect - no gag/ ++ secretions Note may cause increased intrathoracic pressure
64
Complications of NIV
A- airway/-aspiration/ aweophagos- delay to definitive tube B barotruma or PTx C hypotension due increased intrathoracic pressure D- disability- raised ICP/ not tolerating E- excess O2 G gastric insufflation Aspiration- vomit Epistaxis Facial skin necrosis
65
66
Explain difference between Bipap and Cpap
Bipap- IPAP (insp pressure =Peep+PS and EPAP- PEEP IPAP start 8-10 and PEEP 5cm H20 COPD/ASTHMA and APO CPAP- continuous fixed amount positive end exp pressure though entire vent cycle usually 5-10cmH20 Aim to increase alveolar vent- splint end bronchioles. Reverse hypercap Increase alveolar recruitment and decrease work of breathing and reduced LV after load increase CO Caveat- can increase intrathoracic pressures and reduce preload to heart
67
ARDS ventilator settings
Aim to reduced volumes and barotrsums and biotrauma Lung protective ventilation Berlin definition- ARDS - acute onset <1/52 - bilateral opacities and infiltrates consistent APO - no evidence of HF or overload Low PaO2:FiO2 ratio <200mmHg Mode- pressure controlled - pmax 30cmH2O - plateau pressures 30 FiO2- keep SaO2 >90 Tv 6ml\kg PEEP start 5cm and titrate up I:E 1:2 Permissive hypercap
68
ABCs of APLS
A- adjuncts npa= tip of nose to tragus Neonate in neutral position Child- neck flex and head extended Head tilt/ chin lift/ BVM- may cause resistance in point breathing child Neopuff in neonate T- piece- up 20kg child - low resistance and assist with TV no valve apply PEEP fingers Tube- ETT uncuffed age/4 +4 B- 15:2 with 2 rescue breaths to start and neonates 3:1 C- umbilical access/ scalp acces and IO D defib at 4J/kg
69
ABC neonatal Resus
A- assess gasps/ aponea give PPV- neopuff or BVM or T Piece Rate 40-60 On FiO2 21% Pressure max 30 cmH2O HR<60- start compressions and FiO2 100% B- saO2 on pre ductal side right arm C- HR < 100 ass airway and start PPV if HR<60 ratio 3:1 rate 100 FiO2 100% Adrenaline 10mcgkg every 3-5 mins Glucose 5ml/kg of 10% dextrose
70
APLS drug doses
Lignocaine- 1mg/kg IV/IO Adrenaline 10mcg/kg IV/IO- non shockable immediate with VT or VF after 2nd shock Amiodarone- 5mg/kg IV/IO - 3rd shock or non shockable immediate Glucose- 5ml/kg 10% dextrose Mag- 0.1-0.2 mmol/kg- torsades NaHC03- 1-2mmol/kg metabolic acidosis Calcium gluconate 0.7mg/kg and calcium chloride 0.2mg/kg Atropine 20mcg/kg Naloxone 0.1mg/kg
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What is shock
Mitochondria 1st effected - 2 to decreased tissue perfusion and reduced O2 delivery Results in decreased perfusion to vital organs Increased alveolar vent Reduced base excess more neg
73
5 causes of shock
1 hypovolaemic - trauma/ haemhorsggic - GIT losses/ dehydration - 3rd spacing- burns 2- Cardiogenic - STEMI/ ACS Myocarditis Arrhythmia Septal wall rupture Cardiomyopathy B/ Ca ch overdose CHF 3- obstructive- physical obstruction limits CO - PE/ tension PTX/ cardiac effusion/ tamponade/ severe AS or MR/ PDA closure/ HOC. Or air or amniotic embolism 4- distributive shock - septic shock - anaphylaxis - neurogenic - burns - drug OD - adrenal crisis 5- cellular toxin induced - CO - cyanide - methaemoglobinaemia - hydrogen sulphide
74
Vitality of base excess and lactate in management of shock
Marker of shock- BPlow/ RR high/ Tachycardia Lactate and BE- BE is the metabolic component of acid/ base status +2 to -2 How much HCO3 used up More acidosis higher neg base - eg -6 is very sick Lactate is by product secondary to tissue hypoxia but can also be due to non hypoxia lactate >4 very sick
75
Define SIRS
Systemic inflammatory response syndrome- Temperature <36 or >38.3 HR>90 RR>20 CO2 <32 WBC <4000 or > 12000
76
Define sepsis and severe sepsis
Sepsis- SIRS with suspected source of infection Severe sepsis- sepsis + organ dysfunction raised lactate/ raised CRT/ decreased UP deranged LFTs
77
Define septic shock
Severe sepsis plus tissue hypoperfusion despite an adequate fluid challenge
78
5 criteria of circulatory shock
Need 4-6 1- I’ll appearance or ALOC 2- HR>100 3- RR>20 PaCO2 <32 4- BE >-4 or lactate >4 5 U.O < 0.5ml/kg/hr 6 arterial hypotension constant > 30 mins
79
Early goal directed therapy in shock
Try to achieve in first 6 hrs - map >65 - u.O > 0.5ml/kg/hr - CVP > 8-12 - central Venus O2 > 70mmHg or mixed venous O2 >65 maggots Normalise lactate
80
Management of cardiogenic shock
1- minimise myocardial O2 demand- ie take away WOB and intubate 2 maximise cardiac output - fill tank IVF 250ml map >65 - stimulate the heart- dobutamine 0-5 mcg/kg/min start at 2.5 mcg/kg/min and nitrate - add peripheral squeeze- preload- NA 5mcg/kg/min and titrate - reduced O2 req- do we need to I and V pt and take over do they have WOB - disposition- Cathlab? iCU? Ecmo? CCU ?