Reversal of Warfarin/Coumadin - Blood Products

Question 1

Is Prothrombin Complex Concentrate (PCC) a blood product

Answer 1

Yes, and requires consent & paperwork

Question 2

What is the most common Prothrombin Comples Concentrate (PCC)?

Answer 2

Octaplex is most common, Beriplex less so

Question 3

When should IV Vitamin K be administered for reversal of Warfarin/Coumadin?

Answer 3

Must be administered either before or during PCC infusion

Question 4

What is the dose of Vitamin K in reversal of Warfarin/Coumadin?

Answer 4

10mg IV via slow infusion ( <1 mg/min)

Question 5

What is Octaplex (PCC) dosing based on?

Answer 5

INR & weight