Reversing Warfarin

Question 1

Major bleeding

Answer 1

Stop warfarin
PCC

Question 2

INR>8 minor bleeding

Answer 2

Stop warfarin
IV VIT K 1-3mg
Repeat after 24 hrs if needed
Restart when INR <5

Question 3

INR>8 no bleeding

Answer 3

Stop warfarin
Give oral vit K 1-5mg
Repeat if needed after 24 hrs and restart when INR <5

Question 4

INR 5-8 minor bleeding

Answer 4

Stop warfarin give IV vit K 1-3mg and restart when INR<5

Question 5

INR 5-8 no bleeding

Answer 5

Withold 1-2 doses and reduce subsequent dose