REVIEW Flashcards
(14 cards)
Intensity and duration dependent substrate utilization – how is this regulated
Reciprocal regulation of substrate utilization
Hormonal and allosteric regulation of glycolysis enzymes
Rate limiting enzymes
RER (know the RQ/RER for lipid 0.7 and CHO 1.0, CO2/O2 (production/consumption))
Lactate threshold
Cori and glucose-alanine cycles
Energy regulation/ substrate utilization and choice
Enzymes/receptors/translocators – hexokinase, pyruvate dehydrogenase, lactate dehydrogenase, PFK, pyruvate kinase, AMPK, GLUT4, phosphorylase, hormone sensitive lipase, CD36/FAT
Key signals – hormones – catecholamines (epinephrine), insulin, glucagon
Metabolites (metabolic by-products– ATP, ADP, AMP, Pi, lactate, alanine)
How does epi increase/mobilize fuel sources? HSL
–> adipocytes –> TG –> FA and glycerol to the plasma –> to the muscle
Epi –> liver and muscle to mobilize glycogen