Review Flashcards

(21 cards)

1
Q

Most of the HCO3 reabsorption that represents renal compensation for acid/base disturbances occurs at which portion of the nephron?
- Proximal tubule
- Distal tubule
- Loop of Henle
- Bowman’s capsule
- Collecting tubule

A

Proximal tubule

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2
Q

A strict no-carb high protein diet might on rare occasions cause a metabolic disorder in the acid/base balance. This is due to the overproduction of keto acids from protein digestion. This causes?

Question 28 options:

A base deficit from lowering [HCO3-]

A change in the non-bicarbonate buffering levels

A decrease in PCO2 from an increase in bicarbonate

A reduction on blood buffering ability by hemoglobin

A

A base deficit from lowering [HCO3-]

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3
Q

The advantage that the Siggard-Andersen Alignment Nomogram has over the Davenport Diagram is that…

Question 27 options:

It allows hemoglobin concentrations to be determined

It better determines the difference between acute and chronic imbalances

It better determines the difference between metabolic and respiratory imbalances

Base excess/deficiency can be quantified

A

Base excess/deficiency can be quantified

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4
Q

The following questions deal with an individual diagnosed with diabetes mellitus. The patient would show levels of blood glucose

Question 25 options:

High

Low

Unchanged

A

High

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5
Q

The diagonal line on the Davenport Diagram which is used to show the relationship of pH, [HCO3-] and PCO2 represents?

Question 24 options:

The buffering value of hemoglobin and blood plasma proteins

The ability of the lungs to remove/retain CO2 in the body to balance acid/base levels

The ability of the kidneys to excrete acid to compensate for acid imbalances

The buffering value of bicarbonate

A

The buffering value of bicarbonate

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6
Q

The following questions deal with an individual diagnosed with diabetes mellitus.

What sort of acid base disturbance would also be seen with this individual?

Question 21 options:

Respiratory acidosis

Metabolic acidosis

Metabolic alkalosis

Respiratory alkalosis

A

Metabolic acidosis

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7
Q

In an individual diagnosed with diabetes mellitus, excretion of phosphate would

Question 20 options:

remain unchanged.

decrease.

increase.

A

increase.

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8
Q

What is the “Chloride Ion Shift”?

Question 19 options:

Movement of Cl- out of the blood stream by the kidneys

The addition or removal of a proton from a Cl- ion

exchange of Cl- for bicarbonate across the membrane of a red blood cell

Increased (or decreased) capacity for the blood to buffer Cl-

A

exchange of Cl- for bicarbonate across the membrane of a red blood cell

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9
Q

When CO2 is produced from cellular metabolism it combines with water within red blood cells forming bicarbonate in the presence of what enzyme?

Question 18 options:

carbonyl dehydrogenase

Carbonic anhydrase

Co-A synthetase

Imidizole carbonic transferase

A

Carbonic anhydrase

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10
Q

The extent of bicarbonate formation in the blood depends primarily on the

Question 17 options:

temperature

solubility of bicarbonate in the plasma

type of bicarbonate being formed

solubility of carbonic acid

blood buffers

A

blood buffers

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11
Q

Which condition occurs when there is decreased PCO2, increased pH, and decreased bicarbonate.

Question 15 options:

Acute respiratory alkalosis

Metabolic Alkalosis

Acute respiratory acidosis

No evidence of acidosis or alkalosis

Metabolic acidosis

A

Metabolic acidosis

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12
Q

If a person stops breathing and CPR (mouth to mouth) is preformed for an extended time cardiac arrest might result from what complication?

Question 13 options:

Chronic metabolic acidosis

Acute respiratory alkalosis

Acute respiratory acidosis

Chronic metabolic alkalosis

A

Acute respiratory alkalosis

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13
Q

Which of the following occur as a result of hyperventilation?

Question 12 options:

Reduced PCO2

Lowering pH

Raising HCO3-

All of the above

A

Reduced PCO2

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14
Q
A
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15
Q

You are a physician and you see a very young patient that is urinating in excess. Testing the child’s urine and blood shows elevated levels of monobasic phosphate and ammonium excretion in the urine and a low level of plasma bicarbonate. The blood pH is 7.35. You also notice that the patient breaths fast even when sitting still. This increase in breathing is due to?

Question 9 options:

Compensation for metabolic acidosis

Chronic metabolic alkalosis

Hyperventilation causing respiratory acidosis

Respiratory alkalosis

A

Compensation for metabolic acidosis

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16
Q

In an individual diagnosed with diabetes mellitus, excretion of bicarbonate would

Question 8 options:

remain unchanged.

increase.

decrease.

17
Q

Acidification of the blood will cause what change to the affinity of oxygen binding to hemoglobin?

Question 7 options:

It will reduce the hemoglobin present in the blood

It will decrease oxygen-hemoglobin binding

It will lead to respiratory acidosis

It will not allow for metabolic compensation

None of the above

A

It will decrease oxygen-hemoglobin binding

18
Q

Which of the following locations contain chemoreceptors sensitive to changes in plasma H+?

Question 6 options:

hypothalamus

mammillary bodies

none of the above

medulla

carotid bodies

A

carotid bodies

19
Q

In an individual with diabetes mellitus, excretion of ammonium would

Question 4 options:

increase.

decrease.

remain unchanged.

20
Q

Chemoreceptors that sense [H+] are found ______________ and chemoreceptors for PCO2 are found _______________.

Question 3 options:

heart, lungs

brain, heart

heart, brain

brain, lungs

21
Q

You are a physician and you see a very young patient that is urinating in excess. Testing the child’s urine and blood shows elevated levels of monobasic phosphate and ammonium excretion in the urine and a low level of plasma bicarbonate. The blood pH is 7.35. What is causing the increase acidity of the blood?

Question 1 options:

Acute Respiratory Acidosis

Hypoventilation

Overproduction of organic acids

Compensation for metabolic alkalosis

A

Overproduction of organic acids