Review ch23 Flashcards

(36 cards)

1
Q

Process of digestion

A

ingestion, propulsion, mechanical breakdown, digestion, absorption, defecation

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2
Q

What is segmentation?

A

a part of mechanical breakdown in the small intestine. contractions and mixing of juices and food to help absorb

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3
Q

What is mesentery? what are its 3 functions?

A

double layer of peritoneum fused back to back. extends from the body wall to the digestive organs
F: store fat, hold organs in place, provide routes for BV, Lymphatics, nerves

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4
Q

What organs are in the retroperitoneum?

A

pancreas, duodenum, large intestine

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5
Q

Peristalsis is part of which process?

A

propulsion

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6
Q

4 basic layers of the alimentary canal

A

mucosa, submucosa, muscularis externa, serosa

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7
Q

What are the 3 sublayers of the mucosa? Explain all 3

A
  • epithelium- simple columnar EXCEPT in esophagus, mouth, anus - stratified squamous and mucus-secreting (enzyme secreting)
  • lamina propria- loose areolar c.t. - rich supply of capillaries for nourishment and absorption. Has MALT
  • muscularis mucosae- smooth muscle, produces local mvmts to enhance secretion/absorption
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8
Q

What is the submucosa layer made of? Function?

A
  • aerolar connective.t
  • has lymphoid follicles, nerve fibers, rich blood supply.
  • lots of elastic fibers allow it to change shape and regain normal shape (Stomach)
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9
Q

Which layer is responsible for peristalsis and segementation?

A

muscularis externa

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10
Q

Muscularis externa has inner layer and outer layer explain both (also forms sphincters)

A
inner= circular 
outer = longitudinal
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11
Q

How is the serosa membrane (visceral peritoneum) formed?

A

from areolar connective.t with mesothelium - which is a single layer of squamous ep cells

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12
Q

The esophagus has a dense connective tissue layer - instead of the serosa - what is this layer called?

A

Adventitia

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13
Q

T or F

Reteroperitoneal organs have both adventitia and serosa?

A

TRUE

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14
Q

The enteric nervous system has 2 plexuses, name and explain

A

Submucosal nerve plexus- regulates glands and is in the submucosa
Myenteric nerve.p- in muscularis mucosae - control GI motility

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15
Q

What are the 3 key concepts in the regulation of digestive activities?

A
  1. digestive activity is triggered by many mechanical and chemical stimuli - certain foods that change pH, osmolarity, stretch
  2. effectors of digestive activity are smooth muscle and glands
  3. neurons (intrinsic/ex) and hormones control digestive activity
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16
Q

Salivary glands secrete 2 types of cells - mucous and serous- what do these cells produce?

A

Mucous- mucus

Serous- watery secretion that has enzymes , ions and some mucin

17
Q

Salivary glands have what types of enzymes?

A

amylase, lingual lipase (fat)

18
Q

What 3 protective factors of saliva?

A
  1. Defensins - act as local antibiotics, function as cytokines to call other defensive cells
  2. lysozyme- the bacterial enzyme that inhibits bacteria growth. can help with tooth decay
  3. IgA antibodies
19
Q

What is the muscularis externa made of in the esophagus?

A

Superior is skeletal muscle and inferior is smooth muscle

20
Q

what part of the pharynx allows for food to move down?

A

contractions of the pharyngeal constrictor muscles - Longitudinal layer

21
Q

main function of esophagus and pharynx?

A

Propulsion of food

22
Q

Swallowing (deglutition) has 2 phases explain

A
  1. Buccal phase- in mouth and is voluntary

2. pharyngeal-esophagus - involuntary, involves vagus nerve

23
Q

Which part starts the chemical breakdown of proteins? How?

A

Stomach - parital cells secrete HCL which converts pepsionogen to pepsin (active enzyme)

24
Q

Longitudinal folds in stomach, stores mucosa

25
Which part of the stomach allows for more churning and break down of food?
innermost layer- oblique layer
26
mucosa of the stomach has a 2 layer coat coat consisting of what?
alkaline mucus and the top layer has insoluble mucus that traps a layer of bicarbonate rich fluid under it
27
The mucosa of stomac is lined with gastric pits which lead to gastric glands where gastric juice is made - name the 4 types of gastric gland cells from top down and their functions
mucosa neck cells- think soluble acidic mucus parietal cells- secrete HCl and intrinsic factor Cheif cells- mainly in basal region, produce pepsiongen (inactive) Enteroendocrine cells - realse chemical messangers such as histamine and serotinin (paracrines) and somatostasin, and the hormone gastrin
28
What is the function of the hormone gastrin? Where does it come from?
regulates secretion of stomach and motility- comes from enteroendocrine cells in the gastric glands
29
Explain the postive feedback process of pepsin
once HCl activates pepsionogen into pepsin, then pepsin itself can catalyze the conversion of pepsionogen to pepsin
30
What is the role of intrinsic factor? ( comes from cheifcells) What happens withouth this?
absorbs B12 | without- pernicious anemia
31
3 ways the stomach protects itself by producing mucosal barrier?
1. thick coating of bicarbonate rich mucus on stomach wall 2. epithelial cells joined by tight junctions 3. damaged epithelial are quickly replaced
32
Hormonal mechanism of gastric secretion
Gastrin stimulates HCl secretion by the stomach
33
Neural mechanism for gastric seceretion
vagus nerve, long and short reflexes, ACh is released to stimulate secretion of juices
34
What 3 chemicals stimulate parietal cell secretion of HCl?
ACh, gastrin, histamine
35
Stimulation of cephalic phase?
by sight/thought of food or by smell, taste
36
2 ways gastric phase is stimulated
1. stomach distention activates stretch receptors | 2. food chemicals activate chemoreceptors