Review Questions

Question 1

all of the following are true about DNA EXCEPT?

Answer 1

it is present in the cytoplasm of every cell

Question 2

segments or sequences of DNA that determine specific traits or characteristics are called

Answer 2

genes

Question 3

if a cell has a missing chromosome, that cell is referred to as

Answer 3

andeuploid

Question 4

which one of the following is an “address” of a gene along a chromosome that allows geneticists to locate a defective gene?

Answer 4

10p12

Question 5

which one of the following describes when a chromosome breaks and is reinserted in the wrong location?

Answer 5

inversion

Question 6

if a gene is “expressed, “ that means the trait carried by the gene will

Answer 6

be seen in the individual

Question 7

many genetic disorders demonstrate signs and symptoms that differ among affected individuals. this is known as

Answer 7

variable expressivity

Question 8

all of the following are true about autosomal recessive disorders EXCEPT:

Answer 8

affected individual usually have one unaffected parent

Question 9

what term is used to describe the visible characteristics that are created by the gene codes?

Answer 9

phenotype

Question 10

a collection of signs and symptoms that occur together and when concurrent lead to the diagnosis of the condition is called a(n)

Answer 10

syndrome

malformation

Question 11

all of the following are characteristics of Papillon-Lefevre syndrome EXCEPT

Answer 11

it is characterized by the lack of an enzyme called catalase

Question 12

patients with ectodermal dysplasia

Answer 12

a. have scant eyebrows and sparse fine hair
b. develop fevers of unknown origin
c. have conical shaped and numerous missing teeth
d. All of the above

Question 13

which one of the following is associated with paramedian lip pits?

Answer 13

van der Woude syndrome

Question 14

how is cherubism transmitted?

Answer 14

autosomal dominant

Question 15

All of the following are true about Cleidocranial dysplasia EXCEPT:

Answer 15

a. it is also known as Crouzon’s syndrome

Question 16

Cranisynostoses

Answer 16

a. involve premature closure of cranial sutures

Question 17

all of the following characterized Treacher-Collins syndrome EXCEPT:

Answer 17

there is hyperplasia of the zygomatic bone

Question 18

which of the following is not a feature of nevoid basal cell carcinoma syndrome?

Answer 18

coronoid hyperplasia

Question 19

which one of the following is false regarding osteogenesis imperfect?

Answer 19

dental manifestations include supernumerary and conical teeth

Question 20

what group of inherited skeletal defects, caused by a deficiency in osteoclast function, results in defective bone remodeling and a significant increase in bone density?

Answer 20

ostiopetrosis

Question 21

Café-au-lait pigmentation (spots) is

Answer 21

present in McCune-Albright syndrome

Question 22

the most significant manifestation of Gardner’s syndrome is

Answer 22

colon polyps that develop in the second decade of life

Question 23

Peutz-Jegher’s syndrome is characterized by all of the following EXCEPT:

Answer 23

there is mutation of the keratin 4 and 13 genes

Question 24

a benign tumor-like growth made up of normal mature cells in an abnormal number or distribution is known as a(n)

Answer 24

hamartoma

Question 25

which of the following statements concerning amelogenesis imperfect is incorrect:

Answer 25

dentin develops abnormally as part of this condition

Question 26

which condition is characterized by gray to violet opalescent teeth and obliterated pulp chambers and canals, and may occur in conjunction with osteogenesis imperfect?

Answer 26

dentinogenesis imperfect

Question 27

which statement about dentin dysplasia is incorrect?

Answer 27

it is sex-linked recessive

Question 28

which one of the following is a metabolic bone disorder that affects the development of bones, cementum, and periodontal ligament?

Answer 28

hypophospatasia