Rheumatoid Arthritis Flashcards
1
Q
What is characteristic of the joint inflammatory pattern in RA?
A
Symmetrical peripheral polyarthritis.
2
Q
Male:female ratio?
A
Women before menopause are affected 3x more often
3
Q
Peak age of onset?
A
30-50 years
4
Q
What are the genetic factors implicated in RA?
A
HLA-DR4
HLA-DRB1
…are both associated with increased risk and severity of RA
5
Q
The triggering antigen in this autoimmune chronic systemic disorder is unknown. What contributes to the ongoing synovial inflammation?
A
Interferons, interleukins
